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Items: 9

1.

Bulk RNA-seq analyses of mandibular condylar cartilage in a post-traumatic temporomandibular joint osteoarthritis rabbit model

(Submitter supplied) We performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cells from post-traumatic temporomandibular joint osteoarthritis model to investigate the signaling pathways critical for cellular functions during temporomandibular joint osteoarthritis pathology.
Organism:
Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25392
12 Samples
Download data: XLSX
Series
Accession:
GSE232867
ID:
200232867
2.

Construction of ceRNA network based on an RNA‑seq shows prognostic lncRNA biomarkers in Perthes’ disease

(Submitter supplied) Construction of ceRNA network based on an RNA‑seq shows prognostic lncRNA biomarkers in Perthes’ disease
Organism:
Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL25392 GPL21255
16 Samples
Download data: TXT
Series
Accession:
GSE217908
ID:
200217908
3.

Transcriptional Changes Associated with rotator cuff repair

(Submitter supplied) In this study, we collected rabbit supraspinatus muscle tissue with higher temporal resolution (1, 2, 4, 8 weeks)after 8 wk tear followed by repair (n=4/group), to determine time-depenet transcriptional changes after repair. RNA sequencing and analyses were performed using standard techniques to identify a transcriptional timeline of rotator cuff muscle changes and related morphological sequelae.
Organism:
Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25392
34 Samples
Download data: CSV
Series
Accession:
GSE186320
ID:
200186320
4.

Effect of mechanical ventilation and mechanical ventilationon with positive end expiratory pressure(PEEP) application on diaphragmatic dysfunction in rabbits

(Submitter supplied) To investigate the effect of mechanical ventilation and mechanical ventilationon with PEEP application on diaphragmatic dysfunction, we established a model of mechanical ventilation on New Zealand rabbit, in which rabbits in the experimental group were ventilated with/without PEEP application for 48 hours continuously
Organism:
Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25392
9 Samples
Download data: XLSX
Series
Accession:
GSE228739
ID:
200228739
5.

Conservation and divergence of DNA methylation patterns and functions in vertebrates

(Submitter supplied) Cytosine DNA methylation is a heritable epigenetic mark present in most eukaryotic groups. While the patterns and functions of DNA methylation have been extensively studied in mouse and human, their conservation in other vertebrates remain poorly explored. In this study, we interrogated the distribution and function of DNA methylation in primary cells of seven vertebrate species including bio-medical models and key livestock species.
Organism:
Gallus gallus; Mus musculus; Canis lupus familiaris; Homo sapiens; Bos taurus; Sus scrofa; Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
9 related Platforms
62 Samples
Download data: BW, IGV
Series
Accession:
GSE175615
ID:
200175615
6.

PPARg activation enhances myelination and neurological recovery in premature rabbits with intraventricular hemorrhage

(Submitter supplied) We hypothesized that activation of PPARg would enhance myelination, reduce hydrocephalus, and promote neurological recovery in newborns with IVH. These hypotheses were tested in preterm rabbit model of IVH; autopsy brain samples from premature infants with and without IVH were analyzed. We found that IVH augmented PPARg expression in microglia of both preterm human infants and rabbit kits. The treatment with PPARg agonist or PPARg overexpression by adenovirus delivery further elevated PPARg levels in microglia, reduced pro-inflammatory cytokines, increased microglial phagocytosis, and improved oligodendrocyte progenitor cell (OPC) maturation in kits with IVH. more...
Organism:
Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25392
16 Samples
Download data: TXT
Series
Accession:
GSE182718
ID:
200182718
7.

Transcriptional Changes Associated with Acute to Chronic Stage Muscle Adaptations in a Model of Rotator Cuff Tendon Tear

(Submitter supplied) In this study, we collected rabbit supraspinatus muscle tissue with higher temporal resolution (1, 2, 4, 8, 16 weeks) post-tenotomy (n=6/group), where muscle degeneration occurs at later time points, to determine if transcriptional changes occur. RNA sequencing and analyses were performed using standard techniques to identify a transcriptional timeline of rotator cuff muscle changes and related morphological sequelae.
Organism:
Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25392
58 Samples
Download data: XLSX
Series
Accession:
GSE173234
ID:
200173234
8.

Transcriptome of CRPV-induced wart tissues

(Submitter supplied) Cottontail rabbit papillomavirus (CRPV) infection in susceptible animals represents an important model for studying papillomavirus pathogenesis and tumorigenesis. The goal of this project is to determine a comprehensive transcriptome of CRPV-induced wart tissues generated by different routes of infection.
Organism:
Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25392
10 Samples
Download data: TXT
Series
Accession:
GSE124211
ID:
200124211
9.

Gene expression in rabbit left atrial free wall and left atrial appendage

(Submitter supplied) RNA sequencing of dissected left atrial free wall and left atrial appendage of adult New Zealand White rabbit
Organism:
Oryctolagus cuniculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25392
2 Samples
Download data: XLSX
Series
Accession:
GSE117801
ID:
200117801
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