U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 3

1.

Mutating Zta (182N) changes sequence specific DNA binding (5mC + 5hmC)

(Submitter supplied) The Epstein-Barr virus (EBV) bZIP transcription factor (TF) Zta is a sequence-specific DNA binding protein that recognizes both unmethylated and methylated DNA. To study the contribution of the conserved N182 amino acid to sequence specific Zta DNA binding, we replaced it with five other amino acids: serine (S), glutamine (Q), threonine (T), isoleucine (I), or valine (V). We used protein binding microarrays (PBMs) to evaluate sequence-specific DNA binding to four types of double-stranded DNA: 1) DNA with cytosine in both strands (DNA(C|C), 2) DNA with 5-methylcytosine (5mC, M) in one strand and cytosine in the second strand (DNA(5mC|C)), 3) DNA with 5-hydroxymethylcytosine (5hmC, H) in one strand and cytosine in the second strand (DNA(5hmC|C)), and 4) DNA with methylated cytosine in both strands in all CG dinucleotides (DNA(5mCG)). more...
Organism:
human gammaherpesvirus 4; synthetic construct
Type:
Other
Platform:
GPL24408
34 Samples
Download data: TXT
Series
Accession:
GSE115351
ID:
200115351
2.

Agilent custom HK design array v2[8mer]

(Submitter supplied) 8mer sequence depicted below is not the sequence represented on the array, but the targeted sequence. Please see the two array design files attached below for array probe sequences. Protocol: This protein binding microarray (PBM) involved binding GST-tagged proteins to custom-designed, double-stranded 44K Agilent microarrays in order to determine their sequence preferences. The method is described in Berger et al., Nature Biotechnology 2006.
Organism:
synthetic construct
3 Series
109 Samples
Download data
Platform
Accession:
GPL24408
ID:
100024408
3.

Zta_N182Q_C_rep2 (mC + 5hmC)

Organism:
human gammaherpesvirus 4
Source name:
Zta(N182Q), HK design
Platform:
GPL24408
Series:
GSE115351
Download data: TXT
Sample
Accession:
GSM3176397
ID:
303176397
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSM3176397[Accession]|query=1|qty=3|blobid=MCID_669b6c4656cb0a044eaa4a37|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center