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Items: 17

1.

Human PBMCs: Patients with HSPN vs. Patients with HSP

(Submitter supplied) Genes that were up-regulated in acute stage in HSPN patients compared with HSP patients, and that showed over 1.5-fold differences by the comparison between the two groups in the mean expression levels were selected.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
4 Samples
Download data: TXT
Series
Accession:
GSE149333
ID:
200149333
2.

Human peripheral blood cells (PB): Effect of Tocilizumab/MRA compared to methotrexate(MTX) treatments on rheumatoid arthritis(RA) patients.

(Submitter supplied) This microarray study was conducted along with SATORI study, the clinical trial evaluated 125 patients with active RA with an inadequate response to low dose of MTX. Patients were allocated to receive either Tocilizumab(TCZ) 8 mg/kg every 4 weeks (TCZ group) or MTX 8 mg/week (MTX/control group) for 24 weeks. Gene expression profiles (GEP) of 112 patients - 54 patients from TCZ group and 58 patients from MTX group - were obtained in this study.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
224 Samples
Download data: TXT
Series
Accession:
GSE35455
ID:
200035455
3.

Human peripheral blood cells: systemic lupus erythematosus vs healthy individual.

(Submitter supplied) Gene expression profiling of peripheral blood cells from patients with systemic lupus erythematosus (SLE) vs healthy individual (HI).
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
66 Samples
Download data: TXT
Series
Accession:
GSE20864
ID:
200020864
4.

Human PBMNCs: Control vs. Patients with Kawasaki disease

(Submitter supplied) Genes that were consistently up-regulated in KD patients compared with healthy controls, and that showed over 2.0 or 3.0-fold differences by the comparison between the two groups in the mean expression levels were selected.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
3 Samples
Download data: TXT
Series
Accession:
GSE17975
ID:
200017975
5.

Human peripheral blood cells: autoimmune diseases vs. healthy individuals

(Submitter supplied) Gene expression profiling of peripheral blood cells from patients with rheumatoid arthritis (RA)/ systemic lupus erythematosus (SLE)/ polyarticular type juvenile idiopathic arthritis (polyJIA)/ systemic-onset JIA (sJIA) vs healthy children (HC) and healthy individual (HI).
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
244 Samples
Download data: TXT
Series
Accession:
GSE17755
ID:
200017755
6.

48-h stretched human periodontal ligament cells

(Submitter supplied) Human periodontal ligament (HPDL) is continuously exposed to mechanical stress in vivo. In this study, in utilizing DNA chips, we analyzed the influences of mechanical stress on the gene expression profile of HPDL cells in vitro. HPDL cells were obtained from extracted first premolars of individuals undergoing tooth extraction for orthodontic treatment. Then, HPDL cells were applied to a stretch apparatus. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
2 Samples
Download data: TXT
Series
Accession:
GSE19118
ID:
200019118
7.

Transcriptome patterns for Acute Cellular Rejection in Recipients with Recurrent Hepatitis C after Liver Transplantation

(Submitter supplied) The histological evaluation of liver via biopsy remains as the standard for the diagnosis of both acute cellular rejection (ACR) and recurrent hepatitis C (RHC) after liver transplantation. Nevertheless, it is often difficult to diagnose ACR in HCV-positive recipients because of common co-existing and overlapping morphological changes with RHC. The aim of the study was to identify potential target genes for ACR in recipients with RHC. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
22 Samples
Download data: TXT
Series
Accession:
GSE13440
ID:
200013440
8.

Inherent gene signature of stage II and III colorectal cancer leads in individual recurrence

(Submitter supplied) Background & Aims. The current staging system for colorectal cancer (CRC) based on TNM classification allows prediction of potential recurrence. However, it does not necessarily make reliable personalized prediction of prognosis. In this paper we describe combination of clinicopathological data and gene signature of dissected tumor specimen with stage II and III CRC patients would improve the situation.. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
198 Samples
Download data: TXT
Series
Accession:
GSE12032
ID:
200012032
9.

Interactions of cytokines in peripheral blood cells from Systemic Lupus Erythematosus

(Submitter supplied) SLE patients are always with various disease manifestation. Various cytokines are pointed interacting and playing pathological roles in SLE although the etiopathology is still obscure. In this study, we aimed to investigate the effects of cytokine interactions in the immune response of SLE patients. Overexpressed interferon-inducible(IFI) genes were confirmed in peripheral blood from SLE patients. Using network-based analysis on the immune response-related genes, several networks including cytokines such as TNF and IFN-γ, or beta-estradiol(E2), were constructed. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
17 Samples
Download data: TXT
Series
Accession:
GSE12374
ID:
200012374
10.

