Similar studies for GEO DataSets (Select 200010304) - GEO DataSets

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Items: 20

Select item 2000103041.

Gene expression in AES-2 clonal isolates of Pseudomonas aeruginosa

(Submitter supplied) Pseudomonas aeruginosa (P. aeruginosa) lung infection is a significant cause of mortality in patients with cystic fibrosis (CF). Most CF patients acquire unique P. aeruginosa strains from the environment; however clonal strains have been identified in CF communities in several countries. Two clonal strains infect 10% to 40% of patients in three CF clinics in mainland eastern Australia. The expression profiles of four planktonically-grown isolates of one Australian clonal strain (AES-2), and four non–clonal CF P. more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Platform:: GPL84
8 Samples

Download data: CEL, CHP

Series

Accession:: GSE10304

ID:: 200010304

Select item 2000061222.

Gene expression in PAO1, clonal AES-1 and non-clonal isolates of Pseudomonas aeruginosa

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Platform:: GPL84
18 Samples

Download data: CEL, CHP

Series

Accession:: GSE6122

ID:: 200006122

Select item 2000281523.

Pseudomonas aeruginosa gene expression in artificial sputum medium using a broad capture array designated the PANarray

(Submitter supplied) The PANarray design (GPL13324) contains the genes of eight P. aeruginosa genomes in non-redundant format, thus allowing identification of expression of non-PAO1 and other P. aeruginosa genes.

Organism:: Pseudomonas aeruginosa; Pseudomonas aeruginosa PACS2; Pseudomonas aeruginosa 2192; Pseudomonas aeruginosa LESB58; Pseudomonas aeruginosa AES-1R; Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa C3719; Pseudomonas aeruginosa UCBPP-PA14; Pseudomonas aeruginosa PA7

Type:: Expression profiling by array

Platform:: GPL13324
8 Samples

Download data: TXT

Series

Accession:: GSE28152

ID:: 200028152

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000685344.

Using RNA Seq to define the regulon of the Pseudomonas aeruginosa transcription factor Anr in low-oxygen colony biofilms.

(Submitter supplied) Purpose : The goal of this study was to use RNA Seq to define the regulon of the transciption factor Anr by comparing global transcriptional profiles of Pseudomonas aeruginosa strain PAO1 and a clinical isolate with their isogenic ∆anr mutants, grown in colony biofilms at 1% oxygen. Methods : mRNA profiles were generated for laboratory strain PAO1 and for a clinical isolate J215, as well as for ∆anr derivatives of each strain, in duplicate, by deep sequencing. more...

Organism:: Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL18287 GPL18782
8 Samples

Download data: XLSX

Series

Accession:: GSE68534

ID:: 200068534

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000103625.

Expression data from sequential P. aeruginosa cystic fibrosis (CF) isolates

(Submitter supplied) To provide a more detailed survey of adaptive changes in the physiology of P. aeruginosa (PA) during long-term infection of the cystic fibrosis (CF) lung, we performed a comparative proteome and transcriptome analysis of a set of isogenic sequential non-mutator and mutator isolates from three selected CF patients. Recently, we showed that during CF lung persistence PA mutators converge to a virulence-attenuated phenotype. more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Platform:: GPL84
24 Samples

Download data: CEL

Series

Accession:: GSE10362

ID:: 200010362

Select item 2000067416.

Responses of Pseudomonas aeruginosa to low oxygen

(Submitter supplied) In order to understand how Pseudomonas aeruginosa responds to low oxygen we grew strain PAO1 with 3 different oxygen concentrations: 2%, 0.4% and 0% supplemented with nitrate as an electron acceptor. Gene expression under these conditions was compared to that of cells grown with 20% oxygen. Keywords: Comparison of transcriptome profiles

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Dataset:: GDS2893
Platform:: GPL84
8 Samples

Download data: CEL

Series

Accession:: GSE6741

ID:: 200006741

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 28937.

