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Links from GEO DataSets

Items: 20

1.

Normal human muscle - U133 arrays

(Submitter supplied) vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old) Keywords = muscle Keywords = aging Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS287 GDS288
Platforms:
GPL96 GPL97
30 Samples
Download data
Series
Accession:
GSE362
ID:
200000362
2.
Full record GDS288

Muscle function and aging - male (HG-U133B)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL97
Series:
GSE362
15 Samples
Download data
DataSet
Accession:
GDS288
ID:
288
3.
Full record GDS287

Muscle function and aging - male (HG-U133A)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL96
Series:
GSE362
15 Samples
Download data
DataSet
Accession:
GDS287
ID:
287
4.

Effect of age on skeletal muscle

(Submitter supplied) Comparison of gene expression in young soleus muscle (3-4 months) with old soleus muscle (30-31 months). Keywords: parallel sample
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platforms:
GPL86 GPL87 GPL85
296 Samples
Download data
Series
Accession:
GSE353
ID:
200000353
5.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3643
Platform:
GPL1355
24 Samples
Download data: CEL
Series
Accession:
GSE10748
ID:
200010748
6.
Full record GDS3643

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 6 dose sets
Platform:
GPL1355
Series:
GSE10748
24 Samples
Download data: CEL
DataSet
Accession:
GDS3643
ID:
3643
7.

Skeletal muscle sarcopenia

(Submitter supplied) This series includes the global gene expression profile of the vastus lateralis muscle for 10 young (19-25 years old) and 12 older (70-80 years old) male subjects. Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
22 Samples
Download data: CEL
Series
Accession:
GSE1428
ID:
200001428
8.

Differential gene expression in resting human skeletal muscle of sedentary and highly-trained individuals.

(Submitter supplied) We used gene microarray analysis to compare the global expression profile of genes involved in adaptation to exercise training in skeletal muscle from chronically strength/resistance trained (ST), endurance trained (ET) and untrained control subjects (Con). Resting skeletal muscle samples (~100mg) were obtained from the vastus lateralis of 20 subjects (Con n=7, ET n=7, ST n=6; trained groups >8 years specific training). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6042
21 Samples
Download data: GPR
Series
Accession:
GSE9405
ID:
200009405
9.

EOM and hindlimb muscle development

(Submitter supplied) Conserved and muscle group-specific gene expression patterns shape postnatal development of the novel extraocular muscle phenotype. Comparison of postnatal development of extraocular and hindlimb muscle between birth and P45. Keywords: parallel sample
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS621
Platform:
GPL85
36 Samples
Download data: CEL
Series
Accession:
GSE903
ID:
200000903
10.
Full record GDS621

Extraocular and hindlimb muscle development

Analysis of hindlimb and extraocular muscle (EOM) between birth and postnatal day 45. Dissecting allotype-specific regulatory mechanisms may help explain differential muscle group sensitivity to a variety of metabolic and neuromuscular diseases.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 6 age, 2 tissue sets
Platform:
GPL85
Series:
GSE903
36 Samples
Download data: CEL
DataSet
Accession:
GDS621
ID:
621
11.

Woman skeletal muscle transcriptome with bed rest and countermeasures.

(Submitter supplied) Microgravity has a dramatic impact on human physiology, illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading to loss of muscle mass and structural disorders is necessary for the definition of efficient clinical and spaceflight countermeasures. We investigated the effects of long-term bed rest on transcriptome of soleus (SOL) and vastus lateralis (VL) muscles in healthy women (BRC group, n=8), and the potential beneficial impact of protein supplementation (BRN group, n=8) and of a combined resistance and aerobic training (BRE group, n=8). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6398
170 Samples
Download data: GPR
Series
Accession:
GSE14798
ID:
200014798
12.

mouse RPE/choroid age comparison - ATLAS arrays

(Submitter supplied) Young mice were compared to old mice (2 month vs 24 month) to determine gene changes that occur with aging in the mouse retinal pigmented epithelium/choroid of the eye. Keywords = retinal pigmented epithelium Keywords = aging Keywords = choroid Keywords: other
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL145 GPL144
12 Samples
Download data
Series
Accession:
GSE565
ID:
200000565
13.

Effect of Oxandrolone on Muscle in Duchenne Muscular Dystrophy

(Submitter supplied) Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were then treated for 3 months with oxandrolone (a synthetic anabolic steroid, 0.1 mg/kg/day) and the studies repeated. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS1333 GDS1334
Platforms:
GPL96 GPL97
12 Samples
Download data
Series
Accession:
GSE1764
ID:
200001764
14.
Full record GDS1334

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133B)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL97
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1334
ID:
1334
15.
Full record GDS1333

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133A)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL96
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1333
ID:
1333
16.

Effect of acute creatine monohydrate supplementation on skeletal muscle transcriptome

(Submitter supplied) Expression profiling of vastus lateralis muscle of young, healthy, non-obese men supplemented with creatine monohydrate vs. placebo for 10 days. Results identify transcriptional pathways activated in skeletal muscles as a result of acute creatine monohydrate supplementation. Keywords: Supplementation response.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5216
12 Samples
Download data: GPR
Series
Accession:
GSE7877
ID:
200007877
17.

Expression Profile of Skeletal Muscle from Young and Aged C57B1/6 Mice

(Submitter supplied) Our laboratory wanted to define the transcription profile of aged skeletal muscle. For this reason, we performed a triplicate microarray study on young (3 weeks) and aged (24 months) gatrocnemius muscle from wild-type C57B16 Mice Keywords: other
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
6 Samples
Download data: CEL, CHP, EXP
Series
Accession:
GSE14678
ID:
200014678
18.

Genomic profiling of aged rat skeletal muscle

(Submitter supplied) a genomic profile of aged rat sceletal muscle with diffrent degrees of sensorimotor disturbances. Keywords: age skeletal muscle sensorimotor disturbances
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL1921
9 Samples
Download data: GPR
Series
Accession:
GSE6229
ID:
200006229
19.

Muscle, normal extraocular, profile

(Submitter supplied) Molecular definition of human extraocular muscles (EOM). Human EOM were compared with limb (quadriceps femoris) muscle. Keywords = Eye Keywords = EOM Keywords = Muscle Keywords = DMD Keywords = Myasthenia Gravis Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS525
Platform:
GPL96
5 Samples
Download data: CEL
Series
Accession:
GSE873
ID:
200000873
20.
Full record GDS525

Extraocular and limb muscle comparison

Molecular definition of extraocular muscle (EOM). Autopsy superior rectus EOM compared with biopsy limb quadriceps femoris muscle.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL96
Series:
GSE873
5 Samples
Download data: CEL
DataSet
Accession:
GDS525
ID:
525
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