GEO DataSets

(Submitter supplied) Bistable populations of bacteria give rise to two or more subtypes that exhibit different phenotypes. We have explored whether the periodontal pathogen, Porphyromonas gingivalis, exhibits bistable invasive phenotypes. Using a modified cell invasion assay, we show for the first time that there are two distinct sub-types within a population of P.ginigivalis strains NCTC 11834 and W50 that display differences in their ability to invade oral epithelial cells. more...

Organism:

Porphyromonas gingivalis

Type:

Expression profiling by array

Platform:

GPL10575

24 Samples

Download data: MEV

(Submitter supplied) The genomes of P. gingivalis strains 33277 and 381 are highly related phylogenetically. However, 33277 displays a reduced capacity to stimulate HEK cell TLR2-dependent signaling and THP-1 cell-dependent IL-1β production compared to 381, suggesting strain-specific differences in the expression of one or more bacterial immune-modulatory cell surface molecules. Genomic sequencing identified a single nucleotide polymorphism in the 33277 fimB allele (A>T), encoding a truncated FimB protein, relative to the 381 fimB allele. more...

Organism:

Porphyromonas gingivalis 381; Porphyromonas gingivalis ATCC 33277

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL26349 GPL25781

6 Samples

Download data: XLSX

(Submitter supplied) Transcriptional profiling of the wild-type and its htrA mutant. Identification of genes that are affected by the htrA mutation in P. gingivalis Keywords: Genetic modification

Organism:

Porphyromonas gingivalis

Type:

Expression profiling by array

Platform:

GPL6324

8 Samples

Download data: MEV

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Porphyromonas gingivalis

Type:

Expression profiling by array

Platform:

GPL15605

9 Samples

Download data: CSV

(Submitter supplied) Transcriptional profiling of P. gingivalis cells comparing cells grown under iron replete conditions to that grown under iron depleted conditions

Organism:

Porphyromonas gingivalis

Type:

Expression profiling by array

Platform:

GPL15605

6 Samples

Download data: CSV

(Submitter supplied) Transcriptional profiling of P. gingivalis cells comparing cells grown under hemin replete conditions to that grown under hemin depleted conditions

Organism:

Porphyromonas gingivalis

Type:

Expression profiling by array

Platform:

GPL15605

3 Samples

Download data: CSV

(Submitter supplied) The human oral pathogen Porphyromonas gingivalis colonizes the gingival crevice and invades gingival epithelial cells. Multidimensional capillary high-performance liquid chromatography coupled with tandem mass spectrometry and two-dimensional gel electrophoresis were used to analyze the proteome of P. gingivalis as it adapts to a set of experimental conditions designed to reflect important features of an epithelial cell environment. more...

Organism:

Porphyromonas gingivalis

Type:

Other

Platform:

GPL2841

1 Sample

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(Submitter supplied) This set includes 977 P. gingivalis proteins identified in this study

Organism:

Porphyromonas gingivalis

1 Series

1 Sample

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(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Haemophilus influenzae; Porphyromonas gingivalis W83; Porphyromonas gingivalis

Type:

Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:

GPL33075 GPL18755

24 Samples

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(Submitter supplied) To understand the role of CdhR and its adjacent gene PG1236 in nitric oxide (NO) stress resistance, isogenic mutants P. gingivalis FLL457 (ΔPG1237::ermF), FLL458 (ΔPG1236::ermF) and FLL459 (ΔPG1236-37::ermF) were made by allelic exchange mutagenesis and their gene expression was studied under control and NO stress conditions. DNA microarray analysis of FLL457 showed that approximately 2% of the genes were up regulated and over 1% of the genes down regulated. more...

Organism:

Porphyromonas gingivalis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33075

12 Samples

Download data: XLSX

(Submitter supplied) To understand the role of CdhR and its adjacent gene PG1236 in nitric oxide (NO) stress resistance, isogenic mutants P. gingivalis FLL457 (ΔPG1237::ermF), FLL458 (ΔPG1236::ermF) and FLL459 (ΔPG1236-37::ermF) were made by allelic exchange mutagenesis and their gene expression was studied under control and NO stress conditions. DNA microarray analysis of FLL457 showed that approximately 2% of the genes were up regulated and over 1% of the genes down regulated. more...

Organism:

Porphyromonas gingivalis W83; Haemophilus influenzae

Type:

Expression profiling by array

Platform:

GPL18755

12 Samples

Download data: XLS

(Submitter supplied) Transcriptional profiling of P. gingivalis cells comparing control cells grown in anaerobic conditions with cells grown in the presence of 6% of oxygen

Organism:

Porphyromonas gingivalis

Type:

Expression profiling by array

Platform:

GPL9149

5 Samples

Download data: GPR