Similar studies for GEO DataSets (Select 200062367) - GEO DataSets

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Items: 20

Select item 2000623671.

MicroRNA expression in medulloepitheliomas

(Submitter supplied) Purpose: To study the differential expression of microRNA (miRNA) profiles between intraocular medulloepithelioma (ME) and normal control tissue. Material and methods: Total RNA was extracted from formalin fixed paraffin-embedded intraocular ME (n=7) and from age matched ciliary body controls (n=8). The clinical history and phenotype was recorded. MiRNA profiles were determined using the Affymetrix® GeneChip® miRNA Arrays analyzed using expression console 1.3 software. more...

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL16384
15 Samples

Download data: CEL

Series

Accession:: GSE62367

ID:: 200062367

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000344602.

Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic naevi

(Submitter supplied) Perturbations in microRNA (miRNA) expression profiles has been reported for cutaneous malignant melanoma (CMM). With regards to a rapidly growing number of newly discovered miRNA sequences, the availability of up-to-date miRNA expression profiles for primary cutaneous malignant melanoma (PCMM), cutaneous malignant melanoma metastases (CMMM) and benign melanocytic naevi (BMN) is limited. Patients with PCMM (n=9), CMMM (n=4) and BMN (n=8) were included in the study. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL15019
21 Samples

Download data: TXT

Series

Accession:: GSE34460

ID:: 200034460

Select item 2000400493.

Deregulated microRNAs in triple-negative breast cancer revealed by deep sequencing

(Submitter supplied) Twenty-four triple-negative breast cancer and 14 adjacent normal tissues were collected from breast cancer patients during surgeries at National Taiwan University Hospital (NTUH, Taipei, Taiwan). All triple-negative breast cancer samples were invasive ductal carcinomas (IDC) and were negative in immunohistochemical statuses of ER, PR, and HER2 receptors, as confirmed by professional pathologists. Treatment procedure of all patients followed the National Comprehensive Cancer Network (NCCN) guideline. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL13393
38 Samples

Download data: TXT

Series

Accession:: GSE40049

ID:: 200040049

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000345364.

Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma

(Submitter supplied) MicroRNAs (miRNAs) are a novel class of short RNAs which have shown to be dysregulated in a variety of cancers including squamous cell carcinoma (SCC) of the head&neck. Microarray based miRNA expression profiles of cutaneous SCC (cSCC) however have not been investigated so far. Seven patients with cutaneous SCC were enrolled in the study. Tumor biopsies (n=7) were taken from the center of the tumor. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL15019
14 Samples

Download data: TXT

Series

Accession:: GSE34536

ID:: 200034536

Select item 2000711475.

MicroRNA expression proﬁling in GC-2 cells following 50 Hz ELF-EMF

(Submitter supplied) Aberrant miRNA expression has been related to the development of human germ cell tumors, but little is known about effect of ELF-EMFs on miRNA expression. ELF-EMFs may epigenetically modify cells, which may account for the adverse effects of ELF-EMFs on the male reproductive system. To identify miRNAs that were differentially expressed between the sham and ELF-EMF exposure groups, we performed an Affymetrix microarray analysis to establish the miRNA expression profiles.

Organism:: synthetic construct; Mus musculus

Type:: Non-coding RNA profiling by array

Platform:: GPL16384
3 Samples

Download data: CEL

Series

Accession:: GSE71147

ID:: 200071147

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Select item 2000297426.

MIRnome Profiling of Hereditary Pheochromocytoma and Paraganglioma Reveals Specific Signatures According to Primary Mutation: Possible Implications in the Differentiation Status of Tumor Cells

(Submitter supplied) Pheochromocytoma (PCC) and paraganglioma (PGL) are rare neuroendocrine neoplasias of neural crest origin. They can be part of several syndromes, and their mRNA profile is dependent on genetic background, but questions related to clinical behavior or even main location remain unanswered. MicroRNAs are key modulators of target genes through translational repression, mRNA degradation, or both, and therefore they could resolve some of these issues. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL8227
54 Samples

Download data: TXT

Series

Accession:: GSE29742

ID:: 200029742

Select item 2000367277.

MicroRNA Profiling in Mucosal Biopsies of Eosinophilic Esophagitis Patients Pre and Post Glucocorticoid Steroid Treatment and Relationship with mRNA Target Expression

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Expression profiling by RT-PCR

Platforms:: GPL13328 GPL6244
20 Samples

Download data: CEL

Series

Accession:: GSE36727

ID:: 200036727

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Select item 2000367268.

miRNA Profiling in mucosal biopsies of Eosinophilic Esophagitis patients pre and post glucocorticoid steroid treatment

(Submitter supplied) Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the miRNA expression changes in EoE before and after a successful glucocorticoid steroid treatment.

