GPL2873[RGSE] - GEO DataSets

(Submitter supplied) Oligonucleotide aCGH profiles from 209 neuroblastoma tumor samples were generated using 44K, 105K or 1M microarrays. The 209th sample is represented by Sample GSM634116.

Organism:: Homo sapiens

Type:: Genome variation profiling by array

Platforms:: GPL16865 GPL8355 GPL2873
76 Samples

Download data: TXT

Series

Accession:: GSE45476

ID:: 200045476

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000359535.

High-resolution, genome-wide analysis of human metastatic neuroblastoma samples by array-Comparative Genomic Hybridization (aCGH)

(Submitter supplied) Less than 30% of children with high-risk (HR) metastatic neuroblastoma (NB) show a long survival (Pearson 2000). In order to identify novel molecular prognostic markers useful to better predict patients’ relapse risk estimation, we performed genome- and/or transcriptome-wide analyses of 129 stage 4 HR-NBs. This is the largest study for this NB subtype. Children older than 1 year of age at diagnosis were categorized as “short-survivors” (dead of disease within 5 years from diagnosis) and “long-survivors” (alive with an overall survival time > 5 years). more...

Organism:: Homo sapiens

Type:: Genome variation profiling by array

Platforms:: GPL2873 GPL5477
35 Samples

Download data: TXT

Series

Accession:: GSE35953

ID:: 200035953

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000257716.

High-resolution, genome-wide analysis of human metastatic neuroblastoma samples by array-Comparative Genomic Hybridization (aCGH)

(Submitter supplied) Neuroblastoma (NB) is an aggressive tumor that affects both infants and children. The disease outcome is greatly influenced by age of patient, stage, chromosome copy number aberrations (CNAs) and gene expression abnormalities. We analyzed, by microarray technology, genome and transcriptome of 3 groups of tumors of patients with metastatic disease: G1, stage 4S and MYCN single copy; G2, stage 4 younger than 18 months of age, MYCN single copy with no disease progression and G3, stage 4, older than 19 months, with unfavorable outcome. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by array

4 related Platforms
133 Samples

Download data: TXT

Series

Accession:: GSE25771

ID:: 200025771

Select item 2000284037.

Integrative genomic, transcriptomic and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.

(Submitter supplied) Background: Castration-resistant prostate cancer (CRPC) represents a therapeutic challenge for current medications. Methods: In order to explore the molecular mechanisms involved in CRPC progression and to identify new therapeutic targets, we analyzed a unique sample set of 11 castration-resistant prostate cancers and 7 advanced tumors by array-CGH and gene expression microarrays. The genome-wide DNA and RNA data were integrated to identify genes whose overexpression was driven by their amplification. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by genome tiling array

4 related Platforms
47 Samples

Download data: CEL, TXT

Series

Accession:: GSE28403

ID:: 200028403

Select item 2000283318.

Genome-wide profiling of endothelial progenitor cells in multiple myeloma: disease-relevant pathways and genomic markers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by genome tiling array

Platforms:: GPL570 GPL4091 GPL2873
64 Samples

Download data: CEL, TXT

Series

Accession:: GSE28331

ID:: 200028331

Analyze with GEO2R

Select item 2000283299.

Genome-wide array comparative genomic hybridization (aCGH) profiling of endothelial progenitor cells, and their comparison to tumor plasma cells, in multiple myeloma

(Submitter supplied) In multiple myeloma (MM), endothelial progenitor cells (EPCs) regulate tumor angiogenesis and disease progression. EPCs from 16 newly diagnosed patients with advanced MM were examined for genomic instability by aCGH to assess chromosomal gains and losses. Data were compared to aCGH results from corresponding CD138+ tumor plasma cells from these patients.

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platforms:: GPL4091 GPL2873
32 Samples

Download data: TXT, XLS

Series

Accession:: GSE28329

ID:: 200028329

Analyze with GEO2R

Select item 20001058310.