Response to low oxygen conditions

Analysis of Pseudomonas aeruginosa strain PAO1 grown with 2% or 0.4% oxygen (O2), or without O2 but with nitrate instead. In cystic fibrosis (CF) lungs, PAO1 grows to high densities in mucopurulent material depleted in O2. Results provide insight into mode of growth in CF lungs.

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array, count, 4 dose, 3 stress sets

Platform:: GPL84
Series:: GSE6741
8 Samples

Download data: CEL

DataSet

Accession:: GDS2893

ID:: 2893

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000404618.

PAHM4 vs PAO1 37C LB

(Submitter supplied) Pseudomonas aeruginosa strains PAHM4 and PAO1 were grown at 37C on LB and RNA was hybridized on the Affymetrix P. aeruginosa chip to compare transcript differences from a BQ isolate to a well characterized wound isolate.

Organism:: Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa PAHM4

Type:: Expression profiling by array

Platform:: GPL84
6 Samples

Download data: CEL

Series

Accession:: GSE40461

ID:: 200040461

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000332759.

Gene expression in P. aeruginosa cystic fibrosis isolates grown on Nematode Growth Medium

(Submitter supplied) Pseudomonas aeruginosa (P. aeruginosa) lung infection is a significant cause of mortality in patients with cystic fibrosis (CF). Existing experimental data in our lab showed significantly different levels of virulence of "early" and "late" P. aeruginosa infection isolates in a C. elegans slow killing model. We wished to examine the expression profile of these isolates in order to explore genes that may be responsible for the observed differences. more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Platform:: GPL84
8 Samples

Download data: CEL, CHP

Series

Accession:: GSE33275

ID:: 200033275

Select item 20008377310.

Using RNA Seq to validate transcriptional profile data obtained by Nanostring analysis

(Submitter supplied) Purpose : The goal of this study was to use RNA Seq to validate transcriptional data of two clinical isolates focussing on a subset of 74 transcript that were selected specifically for Nanostring analysis. Methods : mRNA profiles were generated for the clinical isolates FRD1 and CI224_M, in duplicate, by deep sequencing. Strains were grown for 8 hours in LB medium at 37C prior to RNA harvest. Ribosomal RNA was removed using the Ribi-Zero rRNA Removal Kit (Epicentre). more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21297
4 Samples

Download data: XLSX

Series

Accession:: GSE83773

ID:: 200083773

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20000288511.

PA2384 and iron starvation in P. aeruginosa

(Submitter supplied) The gene PA2384 in Pseudomonas aeruginosa PAO1, annotated originally as unknown function, has been previously shown to be dramatically responsive to iron limitation. In the present study, PA2384 is shown by bioinformatics analysis to have a weak similarity to the N-termini DNA binding domain of fur, a well-known ferric uptake regulator. To experimentally investigate the function of PA2384 P. aeruginosa PAO1 recombinant (pUCP20::PA2384) overexpressing PA2384 and PA2384 knock-out mutant PAO1-23844 are constructed and studied. more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Dataset:: GDS1910
Platform:: GPL84
12 Samples

Download data

Series

Accession:: GSE2885

ID:: 200002885

Select item 191012.

Iron starvation effect on PA2384 null mutant

Analysis of PAO1 strain PA2384 null mutant grown under iron-limiting conditions. PA2384 is responsive to iron limitation and is weakly similar to the ferric uptake regulator fur. RNA extracted from cells at various stages of growth. Results provide insight into the function of PA2384.

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array, count, 2 genotype/variation, 3 other sets

Platform:: GPL84
Series:: GSE2885
12 Samples

Download data

DataSet

Accession:: GDS1910

ID:: 1910

Select item 20000770413.

