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Items: 3

1.

Diphthamide modification of eEF2 is required for gut tumor-like hyperplasia induced by oncogenic Ras

(Submitter supplied) Eukaryotic elongation factor 2 (eEF2) undergoes a unique post-translational modification called diphthamidation. Although eEF2 diphthamidation is highly conserved, its pathophysiological function is still largely unknown. To elucidate the function of diphthamidation in tumor, we examined the involvement of diphthamidation pathway enzyme Dph5 in tumor progression in Drosophila adult gut. Expression of oncogenic RasV12 in gut intestinal stem cells (ISCs) and enteroblasts (EBs) causes hypertrophy and disruption of gut epithelia, and shortened lifespan. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL17277
14 Samples
Download data: TXT
Series
Accession:
GSE141201
ID:
200141201

PubMed Similar studies Analyze with GEO2R

2.

Agilent-040871 Drosophila melanogaster 8X60K with Spike (Probe Name version)

(Submitter supplied) Arrays of this design have barcodes that begin with 16040871 or 2540871. Protocol: See manufacturer's web site at http://www.agilent.com/.
Organism:
Drosophila melanogaster
2 Series
1 Related Platform
22 Samples
Download data
Platform
Accession:
GPL17277
ID:
100017277

PubMed Similar studies

3.

LacZIR_1

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197123
ID:
304197123

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