GSM746841[Accession] - GEO DataSets

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Items: 4

Select item 2000301591.

Gene expression analysis of bone biospies from nine patients with endogenous Cushings syndrome before and after treatment

(Submitter supplied) Glucose intolerance and diabetes mellitus are classical parts of endogenous Cushing’s syndrome (CS), and insulin resistance is a feature of cortisol excess. CS patients display characteristics including hyperglycemia, abdominal obesity, reduced high-density lipoprotein cholesterol levels and elevated triglycerides, and arterial hypertension. Hypercortisolism is a well known cause of bone loss, and patients with CS frequently display low bone mass and fragility fractures. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4354
Platform:: GPL570
18 Samples

Download data: CEL

Series

Accession:: GSE30159

ID:: 200030159

Select item 43542.

Endogenous Cushing's Syndrome bone biopsies: pre- and post-surgery

Analysis of bone biopsies from Cushing’s syndrome (CS) patients, before and mean 3 months after surgical treatment. Excess GC-induced bone loss is a serious complication in patients with endogenous CS. Results provide insight molecular mechanisms by which excess GCs influence bone metabolism.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 specimen sets

Platform:: GPL570
Series:: GSE30159
18 Samples

Download data: CEL

DataSet

Accession:: GDS4354

ID:: 4354

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...