In vivo evidence of Pseudomonas aeruignosa nutrient acquisition and pathogenesis in the cystic fibrosis lung

(Submitter supplied) One of the hallmarks of Pseudomonas aeruginosa cystic fibrosis (CF) infection is very high-cell-density (HCD) replication in the lung, allowing this bacterium to induce virulence controlled by HCD quorum-sensing systems. However, the nutrient sources sustaining HCD replication in this chronic infection is largely unknown. Hence, understanding the nutrient factors contributing to HCD in the CF lung will yield new insights into the 'metabolic pathogenicity' and potential treatment of CF infections caused by P. more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Dataset:: GDS2869
Platform:: GPL84
14 Samples

Download data: CEL, CHP

Series

Accession:: GSE7704

ID:: 200007704

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 286914.

Pseudomonas aeruginosa from cystic fibrosis lungs

Analysis of Pseudomonas aeruginosa isolates from sputa of cystic fibrosis (CF) lungs following growth in minimal media. P. aeruginosa infected CF lungs are characterized by high cell density (HCD) replication of this pathogen. Results provide insight into the mechanisms sustaining HCD replication.

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array, count, 4 growth protocol, 2 protocol, 3 specimen sets

Platform:: GPL84
Series:: GSE7704
14 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS2869

ID:: 2869

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20000925515.

P. aeruginosa PAO1 PA2663 mutant vs. wild type strain

(Submitter supplied) P. aeruginosa PAO1 wild type and PA2663 mutant strains expression in biofilm cells relative to P. aeruginosa PAO1 wild type strain expression in biofilm cells. All samples cultured in LB with glass wool Keywords: Biofilm

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Platform:: GPL84
2 Samples

Download data: CEL

Series

Accession:: GSE9255

ID:: 200009255

Select item 20001859416.

P. aeruginosa PA14 gene expression in artificial sputum medium (ASMDM)

(Submitter supplied) Pseudomonas aeruginosa airway infection is the leading cause of morbidity and mortality in cystic fibrosis (CF) patients. In vitro models that closely mimic CF sputum are needed to improve understanding of the pathobiology of P. aeruginosa in the CF airway. We developed an artificial sputum medium (ASMDM) that more closely resembles the composition of CF sputum than current media. In order to validate the utility of ASMDM, we used GeneChip microarrays to compare expression data of P. more...

Organism:: Pseudomonas aeruginosa UCBPP-PA14; Pseudomonas aeruginosa

Type:: Expression profiling by array

Dataset:: GDS4250
Platform:: GPL84
8 Samples

Download data: CEL, CHP

Series

Accession:: GSE18594

ID:: 200018594

Select item 425017.

Artificial medium mimicking cystic fibrosis lung sputum

Analysis of Pseudomonas aeruginosa UCBPP-PA14 grown on artificial-sputum medium (ASMDM), MOPS-glucose medium and Luria broth; early exponential and stationary phases. ASMDM mimics cystic fibrosis lung environment.

Organism:: Pseudomonas aeruginosa; Pseudomonas aeruginosa UCBPP-PA14

Type:: Expression profiling by array, transformed count, 3 growth protocol, 2 time sets

Platform:: GPL84
Series:: GSE18594
8 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4250

ID:: 4250

Select item 20000390518.

Temporal Biofilm Expression of E. coli K-12 after 4, 7, 15, and 24 hr

(Submitter supplied) Temporal expression of biofilm and suspenion samples from E. coli wild type cultured on glass wool in LB medium. Samples removed after 4, 7, 15, and 24 hr of culturing Keywords: time course (temporal exression)

Organism:: Escherichia coli; Escherichia coli K-12

Type:: Expression profiling by array

Dataset:: GDS2768
Platform:: GPL199
8 Samples

Download data

Series

Accession:: GSE3905

ID:: 200003905

Select item 276819.

Escherichia coli biofilm development

Analysis of Escherichia coli K-12 biofilms up to 24 hours of culturing. Biofilm bacteria predominate in nutrient-sufficient ecosystems. Results provide insight into the molecular mechanisms underlying biofilm development.