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Items: 9

1.

Genome-wide hydroxymethylcytosine pattern changes in response to oxidative stress

(Submitter supplied) The TET-family enzymes (TETs) convert methylcytosine to hydroxymethylcytosine, a lately discovered epigenetic modification that can modulate transcription. While recent reports suggest that TETs may play a role in response to oxidative stress, this role remains uncertain. Here we show that Tet1 is sensitive to peroxide and report a global decrease in hydroxymethylcytosine in cells treated with BSO and in the intestinal epithelium of mice lacking the major antioxidant enzymes glutathione peroxidases 1 and 2. more...
Organism:
Mus musculus; Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL15456 GPL16173
6 Samples
Download data: WIG
Series
Accession:
GSE59718
ID:
200059718

SRA Run Selector

2.

Illumina HiScanSQ (Mus musculus)

Organism:
Mus musculus
77 Series
660 Samples
Download data
Platform
Accession:
GPL16173
ID:
100016173

3.

Illumina HiScanSQ (Homo sapiens)

Organism:
Homo sapiens
122 Series
2006 Samples
Download data
Platform
Accession:
GPL15456
ID:
100015456

4.

M-DKO2 [2]

Organism:
Mus musculus
Source name:
129 mouse with combined disruption of the GPx1 and GPx2
Platform:
GPL16173
Series:
GSE59718
Download data: WIG
Sample
Accession:
GSM1444197
ID:
301444197

SRA Run Selector

5.

M-WT2

Organism:
Mus musculus
Source name:
129 WT mouse
Platform:
GPL16173
Series:
GSE59718
Download data: WIG
Sample
Accession:
GSM1444196
ID:
301444196

SRA Run Selector

6.

M-DKO2 [1]

Organism:
Mus musculus
Source name:
129 mouse with combined disruption of the GPx1 and GPx2
Platform:
GPL16173
Series:
GSE59718
Download data: WIG
Sample
Accession:
GSM1444195
ID:
301444195

SRA Run Selector

7.

M-WT1

Organism:
Mus musculus
Source name:
129 WT mouse
Platform:
GPL16173
Series:
GSE59718
Download data: WIG
Sample
Accession:
GSM1444194
ID:
301444194

SRA Run Selector

8.

SY5Y-BSO

Organism:
Homo sapiens
Source name:
SY5Y treated with 500 μM BSO
Platform:
GPL15456
Series:
GSE59718
Download data: WIG
Sample
Accession:
GSM1444199
ID:
301444199

SRA Run Selector

9.

SY5Y-NT

Organism:
Homo sapiens
Source name:
SY5Y untreated
Platform:
GPL15456
Series:
GSE59718
Download data: WIG
Sample
Accession:
GSM1444198
ID:
301444198

SRA Run Selector

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db=gds|term=GSE59718[Accession]|query=4|qty=3|blobid=MCID_673b91a8a56b24050d3438f8|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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