GSM5728462[Accession] - GEO DataSets

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Items: 3

Select item 2001906651.

In vivo partial reprogramming in 4F mice

(Submitter supplied) Partial reprogramming by expression of reprogramming factors (Oct4, Sox2, Klf4 and cMyc) for short periods of time restores a youthful epigenetic signature to aging cells and extends the lifespan of a premature aging mouse model. However, the effects of longer-term partial reprogramming in physiologically aging wild-type mice are unknown. Here, we have performed various long-term partial reprogramming regimens, including different onset timings, during physiological aging in different mouse strains. more...

Organism:: Rattus norvegicus; Homo sapiens; Mus musculus

Type:: Methylation profiling by array

Platform:: GPL28271
168 Samples

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Accession:: GSE190665

ID:: 200190665

PubMed Full text in PMC Similar studies

Select item 1000282712.

Illumina HorvathMammalianMethylChip40 BeadChip

(Submitter supplied) Developed in the labs of Steve Horvath and Jason Ernst. The mammalian array platform applies to ALL mammals (humans, mouse, rat, sheep, horses, pigs, etc.). The array design is similar to the Illumina Infinium 450K array but it contains fewer up to 37492 CpGs. Additional material can be found on the Github page https://github.com/shorvath/MammalianMethylationConsortium/ A vignette on using the mammal methylation array with SeSAMe is available from https://bioconductor.org/packages/release/bioc/vignettes/sesame/inst/doc/mammal.html. more...