Genome-wide analysis of in-trans correlations between copy number and expression with application to human breast cancer

(Submitter supplied) Background: Genomic instability is a hallmark of cancer and is frequently reflected in the DNA copy number profile and the expression profile of genes. Methodology is needed to compare array-CGH data and microarray expression data in order to unveil effects of DNA copy number alterations of a gene on the expression of the gene itself (in-cis effects) and on other genes (in-trans effects). Results: We present a method for detection of gene dosage effects on gene expression that first searches for genome-wide in-cis associations between copy number and expression, and then investigates in-trans effects of these genes. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by array

Platform:: GPL2873
20 Samples

Download data: TXT

Series

Accession:: GSE10583

ID:: 200010583

Analyze with GEO2R

Select item 20001410911.

Oligonucleotide array CGH in high-risk neuroblastoma tumors

(Submitter supplied) We performed array CGH in high-risk neuroblastoma tumors in order to compare genome aberrations with expression of small non-coding RNAs.

Organism:: Homo sapiens

Type:: Genome variation profiling by array

Platforms:: GPL2873 GPL5477
33 Samples

Download data: TXT

Series

Accession:: GSE14109

ID:: 200014109

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001122512.

Array-comparative genomic hybridization by using DualChip® human cancer 1.1 arrays

(Submitter supplied) Tumors often harbor several genetic aberrations at both RNA and DNA level. Integration of expression data with copy number changes represents a powerful strategy to investigate genes involved in tumorigenesis. Here we describe a fluorescent array-based Comparative Genomic Hybridization protocol to be used on a commercial microarray platform optimized to detect cancer-related gene expression. This method will be valuable to use a single low-density array platform monitoring gene expression and copy number assessment in parallel. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by array; Genome variation profiling by genome tiling array

Platforms:: GPL6745 GPL2873
4 Samples

Download data: TXT

Series

Accession:: GSE11225

ID:: 200011225

Analyze with GEO2R

Select item 20000734413.

Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma

(Submitter supplied) Background There is much discussion in the cancer drug development community about how to incorporate molecular tools into early-stage clinical trials to assess target modulation, measure anti-tumor activity, and enrich the clinical trial population for patients who are more likely to benefit. Small, molecularly focused clinical studies offer the promise of the early definition of optimal biologic dose and patient population. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL2873
16 Samples

Download data: TIFF, TXT

Series

Accession:: GSE7344

ID:: 200007344

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000880414.

Precise Delination of 5q-Breakpoints and Detection of Hidden Aberrations in patients with MDS using Array CGH

(Submitter supplied) Isolated deletions of the long arm of chromosome 5 (del(5q)) are observed in 10% of myelodysplastic syndromes (MDS) and are associated with a more favorable prognosis, although the clinical course varies considerably. If one or more additional chromosomal aberration/s are present this correlates with a significant shorter overall survival. To assess the frequency of hidden abnormalities in cases with an isolated cytogenetic del(5q), we have performed a genome wide high resolution 44K 60mer oligonucleotide array CGH study using DNA from bone marrow cells of 12 MDS and one AML patient. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platforms:: GPL2873 GPL2879
13 Samples

Download data: TXT

Series

Accession:: GSE8804

ID:: 200008804

Select item 20000465915.

AML genome hybridization to HG44A

(Submitter supplied) CGH analysis was conducted for AML blasts with Agilent HG44A arrays. Keywords: disease state analysis

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL2873
32 Samples

Download data: TXT

Series

Accession:: GSE4659

ID:: 200004659

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GPL2873[RGSE] (15)
GEO DataSets
Homo sapiens cDNA FLJ44257 fis, clone TKIDN2015263
Homo sapiens cDNA FLJ44257 fis, clone TKIDN2015263
gi|34532678|dbj|AK126245.1|

Nucleotide
Foreword - Substance Abuse: Clinical Issues in Intensive Outpatient Treatment
Foreword - Substance Abuse: Clinical Issues in Intensive Outpatient Treatment
Chapter 5—Improving Quality and Measuring Outcomes of AOD Detoxification Service...
Chapter 5—Improving Quality and Measuring Outcomes of AOD Detoxification Services - Detoxification From Alcohol and Other Drugs
Appendix C—Excerpts From Quick Guide for Clinicians Based on TIP 45, Detoxificat...
Appendix C—Excerpts From Quick Guide for Clinicians Based on TIP 45, Detoxification and Substance Abuse Treatment - Incorporating Alcohol Pharmacotherapies Into Medical Practice

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