Similar studies for GEO DataSets (Select 200004492) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Links from GEO DataSets

Items: 14

Select item 2000044921.

Transcriptional reprogramming during reloading of atrophied rat soleus muscle

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL153
23 Samples

Download data

Series

Accession:: GSE4492

ID:: 200004492

Select item 2000010842.

HS-R5

(Submitter supplied) 14 days hindlimb suspended, 5 days reloaded m. soleus RNA was isolated from cryosections using RNeasy kit (Qiagen). 5 microgram total RNA was subjected to microarray analysis. Keywords: time-course

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL153
5 Samples

Download data

Series

Accession:: GSE1084

ID:: 200001084

Select item 2000006733.

Muscle unloading and reloading

(Submitter supplied) Examination of effect of mechanical loading induced by hindlimb suspension, and subsequent reloading, in soleus muscle in 14 day old female pathogen–free Wistar rats. Keywords = skeletal muscle Keywords = atrophy Keywords: other

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL153
18 Samples

Download data

Series

Accession:: GSE673

ID:: 200000673

Select item 2000012934.

Hindlimb suspension and reloading study

(Submitter supplied) Analysis of effect of hindlimb suspension and reloading on C57Bl/6 mouse soleus muscle. Experimental groups examined: -Control mice, 14 days -Hindlimb suspension for 7 days -Hindlimb suspension for 7 days, and subsequent reloading for 1 day -Hindlimb suspension for 7 days, and subsequent reloading for 7 days Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1097
23 Samples

Download data

Series

Accession:: GSE1293

ID:: 200001293

Select item 2000012875.

Reloaded 7 days

(Submitter supplied) Hindlimb suspension for 7 days, subsequent reloading for 7 days Keywords: repeat sample

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1097
5 Samples

Download data

Series

Accession:: GSE1287

ID:: 200001287

Select item 2000012866.

Reloaded 1 day

(Submitter supplied) Hindlimb suspended for 7 days, subsequent reloading for 1 day Keywords: repeat sample

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1097
6 Samples

Download data

Series

Accession:: GSE1286

ID:: 200001286

Select item 2000012857.

Hindlimb suspension

(Submitter supplied) Hindlimb suspended for 7 days Keywords: repeat sample

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1097
6 Samples

Download data

Series

Accession:: GSE1285

ID:: 200001285

Select item 2000012848.

Control

(Submitter supplied) Control mice, 14 days Keywords: repeat sample

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1097
6 Samples

Download data

Series

Accession:: GSE1284

ID:: 200001284

Select item 2000105339.

Effects of spaceflight on murine skeletal muscle gene expression

(Submitter supplied) Spaceflight results in a number of adaptations to skeletal muscle, including atrophy and shifts towards faster muscle fiber types. To identify changes in gene expression that may underlie these adaptations, microarray expression analysis was performed on gastrocnemius from mice flown on the STS-108 shuttle flight (11 days, 19 hours) versus mice maintained on earth for the same period. Additionally, to identify changes that were due to unloading and reloading, microarray analyses were conducted on calf muscle from ground-based mice subjected to hindlimb suspension (12 days) and mice subjected to hindlimb suspension plus a brief period of reloading (3.5 hours) to simulate the time between landing and sacrifice of the spaceflight mice.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL339
23 Samples

Download data: CEL

Series

Accession:: GSE10533

ID:: 200010533

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001777610.

MicroRNA expression in rat soleus muscle during atrophy induced by hindlimb suspension

(Submitter supplied) The objective of the study was to identify microRNAs expressed in the rat soleus muscle and determine if their expression was changed in response to hindlimb suspension.

Organism:: Rattus norvegicus; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL9082
9 Samples

Download data: TXT

Series

Accession:: GSE17776

ID:: 200017776

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20003794411.

Sparing of muscle mass and function by passive loading in an experimental intensive care unit model

(Submitter supplied) Critically ill intensive care unit (ICU) patients commonly develop severe muscle wasting and impaired muscle function, leading to delayed recovery, with subsequent increased morbidity and financial costs, and decrease quality of life of survivors. Acute Quadriplegic Myopathy (AQM) is one of the most common neuromuscular disorders associated with ICU-acquired muscle weakness. Although there are no available treatments for the ICU-acquired muscle weakness, it has been demonstrated that early mobilization can improve its prognosis and functional outcomes. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS4563
Platform:: GPL6247
46 Samples

Download data: CEL

Series

Accession:: GSE37944

ID:: 200037944

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 456312.

Passive loading effect on gastrocnemius muscle of intensive care unit model: time course

Temporal analysis of loaded leg gastrocnemius of females (subjected to neuromuscular blockade, mechanical ventilation) following unilateral passive mechanical loading (PML). Results provide insight into molecular basis of the beneficial effects of PML on muscle mass and function in this ICU model.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 protocol, 3 time sets

Platform:: GPL6247
Series:: GSE37944
46 Samples

Download data: CEL

DataSet

Accession:: GDS4563

ID:: 4563

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20024886913.

Arrestin domain containing 2 is highly induced in response to disuse in young and aged muscle and is sufficient to lower C2C12 myotube diameter

(Submitter supplied) Arrestin Domain Containing 2 and 3 (Arrdc2/3) are genes whose mRNA contents are decreased in young skeletal muscle following mechanical overload. Arrdc3 is linked to the regulation of signaling pathways in non-muscle cells that could influence skeletal muscle size. Despite a similar amino acid sequence, Arrdc2 function remains undefined. The purpose of this study was to further explore the relationship of Arrdc2/Arrdc3 expression with changes in mechanical load in young and aged muscle and define the effect of Arrdc2/3 expression on myotube diameter. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24247
10 Samples

Download data: XLSX

Series

Accession:: GSE248869

ID:: 200248869

PubMed Similar studies

Select item 20025050614.

RNA-sequencing of soleus muscle from Mustn1 heterozygous KO-first mice and wildtype littermates

(Submitter supplied) To uncover novel genes and molecular pathways important for skeletal muscle remodeling and regeneration, we used a mouse hindlimb unloading and reloading protocol. We then performed analysis of global gene expression by RNA-sequencing (RNA-seq), looking at the transition from muscle unloading to reloading (GSE237099). This study focuses on the microprotein Mustn1 (Musculoskeletal embryonic nuclear protein 1, also known as Mustang), which consists of 82 amino acids. more...