(Submitter supplied) Methylation of RNA on N6-adenosine (m6A) is emerging as a fundamental regulator of every aspect of RNA biology. RNA methylation directly impacts protein production to achieve quick modulation of dynamic biological processes. However, whether RNA methylation regulates mitochondrial function is not known, especially in neuronal cells which require a high energy supply and quick reactive responses. Here we show that m6A RNA methylation regulates mitochondrial function through promoting nuclear-encoded mitochondrial complex subunit RNA translation.
more...- Organism:
- Mus musculus
- Type:
- Other
- Platform:
- GPL21103
- 10 Samples
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