GEO DataSets

(Submitter supplied) Corynebacterium glutamicum GlxR is a homolog of the cAMP receptor protein. Although over 200 GlxR binding sites in the C. glutamicum genome are predicted in silico, studies on the GlxR physiological function have been hindered by the severe growth defects of a glxR mutant. This study comprehensively identified the GlxR regulon by chromatin immunoprecipitation in conjunction with microarray (ChIP-chip) analyses. more...

Organism:

Corynebacterium glutamicum

Type:

Genome binding/occupancy profiling by array

Platform:

GPL11651

7 Samples

Download data: GPR

(Submitter supplied) DNA microarrays were applied to investigate the effect of cpdA deletion (del) or overexpression (over) on the global gene expression of C. glutamicum cells. For overexpression of cpdA the gene was cloned into plasmid pEKEx2 under control of the IPTG-inducible tac promoter, which was induced by addition of 250 µM IPTG.

Organism:

Corynebacterium glutamicum; Gluconobacter oxydans; Escherichia coli; Bacillus subtilis subsp. subtilis str. 168

Type:

Expression profiling by array

Platform:

GPL20268

6 Samples

Download data: GPR

(Submitter supplied) The cAMP-dependent transcriptional regulator GlxR serves as a central hub in the regulatory network of the actinobacterial model organism Corynebacterium glutamicum and controls expression of ~10% of all genes. The consequences of a lowered cAMP level are mostly unkown. A single gene (cyaB) for a cAMP-synthesizing adenylate cyclase was identified and it had been reported that a cyaB mutant grows like the wild type on glucose, but has a strong growth defect in the presence of acetate. more...

Organism:

Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL9860

3 Samples

Download data: GPR, XLSX

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Corynebacterium glutamicum R

Type:

Expression profiling by array; Genome binding/occupancy profiling by array

Platform:

GPL18839

8 Samples

Download data: TXT

(Submitter supplied) The transcriptional regulator GntR1 downregultates the genes for gluconate catabolism and pentose phosphate pathway in Corynebacterium glutamicum. Gluconate lowers the DNA binding affinity of GntR1, which is probably the mechanism of gluconate-dependent induction of these genes. In addition, GntR1 positively regulates the ptsG, a gene encoding for a major glucose transporter, and the pck, a gene encoding phosphoenolpyruvate carboxykinase. more...

Organism:

Corynebacterium glutamicum R

Type:

Genome binding/occupancy profiling by array

Platform:

GPL18839

2 Samples

Download data: TXT

(Submitter supplied) The transcriptional regulator GntR1 downregulates the genes for gluconate catabolism and pentose phosphate pathway in Corynebacterium glutamicum. Gluconate lowers the DNA binding affinity of GntR1, which is probably the mechanism of gluconate-dependent induction of these genes. In addition, GntR1 positively regulates the ptsG, a gene encoding for a major glucose transporter, and the pck, a gene encoding phosphoenolpyruvate carboxykinase. more...

Organism:

Corynebacterium glutamicum R

Type:

Expression profiling by array

Platform:

GPL18839

6 Samples

Download data: TXT

(Submitter supplied) <Background> The pstSCAB operon of Corynebacterium glutamicum, which encodes an ABC transport system for uptake of phosphate (Pi), is induced during the P i starvation response. The two-component regulatory system PhoRS is involved in this response, but partial Pi starvation induction of pstSCAB in a ∆phoRS mutant indicated the involvement of additional regulator(s). Regulation of pstSCAB also involves the global transcriptional regulator GlxR. more...

Organism:

Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL19905

2 Samples

Download data: CSV

(Submitter supplied) Transcriptional profiling of Corynebacterium glutamicum cells comparing wild-type cells with cg0196 deletion mutant cells by site-specific gene deletion using the non-replicable integration vector. cg0196 is gene conding transcriptional regulator related carbon metabolism.

Organism:

Corynebacterium glutamicum

Type:

Expression profiling by array

Platform:

GPL14656

1 Sample

Download data: GPR

(Submitter supplied) In summary, we have identified and characterized FtsR as a transcriptional activator of the essential cell division protein FtsZ in C. glutamicum, providing a novel regulatory player in the process of cell division.

Organism:

Escherichia coli; Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032; Bacillus subtilis subsp. subtilis str. 168; Gluconobacter oxydans

Type:

Expression profiling by array

Platform:

GPL16989

3 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Corynebacterium glutamicum R

Type:

Expression profiling by array; Genome binding/occupancy profiling by array

Platform:

GPL17881

20 Samples

Download data: TXT

(Submitter supplied) The extracytoplasmic function sigma factor SigH is responsible for heat and oxidative stress response in a biotechnologically -important bacterium Corynebacterium glutamicum. Due to the hierarchical nature of the regulatory network, it has not been possible to fully determine the SigH regulon by previous transcriptome analyses. Here, we determined the direct genome-wide targets of SigH were determined by ChIP-chip analysis using a deletion mutant of rshA, encoding an anti-sigma factor of SigH. more...

