Similar studies for GEO DataSets (Select 1700) - GEO DataSets

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Items: 17

Select item 17001.

Anemia induced by acute renal rejection: peripheral blood lymphocytes

Analysis of peripheral blood lymphocytes from 4 renal allograft recipients with acute rejection and concurrent anemia. Compromised renal function after renal allograft transplantation often results in anemia. Results provide insight into the molecular events underlying anemia in acute rejection.

Organism:: Homo sapiens

Type:: Expression profiling by array, log2 ratio, 4 individual sets

Platform:: GPL3306
Series:: GSE3976
4 Samples

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DataSet

Accession:: GDS1700

ID:: 1700

Select item 2000039762.

Molecular profiling of anemia in acute renal allograft rejection

(Submitter supplied) Compromised renal function after renal allograft transplantation often results in anemia in the recipient. Molecular mechanisms leading to anemia during acute rejection are not fully understood; inadequate erythropoietin production and iron deficiency have been reported to be the main contributors. To increase our understanding of the molecular events underlying anemia in acute rejection, we analyzed the gene expression profiles of peripheral blood lymphocytes (PBL) from four pediatric renal allograft recipients with acute rejection and concurrent anemia, using DNA microarrays containing 9000 human cDNA clones (representing 7469 unique genes). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1700
Platform:: GPL3306
4 Samples

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Series

Accession:: GSE3976

ID:: 200003976

Select item 2000107333.

Expression data from skin, dermis, and epidermis of epithelial activated beta-catenin mutant mouse embryo

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
12 Samples

Download data: CEL, CHP, EXP

Series

Accession:: GSE10733

ID:: 200010733

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000107284.

Expression data from epidermis of epithelial activated beta-catenin mutant mouse embryo

(Submitter supplied) β-catenin signaling is required for hair follicle development, but it is unknown whether it is sufficient to activate expression of hair follicle genes in embryonic skin. To address this we profiled gene expression in epidermis from E15.5 KRT14-Cre Ctnnb1(Ex3)fl/+ embryos carrying an activating mutation in epithelial beta-catenin, and control littermate embryos. Keywords: Genetic modification

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
4 Samples

Download data: CEL, CHP, EXP, XLS

Series

Accession:: GSE10728

ID:: 200010728

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000107275.

Expression data from dermis of epithelial activated beta-catenin mutant mouse embryo

(Submitter supplied) β-catenin signaling is required for hair follicle development, but it is unknown whether it is sufficient to activate expression of hair follicle genes in embryonic skin. To address this we profiled gene expression in dermis from E15.5 KRT14-Cre Ctnnb1(Ex3)fl/+ embryos carrying an activating mutation in epithelial beta-catenin, and control littermate embryos. Keywords: Genetic modification

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
4 Samples

Download data: CEL, CHP, EXP, XLS

Series

Accession:: GSE10727

ID:: 200010727

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Select item 2000107266.

Expression data from skin of epithelial activated beta-catenin mutant mouse embryo

(Submitter supplied) β-catenin signaling is required for hair follicle development, but it is unknown whether it is sufficient to activate expression of hair follicle genes in embryonic skin. To address this we profiled gene expression in skin dissected from E14.5 KRT14-Cre Ctnnb1(Ex3)fl/+ embryos carrying an activating mutation in epithelial beta-catenin, and control littermate embryos. Keywords: Genetic modification

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
4 Samples

Download data: CEL, CHP, EXP, XLS

Series

Accession:: GSE10726

ID:: 200010726

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Select item 2000003437.

Molecular heterogeneity in acute renal allograft rejection

(Submitter supplied) The data set contains 67 array (lymphochip cDNA array), published in N Engl J Med 2003 Jul 10;349(2):125-38. PMID: 12853585. TITLE: Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. BACKGROUND: The causes and clinical course of acute rejection vary, and it is not possible to predict graft outcome reliably on the basis of available clinical, pathological, and genetic markers. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL271 GPL272
67 Samples

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Series

Accession:: GSE343

ID:: 200000343

Select item 2000015638.

