GSM4197124[Accession] - GEO DataSets

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Items: 3

Select item 2001412011.

Diphthamide modification of eEF2 is required for gut tumor-like hyperplasia induced by oncogenic Ras

(Submitter supplied) Eukaryotic elongation factor 2 (eEF2) undergoes a unique post-translational modification called diphthamidation. Although eEF2 diphthamidation is highly conserved, its pathophysiological function is still largely unknown. To elucidate the function of diphthamidation in tumor, we examined the involvement of diphthamidation pathway enzyme Dph5 in tumor progression in Drosophila adult gut. Expression of oncogenic RasV12 in gut intestinal stem cells (ISCs) and enteroblasts (EBs) causes hypertrophy and disruption of gut epithelia, and shortened lifespan. more...

Organism:: Drosophila melanogaster

Type:: Expression profiling by array

Platform:: GPL17277
14 Samples

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Accession:: GSE141201

ID:: 200141201

Select item 1000172772.

Agilent-040871 Drosophila melanogaster 8X60K with Spike (Probe Name version)

(Submitter supplied) Arrays of this design have barcodes that begin with 16040871 or 2540871. Protocol: See manufacturer's web site at http://www.agilent.com/.