Similar studies for GEO DataSets (Select 1233) - GEO DataSets

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Items: 20

Select item 12331.

Dysferlin deficiency effect on proximal and distal muscles

Comparison of the proximal quadriceps femoris muscle to the distal tibialis anterior muscle of 3 week old dysferlin deficient mutants. Dysferlin mutations can result in the neuromuscular disorders Limb-Girdle muscular dystrophy type 2B and Myoshi myopathy.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation, 2 tissue sets

Platform:: GPL81
Series:: GSE2629
12 Samples

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DataSet

Accession:: GDS1233

ID:: 1233

Select item 2000026292.

Dysferlin deficiency modulates the proximal-distal muscle transcriptome

(Submitter supplied) By comparing the transcriptome from proximal (quadriceps femoris, QF) and distal (tibialis anterior, TA)muscle groups in dysferlin deficient mouse muscle (the SJL mutation bred onto C57BL/10 to produces C57BL/10-SJL.Dysf) with proximal and distal muscle groups from control C57BL/10 mice of an equivalent age (3-weeks old, prior to the onset of overt pathology) we aim to address the issues of muscle selectivity in this this form of muscular dystrophy. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1233
Platform:: GPL81
12 Samples

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Series

Accession:: GSE2629

ID:: 200002629

Select item 2000021123.

Mouse Models for Muscular Dystrophy

(Submitter supplied) Comparative analysis of gene expression levels from hindlimb muscle tissue from 8 week old mouse models for muscular dystrophy. We have used mouse models with dystrophin-, sarcoglycan-, sarcospan-, or dysferlin-deficiency. Keywords = muscular dystrophy Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1770
26 Samples

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Series

Accession:: GSE2112

ID:: 200002112

Select item 2000032524.

Laminin-deficient muscular dystrophy, dy/dy diaphragm

(Submitter supplied) Laminin (merosin) deficient muscular dystrophy in dy/dy mouse diaphragm muscle, 8 weeks old Keywords: muscle, muscular dystrophy, laminin, merosin, diaphragm, mouse

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1778
Platform:: GPL339
8 Samples

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Series

Accession:: GSE3252

ID:: 200003252

Select item 17785.

Alpha2-laminin deficient dy/dy model of muscular dystrophy: diaphragm

Analysis of diaphragms of alpha2-laminin deficient dy/dy animals. Alpha-2 laminin is important in muscle cell attachment, and its deficiency underlies classical congenital muscular dystrophy. Results provide insight into the events that link alpha2-laminin deficiency with muscle fiber necrosis.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL339
Series:: GSE3252
8 Samples

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DataSet

Accession:: GDS1778

ID:: 1778

Select item 2000033076.

Comparative profiling in 13 muscle disease groups

(Submitter supplied) Summary: Genetic disorders of muscle cause muscular dystrophy, and are some of the most common inborn errors of metabolism. Muscle also rapidly remodels in response to training and innervation. Muscle weakness and wasting is important in such conditions as aging, critical care medicine, space flight, and diabetes. Finally, muscle can also be used to investigate systemic defects, and the compensatory mechansisms invoked by cells to overcome biochemical and genetic abnormalities. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS1956 GDS2855
Platforms:: GPL97 GPL96
242 Samples

Download data: CEL

Series

Accession:: GSE3307

ID:: 200003307

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 28557.

Various muscle diseases (HG-U133B)

Analysis of muscle biopsy specimens from patients with various muscle diseases. Results provide insight into the diagnosis and pathogenesis of muscle diseases.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 11 disease state sets

Platform:: GPL97
Series:: GSE3307
119 Samples

Download data: CEL

DataSet

Accession:: GDS2855

ID:: 2855

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 19568.

Various muscle diseases (HG-U133A)

Analysis of muscle biopsy specimens from patients with various muscle diseases. Results provide insight into the diagnosis and pathogenesis of muscle diseases.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 12 disease state sets

Platform:: GPL96
Series:: GSE3307
121 Samples

Download data: CEL

DataSet

Accession:: GDS1956

ID:: 1956

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000054259.

Spinal cord and dorsal root ganglion gene expression

(Submitter supplied) We used microarrays to test the fundamental quantitative differences between central and peripheral nervous system transcriptomes. Keywords: repeat

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2209
Platform:: GPL1261
6 Samples

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Series

Accession:: GSE5425

ID:: 200005425

Select item 220910.

Spinal cord and dorsal root ganglion

Analysis of spinal cord (SC) and dorsal root ganglion (DRG). The central nervous system (CNS) comprises the brain and SC; the peripheral nervous system (PNS) includes spinal and cranial nerves along with their associated DRGs. Results identify gene expression differences between the CNS and the PNS.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 tissue sets

Platform:: GPL1261
Series:: GSE5425
6 Samples

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DataSet

Accession:: GDS2209

ID:: 2209

Select item 20000558111.

Mouse Retina P7 Rs1h KO versus Control

(Submitter supplied) Genome-wide expression profiling of the retinoschisin deficient retina in C57CL/6 mice. Keywords: Genetic modification

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2636
Platform:: GPL339
6 Samples

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Series

Accession:: GSE5581

ID:: 200005581

Select item 263612.

