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Items: 1 to 20 of 59

1.

High-throughput transposon mutagenesis in the family Enterobacteriaceae reveals core essential genes and rapid turnover of essentiality

(Submitter supplied) The Enterobacteriaceae are a scientifically and medically important clade of bacteria, containing the gut commensal and model organism Escherichia coli, as well as several major human pathogens including Salmonella enterica and Klebsiella pneumoniae. Essential gene sets have been determined for several members of the Enterobacteriaceae, and the E. coli Keio single-gene deletion library is often regarded as a gold standard for gene essentiality studies. more...
Organism:
Enterobacter cloacae; Escherichia coli; Salmonella enterica subsp. enterica serovar Typhimurium; Citrobacter rodentium; Salmonella enterica subsp. enterica serovar Enteritidis; Klebsiella pneumoniae
Type:
Other
8 related Platforms
13 Samples
Download data: TXT, XLSX
Series
Accession:
GSE216013
ID:
200216013
2.

The transcriptional response to low temperature is weakly conserved across Enterobacteriales

(Submitter supplied) Bacteria respond to changes in their external environment like temperature by changing the transcription of their genes, but we know little about how these regulatory patterns evolve. We used RNA-seq to study the transcriptional response of a shift from 37°C to 15°C in wild-type Escherichia coli, Salmonella enterica, Citrobacter rodentium, Enterobacter cloacae, Klebsiella pneumoniae, and Serratia marcescens, as well as ∆rpoS strains of E. more...
Organism:
Salmonella enterica; Citrobacter rodentium; Enterobacter cloacae; Escherichia coli; Klebsiella pneumoniae; Serratia marcescens
Type:
Expression profiling by high throughput sequencing
6 related Platforms
64 Samples
Download data: TXT
Series
Accession:
GSE267531
ID:
200267531
3.

Drug efflux and lipid A modification by 4-L-aminoarabinose are key mechanisms of polymyxin B resistance in the sepsis pathogen Enterobacter bugandensis

(Submitter supplied) To investigate the mechanism of PmB resistance and heteroresistance in Enterobacter bugandensis by analysing the differential gene expression under PmB treatment.
Organism:
Enterobacter cloacae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32875
12 Samples
Download data: CSV
Series
Accession:
GSE218614
ID:
200218614
4.

TnpB homologs exapted from transposons are RNA-guided transcription factors

(Submitter supplied) Transposon-encoded tnpB and iscB genes encode RNA-guided DNA nucleases that promote their own selfish spread through targeted DNA cleavage and homologous recombination. These widespread gene families were repeatedly domesticated over evolutionary timescales, leading to the emergence of diverse CRISPR-associated nucleases including Cas9 and Cas12. We set out to test the hypothesis that TnpB nucleases may have also been repurposed for novel, unexpected functions other than CRISPR-Cas. more...
Organism:
Enterobacter cloacae; Escherichia coli; Enterobacter sp. BIDMC93
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other
4 related Platforms
51 Samples
Download data: BED, BW, XLSX
Series
Accession:
GSE245749
ID:
200245749
5.

Aminoglycoside heteroresistance in Enterobacter cloacae is driven by the cell envelope stress response.

(Submitter supplied) Enterobacter cloacae is a Gram-negative nosocomial pathogen of the ESKAPE priority group with increasing multi-drug resistance via the acquisition of resistance plasmids. However, E. cloacae can also display phenotypic antimicrobial resistance, such as heteroresistance or persistence. Here we report that E. cloacae ATCC 13047 and six strains isolated from patients with blood infections display heteroresistance or persistence to aminoglycosides. more...
Organism:
Enterobacter cloacae subsp. cloacae ATCC 13047
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33540
9 Samples
Download data: CSV
Series
Accession:
GSE236124
ID:
200236124
6.

Genomic and Transcriptional Characterisation of Carbapenem and Colistin Resistance Mechanisms in Klebsiella pneumoniae

(Submitter supplied) The transcriptional, epigenomic, and genomic profiles of K. pneumoniae isolates were characterised to identify novel colistin and carbapenem resistance mechanisms. The genomic DNA and total RNA of the isolates were isolated and sequenced on PacBio.
Organism:
Acinetobacter baumannii; Enterobacter asburiae; Enterobacter bugandensis; Enterobacter cloacae complex sp. R_G8; Enterobacter cloacae; Klebsiella pneumoniae
Type:
Expression profiling by high throughput sequencing; Other
12 related Platforms
22 Samples
Download data: CSV, DIFF, GFF, PDF
Series
Accession:
GSE217148
ID:
200217148
7.

