Similar studies for GEO DataSets (Select 200015852) - GEO DataSets

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Items: 16

Select item 2000158521.

Expression data from human breast tumors and their paired normal tissues

(Submitter supplied) Microarray is widely used to monitor gene expression changes in breast cancer. The transcriptomic changes in breast cancer is commonly occured during the transition of normal cells to cancerous cells. This is the first study on gene expression profiling of multi ethnic of Malaysian breast cancer patients (Malays, Chinese and Indian). We aim to identify differentially expressed genes between tumors and normal tissues. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
86 Samples

Download data: CEL, CHP

Series

Accession:: GSE15852

ID:: 200015852

Select item 2000038932.

Gene Expression Profiling of matched Ductal Carcinomas in Situ and Invasive Breast Tumors

(Submitter supplied) This is a matched-pair analysis of ductal carcinoma in situ (DCIS) and invasive component (IDC) of nine breast ductal carcinoma to identify novel molecular markers characterizing the transition from DCIS to IDC for a better understanding of its molecular biology. Keywords: Affymetrix-based Microarrays in Mamma carcinoma

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS2045 GDS2046
Platforms:: GPL570 GPL96
24 Samples

Download data

Series

Accession:: GSE3893

ID:: 200003893

Select item 20463.

Ductal carcinoma in situ to invasive ductal carcinoma progression (HG-U133 2.0)

Analysis of preinvasive ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) tumors. Pairs of patient-matched DCIS and IDC tumor specimens analyzed. Results provide insight into the mechanisms underlying the progression of DCIS to IDC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 7 individual sets

Platform:: GPL570
Series:: GSE3893
14 Samples

Download data

DataSet

Accession:: GDS2046

ID:: 2046

Select item 20454.

Ductal carcinoma in situ to invasive ductal carcinoma progression (HG-U133A)

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 5 individual sets

Platform:: GPL96
Series:: GSE3893
10 Samples

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DataSet

Accession:: GDS2045

ID:: 2045

Select item 2000132935.

Parity and the genomic signature in the Human Breast

(Submitter supplied) Case-control study for the analysis of the gene expression profile of epithelial cells microdissected from normal breast tissues obtained from 17 parous and 7 nulliparous women free of breast pathology (controls), and 39 parous and 8 nulliparous women with history of breast cancer (cases). Keywords: genetic modifications

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL7393 GPL7392 GPL7384
210 Samples

Download data: TXT

Series

Accession:: GSE13293

ID:: 200013293

Select item 2000110426.

Ductal Carcinoma Progression

(Submitter supplied) To obtain insight into the molecular basis of ductal carcinoma in situ (DCIS) and its progression by infiltrating surrounding tissue, we have performed cellular-based gene expression analysis of pure DCIS and DCIS with co-existing invasive ductal carcinoma (IDC) and compared the histological and molecular aspects between these morphologically identical lesions seeking to find key genes involved in DCIS progression. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1930
60 Samples

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Series

Accession:: GSE11042

ID:: 200011042

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000203427.

Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer

(Submitter supplied) Alternative promoters (APs) occur in >30% protein-coding genes and contribute to proteome diversity. However, large-scale analyses of AP regulation are lacking, and little is known about their potential physiopathologic significance. To better understand the transcriptomic impact of estrogens, which play a major role in breast cancer, we analyzed gene and AP regulation by estradiol in MCF7 cells using pan-genomic exon arrays. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL5175 GPL5188
32 Samples

Download data: CEL

Series

Accession:: GSE20342

ID:: 200020342

Select item 2000024298.

Atypical Ductal Hyperplasia

(Submitter supplied) Fresh Atypical ductal hyperplasia (ADH) tissue collected from breast of a women who either (1) had no prior history of breast cancer and had not developed breast cancer in five years after diagnosis, (2) had cancer before ADH, or had cancer at the time as ADH or developed cancer after ADH diagnosis Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1250
Platform:: GPL96
8 Samples

Download data: CEL, CHP

Series

Accession:: GSE2429

ID:: 200002429

Select item 12509.

Atypical ductal hyperplasia and breast cancer

Comparison of atypical ductal hyperplasia (ADH) tissues from patients with and without a history of breast cancer. Incidence of invasive breast cancer is high in ADH patients. Results identify putative markers of invasive breast cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL96
Series:: GSE2429
8 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS1250

ID:: 1250

Select item 20000957410.

Gene expression abnormalities in histologically normal breast epithelium of breast cancer patients

(Submitter supplied) Normal-appearing epithelium of cancer patients can harbor occult genetic abnormalities. Data comprehensively comparing gene expression between histologically normal breast epithelium of breast cancer patients and cancer-free controls are limited. The present study compares global gene expression between these groups. We performed microarrays using RNA from microdissected histologically normal terminal ductal-lobular units (TDLU) from 2 groups: (i) cancer normal (CN) (TDLUs adjacent to untreated ER1 breast cancers (n = 14)) and (ii) reduction mammoplasty (RM) (TDLUs of age-matched women without breast disease (n = 15)). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3139
Platform:: GPL96
29 Samples

Download data: CEL

Series

Accession:: GSE9574

ID:: 200009574

Select item 313911.

Breast cancer: histologically normal breast epithelium

Analysis of histologically normal breast epithelia of breast cancer patients. Results provide insight into the molecular abnormalities in normal appearing breast epithelium in breast cancer and the roles these abnormalities play in carcinogenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL96
Series:: GSE9574
29 Samples

Download data: CEL

DataSet

Accession:: GDS3139

ID:: 3139

Select item 20007265312.

Mapping alterations spatially and temporally during early stages of breast tumourigenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by genome tiling array

Platforms:: GPL9128 GPL6480
72 Samples

Download data: TXT

Series

Accession:: GSE72653

ID:: 200072653

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007265213.

Mapping alterations spatially and temporally during early stages of breast tumourigenesis [aCGH]

(Submitter supplied) Identifying genomic alterations that precede tumourigenesis of breast tumours will allow us to better understand tumour development and heterogeneity. In particular, by obtaining and profiling normal-epithelium samples at various distances from the tumour, we can draft both a spatial and temporal map of the genomic events and transcriptomic alterations that occur along the mammary duct (leading up to and including the tumour).

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL9128
36 Samples

Download data: TXT

Series

Accession:: GSE72652

ID:: 200072652

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007264414.

Mapping alterations spatially and temporally during early stages of breast tumourigenesis [expression]

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
36 Samples

Download data: TXT

Series

Accession:: GSE72644

ID:: 200072644

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005219415.

mRNA-sequencing of breast cancer subtypes and normal tissue

(Submitter supplied) Goal: To define the digital transcriptome of three breast cancer subtypes (TNBC, Non-TNBC, and HER2-positive) using RNA-sequencing technology. To elucidate differentially expressed known and novel transcripts, alternatively spliced genes and differential isoforms and lastly expressed variants in our dataset. Method: Dr. Suzanne Fuqua (Baylor College of Medicine) provided the human breast cancer tissue RNA samples. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
20 Samples

Download data: GTF, VCF

Series

Accession:: GSE52194

ID:: 200052194

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20002645716.

Defining the Genomic Signature of the Parous Breast

(Submitter supplied) It is widely accepted that a woman’s lifetime risk of developing breast cancer at menopause is reduced by early full term pregnancy and multiparity. This phenomenon is associated with the development and differentiation of the breast, which ultimately imprints a specific genomic profile in the mammary epithelium. In the present work we demonstrate that this profile represents a permanent signature that could be associated with the breast cancer risk reduction conferred by pregnancy. more...