Organism:

Corynebacterium glutamicum R

Type:

Genome binding/occupancy profiling by array

Platform:

GPL17881

10 Samples

Download data: TXT

(Submitter supplied) The extracytoplasmic function sigma factor SigH is responsible for heat and oxidative stress response in a biotechnologically -important bacterium Corynebacterium glutamicum. Due to the hierarchical nature of the regulatory network, it has not been possible to fully determine the SigH regulon by previous transcriptome analyses. Here, we determined the direct genome-wide targets of SigH were determined by ChIP-chip analysis using a deletion mutant of rshA, encoding an anti-sigma factor of SigH. more...

Organism:

Corynebacterium glutamicum R

Type:

Expression profiling by array

Platform:

GPL17881

10 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Corynebacterium glutamicum; Corynebacterium glutamicum R

Type:

Expression profiling by array; Genome binding/occupancy profiling by array

Platforms:

GPL17881 GPL20864 GPL20865

14 Samples

Download data: TXT

(Submitter supplied) Bacteria modify expression of different types of terminal oxidase in response to oxygen availability. Corynebacterium glutamicum, a facultative anaerobic bacterium in Actinobacteria, possesses aa3-type cytochrome c oxidase and cytochrome bd-type quinol oxidase, the latter of which is induced upon oxygen limitation. We report here that an extracytoplasmic function sigma factor, SigC, is unprecedentedly responsible for the regulation. more...

Organism:

Corynebacterium glutamicum R

Type:

Genome binding/occupancy profiling by array

Platform:

GPL20865

4 Samples

Download data: TXT

(Submitter supplied) Bacteria modify expression of different types of terminal oxidase in response to oxygen availability. Corynebacterium glutamicum, a facultative anaerobic bacterium in Actinobacteria, possesses aa3-type cytochrome c oxidase and cytochrome bd-type quinol oxidase, the latter of which is induced upon oxygen limitation. We report here that an extracytoplasmic function sigma factor, SigC, is unprecedentedly responsible for the regulation. more...

Organism:

Corynebacterium glutamicum R; Corynebacterium glutamicum

Type:

Expression profiling by array

Platform:

GPL20864

4 Samples

Download data: TXT

(Submitter supplied) Bacteria modify expression of different types of terminal oxidase in response to oxygen availability. Corynebacterium glutamicum, a facultative anaerobic bacterium in Actinobacteria, possesses aa3-type cytochrome c oxidase and cytochrome bd-type quinol oxidase, the latter of which is induced upon oxygen limitation. We report here that an extracytoplasmic function sigma factor, SigC, is unprecedentedly responsible for the regulation. more...

Organism:

Corynebacterium glutamicum R

Type:

Expression profiling by array

Platform:

GPL17881

6 Samples

Download data: TXT

(Submitter supplied) Copper is an essential cofactor for many enzymes but at high concentrations it is toxic for the cell. Copper ion concentrations ≥50 µM inhibited growth of Corynebacterium glutamicum. The transcriptional response to 20 µM Cu2+ was studied using DNA microarrays and revealed 26 genes that showed a ≥3-fold increased mRNA level, including cg3280-cg3289. Several genes in this genomic region code for proteins presumably involved in the adaption to copper-induced stress, e. more...

Organism:

Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL9860

9 Samples

Download data: GPR

(Submitter supplied) The response regulator HrrA belonging to the HrrSA two-component system (previously named CgtSR11) is known to be repressed by the global iron-dependent regulator DtxR in Corynebacterium glutamicum. Sequence analysis indicated an involvement of the HrrSA system in heme-dependent gene expression. Growth experiments revealed that the non-pathogenic soil bacterium C. glutamicum is able to use hemin or hemoglobin as sole iron source. more...

Organism:

Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL9860

9 Samples

Download data: GPR

(Submitter supplied) We recently showed that the two-component system (TCS) HrrSA plays a central role in the control of heme homeostasis in the Gram-positive soil bacterium Corynebacterium glutamicum. Here, we characterized the function of another TCS of this organism, ChrSA, which exhibits significant sequence similarity to HrrSA, and provide evidence for cross-regulation of the two systems. In this study ChrSA was shown to be crucial for heme resistance of C. more...

Organism:

Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL15451

6 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Corynebacterium glutamicum; Corynebacterium glutamicum R

Type:

Genome binding/occupancy profiling by array; Expression profiling by array

Platforms:

GPL20864 GPL20865

22 Samples

Download data: TXT