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Items: 3

1.

Zebrafish embryos exposed to the model hedgehog pathway inhibitor cyclopamine, as well as to the potential hedghog pathway disrupters SANT-2 and GANT-61.

(Submitter supplied) The hedgehog (Hh) signaling pathway is important for various developmental processes during embryogenesis and for homeostasis of adult tissue in vertebrates. Aberrant signaling results in severe birth defects and malignancies, respectively. The small molecules SANT-2 and GANT-61 were identified as potential Hh-pathway inhibitors in a reporter gene assay (Shh-light II cells). We aimed to analyze the effects of these compounds on the gene expression level in zebrafish embryos in comparison with the well known Hh-pathway inhibitor cyclopamine.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL13526
20 Samples
Download data: TXT
Series
Accession:
GSE29357
ID:
200029357

PubMed Similar studies Analyze with GEO2R

2.

D. rerio_UFZ_8x15KV4

(Submitter supplied) see at http://www.agilent.com
Organism:
Danio rerio
1 Series
20 Samples
Download data
Platform
Accession:
GPL13526
ID:
100013526

3.

Cyclopamine 5

Organism:
Danio rerio
Source name:
zebrafish embryo
Platform:
GPL13526
Series:
GSE29357
Download data: TXT
Sample
Accession:
GSM725695
ID:
300725695

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db=gds|term=GSM725695[Accession]|query=3|qty=2|blobid=MCID_6739ad73c743ad79f73f4c3e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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