GEO DataSets

(Submitter supplied) Hematopoietic malignancies are frequently characterized by karyotypic abnormalities. The development of targeted drugs has been pioneered with compounds against gene products of fusion genes caused by chromosomal translocations. While polysomies are equally frequent as translocations, for many of them we are lacking therapeutic approaches aimed at synthetic lethality. Here, we report two new cell lines, named MBU-7 and MBU-8, that differ in complete trisomies of chromosome 18, a partial trisomy of chromosome 7 and a tetrasomy of the p-arm of chromosome 8, but otherwise share the same mutational pattern and complex karyotype. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by array; Genome variation profiling by SNP array

Platform:

GPL18637

2 Samples

Download data: CEL, CYCHP

(Submitter supplied) #CytoScan750K_Array.cn.na32.3.annot.csv #%create_date=2012-11-27 GMT-08:00 16:16:00 #%chip_type=CytoScan750K_Array #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=37 #%genome-version-create_date=2009-02-00 #%dbSNP_date=2010-09-23 #%dbSNP_version=132 #%dgv-date=2010-10-00 #%dgv-version=10 #%hapmap-date=2008-01-08 #%hapmap-version=23 #%netaffx-annotation-date=2012-11-05 #%netaffx-annotation-netaffx-build=32.3 #CytoScan750K_Array.na32.3.annot.csv #%create_date=2012-11-27 GMT-08:00 16:17:00 #%chip_type=CytoScan750K_Array #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=37 #%genome-version-create_date=2009-02-00 #%dbSNP_date=2010-09-23 #%dbSNP_version=132 #%dgv-date=2010-10-00 #%dgv-version=10 #%hapmap-date=2008-01-08 #%hapmap-version=23 #%netaffx-annotation-date=2012-11-05 #%netaffx-annotation-netaffx-build=32.3 Protocol: see manufacturer's web site

Organism:

Homo sapiens

45 Series

1549 Samples

Download data: CSV