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Items: 5

1.

High-resolution transcriptional analysis of immunoglobulin variable regions reveals the absence of direct relationships between somatic hypermutation, nascent transcription and epigenetic marks

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster; Mus musculus; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
9 related Platforms
78 Samples
Download data: BEDGRAPH, BW
Series
Accession:
GSE202042
ID:
200202042
2.

High-resolution transcriptional analysis of immunoglobulin variable regions reveals the absence of direct relationships between somatic hypermutation, nascent transcription and epigenetic marks [PRO-seq]

(Submitter supplied) Analysis of chromatin marks, nascent transcription and mutational profiles at AID-target genes in human cell line and mouse
Organism:
Homo sapiens; Drosophila melanogaster; Mus musculus
Type:
Other
Platforms:
GPL21227 GPL29805 GPL17021
18 Samples
Download data: BW
Series
Accession:
GSE202041
ID:
200202041
3.

High-resolution transcriptional analysis of immunoglobulin variable regions reveals the absence of direct relationships between somatic hypermutation, nascent transcription and epigenetic marks [PRO-cap]

(Submitter supplied) Analysis of chromatin marks, nascent transcription and mutational profiles at AID-target genes in human cell line and mouse
Organism:
Drosophila melanogaster; Homo sapiens; Mus musculus
Type:
Other
4 related Platforms
11 Samples
Download data: BW
Series
Accession:
GSE202040
ID:
200202040
4.

KARR-seq reveals principles of high-order ribonucleoprotein structure assembly

(Submitter supplied) We designed KARR-seq, which reveals RNA-RNA interactions transcriptome-wide. The frequency of KARR-seq chimeras accurately reveals the physical distances between RNAs in vivo. Using KARR-seq, we systematically analyzed celullar effect on RNA-RNA interactions.
Organism:
Mus musculus; Vesicular stomatitis virus; Drosophila melanogaster; Homo sapiens; Respiratory syncytial virus
Type:
Other
5 related Platforms
67 Samples
Download data: PAIRS
Series
Accession:
GSE166155
ID:
200166155
5.

Increasing cell size remodels the proteome and promotes senescence 

(Submitter supplied) Cell size is tightly controlled in healthy tissues, but it is unclear how deviations in cell size affect cell physiology. To address this, we measured how the proteome changes with cell size. Protein concentration changes are widespread and predicted by subcellular localization, size-dependent mRNA concentrations, and protein turnover. As proliferating cells grow larger, concentration changes associated with cellular senescence are increasingly pronounced, suggesting that large size may be a cause rather than just a consequence of cell senescence. more...
Organism:
Homo sapiens; Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29805
23 Samples
Download data: BIGWIG
Series
Accession:
GSE208348
ID:
200208348
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Supplemental Content

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