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Items: 6

1.

Roles of STAT3 and STAT5 in regulation of gene expression under Th17 differentiation

(Submitter supplied) Interleukin 2 (IL-2), a cytokine linked to human autoimmune diseases, limits IL-17 production. We show that deletion of Stat3 in T cells abrogates IL-17 production and attenuates autoimmunity associated with IL-2 deficiency. While STAT3 induces IL-17 and RORγt and inhibits Foxp3, IL-2 inhibited IL-17 independently of Foxp3 and RORγt. We found that STAT3 and STAT5 bound to multiple common sites across the Il17 genetic locus. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
4 Samples
Download data: CEL
Series
Accession:
GSE26551
ID:
200026551

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4546 Series
40 Related Platforms
58941 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261

3.

STAT5-deficient T cells, cultured 3 days in Th17 condition (expression)

Organism:
Mus musculus
Source name:
primary naïve CD4+ T cells from spleen and lymph nodes
Platform:
GPL1261
Series:
GSE26551 GSE26553
Download data: CEL
Sample
Accession:
GSM652876
ID:
300652876

4.

STAT5-wild type T cells, cultured 3 days in Th17 condition (expression)

Organism:
Mus musculus
Source name:
primary naïve CD4+ T cells from spleen and lymph nodes
Platform:
GPL1261
Series:
GSE26551 GSE26553
Download data: CEL
Sample
Accession:
GSM652875
ID:
300652875

5.

STAT3-deficient T cells, cultured 3 days in Th17 condition (expression)

Organism:
Mus musculus
Source name:
primary naïve CD4+ T cells from spleen and lymph nodes
Platform:
GPL1261
Series:
GSE26551 GSE26553
Download data: CEL
Sample
Accession:
GSM652874
ID:
300652874

6.

STAT3-wild type T cells, cultured 3 days in Th17 condition (expression)

Organism:
Mus musculus
Source name:
primary naïve CD4+ T cells from spleen and lymph nodes
Platform:
GPL1261
Series:
GSE26551 GSE26553
Download data: CEL
Sample
Accession:
GSM652873
ID:
300652873

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