Kidney Transplant Rejection and Tissue Injury by Gene Profiling of Biopsies and Peripheral Blood Lymphocytes

(Submitter supplied) We used DNA microarrays (HG-U95Av2 GeneChips) to determine gene expression profiles for kidney biopsies and peripheral blood lymphocytes (PBLs) in transplant patients. Sample classes include kidney biopsies and PBLs from patients with 1) healthy normal donor kidneys, 2) well-functioning transplants with no clinical evidence of rejection, 3) kidneys undergoing acute rejection, and 4) transplants with renal dysfunction without rejection. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS724
Platform:: GPL8300
62 Samples

Download data: CEL, EXP

Series

Accession:: GSE1563

ID:: 200001563

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Select item 7249.

Kidney transplant rejection expression profiling

Analysis of kidney transplant rejection by expression profiling of kidney biopsies and peripheral blood lymphocytes from patients. Results identify expression profiles unique to rejection, dysfunction without rejection, and well-functioning transplants.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 individual, 2 tissue sets

Platform:: GPL8300
Series:: GSE1563
62 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS724

ID:: 724

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20004709710.

Increased metallothionein expression reflects steroid resistance in renal allograft recipients.

(Submitter supplied) Steroid-refractory acute rejection is a risk factor for inferior renal allograft outcome. We aimed to gain insight into the mechanisms underlying steroid resistance by identifying novel molecular markers of steroid-refractory acute rejection. Eighty-three kidney transplant recipients (1995-2005), who were treated with methylprednisolone during a first acute rejection episode, were included in this study. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6883
40 Samples

Download data: TXT

Series

Accession:: GSE47097

ID:: 200047097

Select item 20012039811.

A peripheral blood gene expression signature diagnoses subclinical acute rejection

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL11154 GPL5175
153 Samples

Download data: CEL, TXT

Series

Accession:: GSE120398

ID:: 200120398

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20012039712.

A peripheral blood gene expression signature diagnoses subclinical acute rejection [validation]

(Submitter supplied) Histological features of acute rejection can be detected in surveillance biopsies despite stable graft function and can negatively impact graft outcomes. However, routine surveillance biopsies for detection of subclinical rejection are not generally performed due to potential risks and costs associated with repeated biopsies. Noninvasive biomarkers are required to facilitate early detection of acute rejection and borderline changes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL5175
65 Samples

Download data: CEL

Series

Accession:: GSE120397

ID:: 200120397

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20012039613.

A peripheral blood gene expression signature diagnoses subclinical acute rejection [discovery]

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
88 Samples

Download data: TXT

Series

Accession:: GSE120396

ID:: 200120396

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20006426114.

Molecular characterization of chronic antibody mediated rejection in kidney transplantation (mRNA CD4)

(Submitter supplied) Chronic antibody-mediated rejection (CAMR) represents the main cause of kidney graft loss, but its pathogenesis is unclear. In order to uncover the molecular mechanisms underlying this condition, we characterized the molecular signature of circulating peripheral blood mononuclear cells and, separately, of CD4+ T lymphocytes isolated from CAMR patients compared to kidney transplant recipients with normal graft function and histology. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
10 Samples

Download data: TXT

Series

Accession:: GSE64261

ID:: 200064261

Select item 20005167615.

Molecular characterization of chronic antibody mediated rejection in kidney transplantation (microRNA)

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL16770
9 Samples

Download data: TXT

Series

Accession:: GSE51676

ID:: 200051676

Select item 20005167516.

Molecular characterization of chronic antibody mediated rejection in kidney transplantation (mRNA)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
18 Samples

Download data: TXT

Series

Accession:: GSE51675

ID:: 200051675

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000649717.

Expression profile of syngeneic (sTX) and allogeneic kidney (aTX) transplantation compared to control (ctr) kidneys

(Submitter supplied) Microarray analyses provide a powerful approach to identify gene expression alterations following kidney transplantation. However, the heterogeneity of human kidney transplant specimens and the variation in sample preparation precludes conclusions regarding the underlying mechanisms of the observed alterations. We used a well defined experimental rat kidney transplantation model with consistent transplant and sample preparation procedures to analyze genome wide changes in gene expression after syngeneic (sTX) and allogeneic transplantation (aTX) four days after transplantation. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL1355
15 Samples

Download data: CEL, EXP

Series

Accession:: GSE6497

ID:: 200006497

PubMed Full text in PMC Similar studies Analyze with GEO2R

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