Organism:: Homo sapiens

Type:: Expression profiling by RT-PCR

Platform:: GPL13328
10 Samples

Download data: TXT

Series

Accession:: GSE36726

ID:: 200036726

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Select item 2000367259.

Gene profiling in mucosal biopsies of Eosinophilic Esophagitis patients pre and post glucocorticoid steroid treatment

(Submitter supplied) Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the gene expression changes in EoE before and after a successful glucocorticoid steroid treatment. We used microarrays to identify distinct genes involving the pathophysiology of EoE.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
10 Samples

Download data: CEL

Series

Accession:: GSE36725

ID:: 200036725

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Select item 20005940110.

Gene expression profiles of rat enamel organs (secretory--stage and maturation stage)

(Submitter supplied) We conducted the genome-wide mRNA expression profiling in parallel with miRNA expression profiling using RNA samples extracted from rat incisor enamel organs, so as to refine the number of predicted gene targets for miRNA regulators.

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL6101
8 Samples

Download data: TXT

Series

Accession:: GSE59401

ID:: 200059401

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Select item 20008474711.

RETINOBLASTOMA MICRORNA LANDSCAPE

(Submitter supplied) In this work we examined miRNome expression in 12 samples of retinoblastoma. Present miRNAs show the common working machinery with Rb affecting most of pathways considered hallmarks of cancer.

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL21572
12 Samples

Download data: CEL, CHP, TXT

Series

Accession:: GSE84747

ID:: 200084747

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Select item 20006086112.

An integrative analysis of renal miRNA- and mRNA-expression signatures in progressive chronic kidney disease

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platform:: GPL13497
72 Samples

Download data: TXT

Series

Accession:: GSE60861

ID:: 200060861

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Select item 20006086013.

An integrative analysis of renal miRNA- and mRNA-expression signatures in progressive chronic kidney disease [validation cohort]

(Submitter supplied) MicroRNAs (miRNAs) contribute to chronic kidney disease progression via negatively regulating mRNA abundance. However, their association with clinical outcome remains poorly understood. We performed large-scale miRNA and mRNA expression profiling on cryo-cut renal biopsy sections from a discovery (n=43) and a validation (n=29) cohort. In the discovery cohort (GEO Series accession number GSE45980), miRNAs differentiating stable and progressive cases were determined, and putative target mRNAs showing inversely correlated expression profiles were identified. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platform:: GPL13497
29 Samples

Download data: TXT

Series

Accession:: GSE60860

ID:: 200060860

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Select item 20004598014.

An integrative analysis of renal miRNA- and mRNA-expression signatures in progressive chronic kidney disease [discovery cohort]

(Submitter supplied) MicroRNAs (miRNAs) significantly contribute to chronic kidney disease (CKD) progression via regulating mRNA expression and abundance. However, their association with clinical outcome remains poorly understood. We performed large scale miRNA and mRNA expression profiling on cryo-cut renal biopsy sections from n=43 subjects. miRNAs differentiating stable and progressive cases were determined, and putative target mRNAs showing inversely correlated expression profiles were identified and further characterized. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platform:: GPL13497
43 Samples

Download data: TXT

Series

Accession:: GSE45980

ID:: 200045980

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Select item 20003453515.

Microarray analysis of microRNA expression in basal cell carcinoma

(Submitter supplied) Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC (n=7) were included in the study. Punch biopsies were harvested from the center of the tumors (lesional, n=7) and from sites of adjacent non-lesional skin (intraindividual control, n=7). more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL15019
14 Samples

Download data: TXT

Series

Accession:: GSE34535

ID:: 200034535

Select item 20004895916.

Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL14613 GPL6244
48 Samples

Download data: CEL

Series

Accession:: GSE48959

ID:: 200048959

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Select item 20004895817.

Mucosal gene expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
21 Samples

Download data: CEL

Series

Accession:: GSE48958

ID:: 200048958

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Select item 20004895718.

Mucosal miRNA expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
27 Samples

Download data: CEL

Series

Accession:: GSE48957

ID:: 200048957

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002176719.

MicroRNA expression profiling on formalin-fixed paraffin-embedded (FFPE) tissue blocks of human adrenal pheochromocytomas

(Submitter supplied) MicroRNAs are involved in the pathogenesis of several tumors, however, there have been no data on microRNA expression in pheochromocytomas to date. In this study we have performed microRNA expression profiling in sporadic benign, hereditary benign (multiplex endocrine neoplasia type 2-related and von Hippel-Lindau syndrome-related pheochromocytomas), and sporadic recurring adrenomedullary tumors. Due to the rarity of these neoplasms, the retrieval of sufficient quantities of fresh or immediately snap frozen tumor samples is difficult, therefore the applicability of formalin-fixed paraffin-embedded tissue samples for the analysis of microRNA expression in pheochromocytomas was examined.