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Links from GEO DataSets

Items: 9

1.

Early Relapse in ALL is identified by Time To Leukemia in NOD/SCID mice and is characterized by a gene signature involving survival pathways

(Submitter supplied) Gene expression analysis identified a specific signature of differentially expressed genes discriminating TTLshort and TTLlong phenotypes. Gene expression signatures of xenografted leukemia samples with different TTL phenotypes were analyzed on cohorts of pediatric BCP-ALL patients.
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS4206 GDS4779
Platform:
GPL570
209 Samples
Download data: CEL
Series
Accession:
GSE13576
ID:
200013576
2.
Full record GDS4779

NOD/SCID/huALL xenotransplant model of pediatric acute leukemia

Analysis of xenograft leukemia samples from NOD/SCID mice transplanted with leukemia cells from patients with pediatric BCP-ALL. The xenograft samples displayed short or long “Time To Leukemia” (TTL). Results provide insight into molecular mechanisms underlying the distinct TTL phenotypes.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL570
Series:
GSE13576
12 Samples
Download data: CEL
DataSet
Accession:
GDS4779
ID:
4779
3.
Full record GDS4206

Pediatric acute leukemia patients with early relapse: white blood cells

Analysis of WBCs from pediatric B cell precursor (BCP) acute lymphoblastic leukemia (ALL) patients with early, late, or no relapse. For patients with relapsed BCP-ALL, early relapses fare worse than later relapses. Results provide insight into the molecular basis of early relapses in BCP-ALL.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 disease state sets
Platform:
GPL570
Series:
GSE13576
197 Samples
Download data: CEL
DataSet
Accession:
GDS4206
ID:
4206
4.

Molecular characterization of very early relapsed childhood ALL

(Submitter supplied) Purpose: In childhood acute lymphoblastic leukemia (ALL), approximately 25% of patients suffer from relapse. In recurrent disease, despite intensified therapy, overall cure rates of 40% remain unsatisfactory and survival rates are particularly poor in certain subgroups. The probability of long-term survival after relapse is predicted from well-established prognostic factors, i. e. time and site of relapse, immunophenotype and minimal residual disease. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
60 Samples
Download data: CEL, EXP
Series
Accession:
GSE4698
ID:
200004698
5.

Acute Lymphocytic Leukemia versus associated xenografts

(Submitter supplied) Leukemic cells from either peripheral blood or bone marrow were obtained from 6 patients with acute lymphocytic leukemia. These cells were used to generate mouse xenografts and a comparison was made between those two sample sources.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6884
10 Samples
Download data: TXT
Series
Accession:
GSE15621
ID:
200015621
6.

The miR-497~195 cluster suppresses cell cycle regulators and in vivo leukemia growth in B-cell precursor Acute Lymphoblastic Leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL11154 GPL6244
22 Samples
Download data: CEL
Series
Accession:
GSE141780
ID:
200141780
7.

First bone marrow relapse with or without initial diagnosis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
113 Samples
Download data: CEL
Series
Accession:
GSE3912
ID:
200003912
8.

60 samples obtained at relapse

(Submitter supplied) Gene expression profiles were analyzed from 60 children with first bone marrow relapse. Genes and pathways differentiating early vs. late relapse were identified. Signatures predicting early response to therapy were also identified. Keywords: ordered
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
59 Samples
Download data: CEL
Series
Accession:
GSE3911
ID:
200003911
9.

35 patients at diagnosis and relapse

(Submitter supplied) 35 paired samples from initial diagnosis and first marrow relapse. Genes and pathways differentiating diagnosis and relapse were identified. Potential therapeutic targets were also identified. Keywords: paired
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
70 Samples
Download data: CEL
Series
Accession:
GSE3910
ID:
200003910
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Supplemental Content

db=gds|term=|query=11|qty=2|blobid=MCID_6735a73bb31eac71f5573884|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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