GSM6351383[Accession] - GEO DataSets

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Items: 4

Select item 2002085611.

Patterns of heterochromatin distribution alterations linked to transcriptional changes at Plasmodium falciparum clonally variant gene loci

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Plasmodium falciparum

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL21078 GPL26985
43 Samples

Download data: BEDGRAPH, NARROWPEAK, TXT

Series

Accession:: GSE208561

ID:: 200208561

Analyze with GEO2R

Select item 2002085602.

Patterns of heterochromatin distribution alterations linked to transcriptional changes at Plasmodium falciparum clonally variant gene loci [ChIP-seq]

(Submitter supplied) The survival of malaria parasites in the changing human blood environment largely depends on their ability to alter gene expression by epigenetic mechanisms. The active state of Plasmodium falciparum clonally variant genes is associated with euchromatin characterized by the histone mark H3K9ac, whereas the silenced state is characterized by H3K9me3-based heterochromatin. However, the localization of the euchromatin-heterochromatin transitions associated with expression switches in different clonally variant genes has not been characterized. more...