GEO DataSets

Analysis of endometria of postmenopausal cynomolgus macaques treated with tamoxifen and low dose estradiol. Tamoxifen is a selective estrogen receptor modulator (SERM). Estrogen and SERM co-therapy is an alternative to estrogen and progestin, a treatment associated with increased breast cancer risk.

Organism:

Macaca fascicularis; Macaca mulatta

Type:

Expression profiling by array, count, 4 agent sets

Platform:

GPL3535

Series:

GSE14518

16 Samples

Download data: CEL, CHP

Analysis of colon, jejunum and lung from therapy-naïve, SIV-infected males. Gut and lung mucosa are important entry portals for pathogens and provide innate immune defense against infection. Results provide insight into molecular mechanisms underlying mucosal immune response during SIV infection.

Organism:

Macaca mulatta

Type:

Expression profiling by array, count, 2 infection, 3 tissue sets

Platform:

GPL3535

Series:

GSE51615

23 Samples

Download data: CEL

Temporal analysis of whole blood from 8 naturally SIV-infected SMs treated with recombinant RM IFNalpha2-IgFc (rmIFNα2) for 16 weeks. SIV infection of SMs is typically non-pathogenic. Results provide insight into effects of experimentally-augmented IFN-I signaling in chronically SIV-infected SMs.

Organism:

Cercocebus atys; Macaca mulatta

Type:

Expression profiling by array, transformed count, 2 agent, 8 individual, 6 time sets

Platform:

GPL3535

Series:

GSE35460

47 Samples

Download data: CEL

Analysis of PBMCs from SIVmac251-infected (12 wks) rhesus macaques (RMs) treated with an antibody against Programmed Death-1 (PD-1) for 14 days. Results provide insight into the molecular mechanisms by which PD-1 blockade enhances survival of SIV-infected RMs.

Organism:

Macaca mulatta

Type:

Expression profiling by array, transformed count, 3 agent, 2 infection sets

Platform:

GPL3535

Series:

GSE33933

10 Samples

Download data: CEL

Analysis of colorectal biopsies from SIV-infected Rhesus macaques (RM) and Sooty mangabeys (SM). Unlike AIDS-susceptible RMs, natural hosts such as SMs do not progress to AIDS. Results provide insight into molecular basis of immune activation following pathogenic immunodeficiency virus infections.

Organism:

Cercocebus atys; Macaca mulatta

Type:

Expression profiling by array, transformed count, 3 infection, 2 species, 3 time sets

Platform:

GPL3535

Series:

GSE29980

16 Samples

Download data: CEL

Temporal analysis of lymph nodes of SIVsmm infected Sooty mangabeys (SM) and SIVmac239 infected Rhesus macaques (RM). SIVsmm is non-pathogenic to host SM but origin of pathogens (HIV-2/SIVmac) to humans and RM. Results provide insight into the molecular basis of the differences in host responses.

Organism:

Cercocebus atys; Macaca mulatta

Type:

Expression profiling by array, count, 3 disease state, 3 infection, 2 species, 3 time sets

Platform:

GPL3535

Series:

GSE17626

28 Samples

Download data: CEL

Analysis of hippocampal cornu ammonis and dentate gyrus from young and aged female simians. Aging rhesus monkeys develop Metabolic Syndrome (MetS) symptoms and age-related cognitive decline similar to humans. Results provide insight into MetS-associated brain dysfunction in aging.

Organism:

Macaca mulatta

Type:

Expression profiling by array, count, 2 age, 2 tissue sets

Platform:

GPL3535

Series:

GSE11697

23 Samples

Download data: CEL

Analysis of hippocampus from simian immunodeficiency virus (SIV) encephalitis and control monkeys. Rhesus SIV encephalitis closely models human HIV-associated dementia (HAD) occurring in patients with advanced HIV. Results provide insight into molecular mechanisms underlying HAD cognitive deficits.

Organism:

Macaca mulatta

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL3535

Series:

GSE13824

36 Samples

Download data: CEL

Analysis of ovulatory, luteinizing follicles from a primate model of controlled ovulation at 0, 12, 24, 36 hr after exposure to an ovulatory (exogenous hCG) stimulus during the menstrual cycle. Results provide insight into molecular pathways associated with periovulatory events in primate follicle.

Organism:

Macaca mulatta

Type:

Expression profiling by array, count, 2 agent, 2 development stage, 4 time sets

Platform:

GPL3535

Series:

GSE22776

22 Samples

Download data: CEL

Analysis of corpus lutea (CLs) of animals treated with prostaglandin F2alpha (PGF2alpha). The CL is a transient endocrine gland that produces progesterone, a hormone needed to maintain pregnancy. Results provide insight into the mechanisms underlying the regression of CL mediated by PGF2alpha.

Organism:

Macaca mulatta; Macaca radiata

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL3535

Series:

GSE7971

6 Samples

Download data: CEL, CHP, EXP