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Links from GEO DataSets

Items: 2

1.
Full record GDS2346

Reticulocyte binding-like homolog 2b knockout effect on 3D7 parasites

Analysis of reticulocyte binding-like homolog 2b (PfRh2b) null mutant 3D7 parasites. D10 isolate naturally lacks PfRh2b. Silencing of PfRh2b, a key invasion ligand, leads to altered invasion receptor dependency. Results provide insight into the molecular basis for invasion via an alternate pathway.
Organism:
Plasmodium falciparum
Type:
Expression profiling by array, transformed count, 2 development stage, 5 genotype/variation, 2 strain sets
Platform:
GPL1892
Series:
GSE3877
10 Samples
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2.
Full record GDS1350

SIR2 knockout effect on virulence gene family silencing and activation

Expression profiling of 3D7 silent information regulator 2 homolog (Sir2) knockout at ring stage, 8 hours post-invasion. Results identify Sir2-mediated, reversible heterochromatin silencing as one tier of epigenetic regulation of the antigenic variation var gene family.
Organism:
Plasmodium falciparum
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1892
Series:
GSE2369
4 Samples
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DataSet
Accession:
GDS1350
ID:
1350

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