Retinoschisis model

Analysis of retinas from postnatal day 7 mutants lacking retinoschisin (RS1h), an animal model for retinoschisis (RS). RS is a recessive retinal dystrophy accompanied by macular disease often resulting in early-onset vision loss. Results provide insight into the pathogenesis of RS.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL339
Series:: GSE5581
6 Samples

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DataSet

Accession:: GDS2636

ID:: 2636

Select item 20000355413.

Microarray Analysis of Retinal Gene Expression in the DBA/2J Model of Glaucoma

(Submitter supplied) Purpose: The DBA/2J mouse is a model for secondary angle-closure glaucoma due to iris atrophy and pigment dispersion, which ultimately leads to increased intraocular pressure (IOP). We sought to correlate changes in retinal gene expression with glaucoma-like pathology by performing microarray analysis of retinal RNA from DBA/2J mice at 3 months before disease onset, and at 8 months, after IOP elevation. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1728
Platform:: GPL1261
6 Samples

Download data: CEL

Series

Accession:: GSE3554

ID:: 200003554

Select item 172814.

DBA/2J model of glaucoma: retina

Analysis of retinas from strain DBA/2J with elevated intraocular pressure (IOP). A model for glaucoma, DBA/2J has mutations that lead to iris atrophy and pigment dispersion. These conditions result in increased IOP. Results provide insight into the molecular changes associated with IOP elevation.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 age, 2 disease state sets

Platform:: GPL1261
Series:: GSE3554
6 Samples

Download data: CEL

DataSet

Accession:: GDS1728

ID:: 1728

Select item 20000250715.

Cardiac and skeletal muscle gene expression profiles in dysferlin deficient mice

(Submitter supplied) Dysferlin is expressed in skeletal and cardiac muscle. However, dysferlin deficiency, namely limb girdle muscular dystrophy 2B (LGMD2B) and Myoshi myopathy, results in skeletal muscle weakness and spares the heart. This dichotomy could be caused by differential regulation of protective mechanisms. Therefore, we compared intraindividual mRNA expression profiles between cardiac and skeletal muscle in dysferlin-deficient SJL/J mice and normal C57BL/6 mice. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1247
Platform:: GPL81
20 Samples

Download data: CEL, EXP, RPT

Series

Accession:: GSE2507

ID:: 200002507

Select item 124716.

Dysferlin deficiency effect on skeletal and cardiac muscles

Comparison of skeletal and cardiac muscles of dysferlin deficient SJL/J animals. Dysferlin deficiency results in skeletal muscle weakness, but does not affect the heart. Dysferlin mutations can result in the neuromuscular disorders Limb-Girdle muscular dystrophy type 2B and Myoshi myopathy.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation, 2 tissue sets

Platform:: GPL81
Series:: GSE2507
20 Samples

Download data: CEL, EXP, RPT

DataSet

Accession:: GDS1247

ID:: 1247

Select item 20006993817.

Differential isoform expression and selective muscle involvement in muscular dystrophies

(Submitter supplied) To test the hypothesis that different muscles may express variable amounts of different isoforms of muscle genes, we applied a custom-designed exon microarray containing probes for 57 muscle-specific genes to assay the transcriptional profiles in sets of human adult, lower limb skeletal muscles.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL20574
137 Samples

Download data: GPR, TXT, XLS

Series

Accession:: GSE69938

ID:: 200069938

Select item 20000302218.

Gene expression profiling in dysferlinopathies using a dedicated muscle microarray

(Submitter supplied) We have performed expression profiling to define the molecular changes in dysferlinopathy using a novel dedicated microarray platform made with 3’-end skeletal muscle cDNAs. Eight dysferlinopathy patients, defined by western blot, immunohistochemistry and mutation analysis, were investigated with this technology. The expression profiles of patients with different clinical traits were independently obtained and hierarchical clustering was applied to discover patient-specific gene variations. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2677
10 Samples

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Series

Accession:: GSE3022

ID:: 200003022

Select item 10000267719.

Human Array 1.0

(Submitter supplied) Human Array 1.0 was constructed arraying on glass slides PCR-amplified cDNAs obtained from our archive of recombinant bacterial clones. This archive consists of 2688 different cDNA clones collected after systematic sequencing of human skeletal muscle cDNA libraries that contain only the 300-500 bp long 3’-portions of muscle transcripts. Protocol: 2688 different cDNA inserts were PCR amplified directly from bacterial cultures. more...

Organism:: Homo sapiens

1 DataSet
2 Series
16 Samples

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Platform

Accession:: GPL2677

ID:: 100002677

PubMed Similar studies

Select item 20002670120.

Expression data from post mortem porcine skeletal muscle

(Submitter supplied) We set up a pilot study using Affymetrix Gene Chip® Porcine Genome Arrays to evaluate the impact of time lags from death on gene expression profiling of porcine skeletal muscle at four post mortem time points (up to 24 hrs) during the routine processing of fresh tights

Organism:: Sus scrofa

Type:: Expression profiling by array

Platform:: GPL3533
12 Samples

Download data: CEL

Series

Accession:: GSE26701

ID:: 200026701

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