Gene expression profile prospectively predicts peritoneal relapse after curative surgery of gastric cancer

(Submitter supplied) Purpose: Our study aimed to disclose the specific gene expression profile representing peritoneal relapses inherent in primary gastric cancers and to identify patients at high risk of peritoneal relapse in a prospective study on the basis of the molecular prediction. Experimental Design: RNA samples from 141 primary gastric cancer tissues after curative surgery were profiled using oligonucleotide microarrays covering 30,000 human probes. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
141 Samples
Download data: TXT
Series
Accession:
GSE15081
ID:
200015081
11.

Juvenile idiopathic arthritis: peripheral blood cells

(Submitter supplied) Systemic-onset juvenile idiopathic arthritis (soJIA) is a rheumatic disease in childhood characterized by systemic symptoms and a relatively poor prognosis. The peripheral leukocytes are thought to play the pathological role of soJIA although the exact cause is still obscure. In this study, we aimed to clarify the cellular functional abnormality in those cells. Here, we analyzed the gene expression profile in peripheral leukocytes from 51 patients with soJIA, 6 patients with poly-articular type JIA (polyJIA) and 8 healthy children utilizing DNA microarrays. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
65 Samples
Download data: TXT
Series
Accession:
GSE8361
ID:
200008361
12.

Non-cancerous liver infiltrating lymphocytes of hepatitis C and tumor-infiltrating lymphocytes

(Submitter supplied) Study goal is to disclose features of gene expressio profile of non-cancerous liver-infiltrating lymphocytes of type C hepatitis patients with hepatocellular carcinomas and tumor-infiltrating lymphocytes of type C hepatitis patients with hepatocellular carcinomas. Keywords: gene expression profile, non-cancerous liver-infiltrating lymphocytes, tumor-infiltrating lymphocytes, type C hepatitis, hepatocellular carcinoma
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
24 Samples
Download data
Series
Accession:
GSE10461
ID:
200010461
13.

Expression profile of peripheral blood mononuclear cells obtained from type C cirrhotic patients

(Submitter supplied) Study goal is to disclose features of gene expression profile of peripheral blood mononuclear cells obtained from type C cirrhotic patients with or without hepatocellular carcinomas. Keywords: gene expression profile, peripheral blood mononuclear cells, type C liver cirrhosis
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
62 Samples
Download data
Series
Accession:
GSE10459
ID:
200010459
14.

Gene expression profiles of head and neck squamous cell carcinoma (HNSCC)

(Submitter supplied) Distant metastasis is a major factor associated with poor prognosis in head and neck squamous cell carcinoma (HNSCC), but little is known of its molecular mechanisms. New markers that predict clinical outcome, in particular the ability of primary tumors to develop metastatic tumors, are urgently needed. Here, we identified neurotensin, highly expressed in HNSCCs in comparison with normal tissues, as an invasion-promoting factor in HNSCC by using microarray analysis of clinical samples. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
23 Samples
Download data: TXT
Series
Accession:
GSE9638
ID:
200009638
15.

Gene expression profiles of 25 normal human tissues

(Submitter supplied) We performed microarray experiments to identify genes specifically expressed in human tissues and investigated association of recombination rates with the tissue-specific genes. Keywords: Human tissue comparison
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
52 Samples
Download data: TXT
Series
Accession:
GSE8124
ID:
200008124
16.

Methylation-silenced genes in colorectal cancer cell lines

(Submitter supplied) Using an oligonucleotide array, we undertook a genome-wide search for genes upregulated following treatment with a demethylating agent in two CRC cell lines. Promoter methylation status was determined in 12 CRC cell lines and 11 CRC tissues. After the treatment, 350 genes were upregulated 1.5 fold or more. Six genes (PAGE-5, VCX, MAEL, GAGED2, UCHL1, and GAGE7), which contained putative 5'CpG islands in their promoter regions, were confirmed to be silenced in CRC cell lines. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by array
Platform:
GPL1291
4 Samples
Download data: TXT
Series
Accession:
GSE7687
ID:
200007687
17.

Gene expression profiles of head and neck squamous cell carcinoma (HNSCC) cell lines

(Submitter supplied) Chromosomal comparative genomic hybridization (CGH) and oligonucleotide microarrays were used to examine 8 HNSCC cell lines and a plot of gene expression levels relative to their position on the chromosome was produced. Three highly up-regulated genes, NT5C3, ANLN and INHBA, were identified on chromosome 7p14. These genes were subjected to quantitative real-time RT-PCR on cDNA and genomic DNA derived from 8 HNSCC cell lines. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1291
8 Samples
Download data: TXT
Series
Accession:
GSE7073
ID:
200007073
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