Molecular Epidemiology of Enterobacterales Resistant to Antibiotics of Last Resort in Pregnant Women in Labour at a Tertiary Hospital

(Submitter supplied) This study aims to determine the epidemiology of Enterobacteriaceae resistant to antibiotics of last resort in pregnant women in labour at a tertiary hospital, Pretoria, South Africa. Rectal swabs shall be used to screen for colonisation with CRE and colistin-resistant Enterobacteriales in pregnant women during labour. Carbapenem and colistin-resistant Enterobacterales can cause the following infections: bacteraemia; nosocomial pneumonia; urinary tract infections, and intra-abdominal infections. more...
Organism:
Enterobacter roggenkampii; Enterobacter cloacae; Klebsiella pneumoniae
Type:
Methylation profiling by high throughput sequencing; Other
Platforms:
GPL27625 GPL32492 GPL32493
5 Samples
Download data: GFF, XLSX
Series
Accession:
GSE208573
ID:
200208573
8.

Colistin heteroresistance in Enterobacter cloacae is regualted by PhoPQ-dependent 4-amino-4-deoxy-L arabinose addition to lipid A

(Submitter supplied) We report the transcriptional expression from wild type, ΔphoPQ, and ΔpmrAB to understand their contribution to colistin resistance.
Organism:
Enterobacter cloacae subsp. cloacae ATCC 13047
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26251
3 Samples
Download data: XLS
Series
Accession:
GSE127802
ID:
200127802
9.

NextSeq 550 (Enterobacter cloacae)

Organism:
Enterobacter cloacae
1 Series
9 Samples
Download data
Platform
Accession:
GPL34277
ID:
100034277
10.

Illumina NovaSeq 6000 (Enterobacter cloacae subsp. cloacae ATCC 13047)

Organism:
Enterobacter cloacae subsp. cloacae ATCC 13047
1 Series
9 Samples
Download data
Platform
Accession:
GPL33540
ID:
100033540
11.

Illumina NextSeq 500 (Enterobacter cloacae)

Organism:
Enterobacter cloacae
2 Series
20 Samples
Download data
Platform
Accession:
GPL32875
ID:
100032875
12.

Illumina MiSeq (Enterobacter cloacae)

Organism:
Enterobacter cloacae
2 Series
2 Samples
Download data
Platform
Accession:
GPL32756
ID:
100032756
13.

Sequel (Enterobacter cloacae)

Organism:
Enterobacter cloacae
2 Series
2 Samples
Download data
Platform
Accession:
GPL32492
ID:
100032492
14.

Illumina HiSeq 4000 (Enterobacter cloacae subsp. cloacae ATCC 13047)

Organism:
Enterobacter cloacae subsp. cloacae ATCC 13047
1 Series
3 Samples
Download data
Platform
Accession:
GPL26251
ID:
100026251
15.

Enterobacter cloacae NCTC 9394 transposon mutant library

Organism:
Enterobacter cloacae
Source name:
NCTC 9394
Platform:
GPL32756
Series:
GSE216013
Download data
Sample
Accession:
GSM6654983
ID:
306654983
16.

E. cloacae wild-type, 15°C, replicate E

Organism:
Enterobacter cloacae
Source name:
ATCC13047
Platform:
GPL32875
Series:
GSE267531
Download data: TXT
Sample
Accession:
GSM8268334
ID:
308268334
17.

E. cloacae wild-type, 37°C, replicate E

Organism:
Enterobacter cloacae
Source name:
ATCC13047
Platform:
GPL32875
Series:
GSE267531
Download data: TXT
Sample
Accession:
GSM8268326
ID:
308268326
18.

E. cloacae wild-type, 15°C, replicate D

Organism:
Enterobacter cloacae
Source name:
ATCC13047
Platform:
GPL32875
Series:
GSE267531
Download data: TXT
Sample
Accession:
GSM8268318
ID:
308268318
19.

E. cloacae wild-type, 37°C, replicate D

Organism:
Enterobacter cloacae
Source name:
ATCC13047
Platform:
GPL32875
Series:
GSE267531
Download data: TXT
Sample
Accession:
GSM8268310
ID:
308268310
20.

E. cloacae wild-type, 15°C, replicate B

Organism:
Enterobacter cloacae
Source name:
ATCC13047
Platform:
GPL32875
Series:
GSE267531
Download data: TXT
Sample
Accession:
GSM8268302
ID:
308268302
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db=gds|term=txid550[Organism:exp]|query=14|qty=16|blobid=MCID_670cfe8e475a635e850d50a9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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