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Items: 4

1.

HSP27 (Heat Shock Protein 27, HSPB1) overexpression effect on bleomycin-induced PF (Pulmonary fibrosis) mice model

(Submitter supplied) To analyze the role of HSP27 in bleomycin (BLM)-induced pulmonary fibrosis in vivo, we used TG mice that conventionally overexpressed HSP27. Our previously reported that HSP27 plays an important role in pulmonary fibrosis. In mice overexpressing HSPB1, BLM-induced fibrotic regions and collagen deposits were increased compared with those in control BL6 mice. Following intratracheal treatment of BLM, the HSP25 TG mice showed an abundance of mononuclear and neutrophils cells in the alveoli, greater destruction of alveolar septa, intra-alveolar hyaline membrane formation, and a marked increase in collagen deposition compared with control BL6 mice.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11202
2 Samples
Download data: TXT
Series
Accession:
GSE233735
ID:
200233735

Analyze with GEO2R

2.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)

(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL10333. Protocol: see manufacturer's web site at http://www.agilent.com/
Organism:
Mus musculus
338 Series
1 Related Platform
4154 Samples
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Platform
Accession:
GPL11202
ID:
100011202

3.

C57BL6/N_HSP27Overexpression Transgenic(TG)_Bleomcyin (1.25mg/kg)

Organism:
Mus musculus
Source name:
Whole lung_14days_1.25mg/kg
Platform:
GPL11202
Series:
GSE233735
Download data: TXT
Sample
Accession:
GSM7433472
ID:
307433472

4.

C57BL6/N_Bleomcyin (1.25mg/kg)

Organism:
Mus musculus
Source name:
Whole lung_14days_1.25mg/kg
Platform:
GPL11202
Series:
GSE233735
Download data: TXT
Sample
Accession:
GSM7433471
ID:
307433471

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db=gds|term=GSE233735[Accession]|query=10|qty=2|blobid=MCID_671fc8a23b96c12390248013|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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