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Effect of Gfi1 36N variant on genome-wide H3K9 Acetylation patterns
PubMed Similar studies SRA Run Selector
Epigenetic therapy as a novel approach for GFI136N-associated AML
Genome-wide maps of chromatin state in bone marrow cells
PubMed Full text in PMC Similar studies SRA Run Selector
Trancriptomic analysis of leukemic bone marrow cells with GFI1 wildtype, GFI1 SNP variant (GFI1-36N) and low level of GFI1 expression
PubMed Full text in PMC Similar studies
Gfi1 as a new predictive and therapeutical target of MDS/AML
The Growth factor independence 1 (GFI1) 36N variant predisposes to Acute Myeloid Leukemia (AML) by inducing epigenetic changes at the Hoxa9 locus
Gene expression profiles of MV-4-11 AML cells treated HDAC1/2 -selective inhibitor and Azacitidine
PubMed Full text in PMC Similar studies Analyze with GEO2R
ATACseq analysis of granulocyte-monocyte progenitor cells (GMPs) with GFI1 wildtype and low level of GFI1 expression
PubMed Similar studies
LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML
GFI1 is pivotal for AML1-ETO positive acute myeloid leukemia
Inhibitors of LSD1 target demethylase-independent activity to induce differentiation in acute myeloid leukemia [anti-H3K9 ac, anti-H3K27, RCOR1, SPI1, and MLL4 ChIP-Seq]
Inhibitors of LSD1 target demethylase-independent activity to induce differentiation in acute myeloid leukemia [ATAC-Seq]
Inhibitors of LSD1 target demethylase-independent activity to induce differentiation in acute myeloid leukemia [anti-LSD1, MYB, and GFI1 ChIP-Seq]
Inhibitors of LSD1 target demethylase-independent activity to induce differentiation in acute myeloid leukemia
Inhibitors of LSD1 target demethylase-independent activity to induce differentiation in acute myeloid leukemia [ChIP-Seq: histone modifications]
Inhibitors of LSD1 target demethylase-independent activity to induce differentiation in acute myeloid leukemia [RNA-Seq experiments]
PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector
Differential gene expression profiling by deletion of GFI1 super-enhancer (GFI1-SE-KO) upon treatment of a LSD1 inhibitor NCD38 in HEL cells
PubMed Similar studies Analyze with GEO2R
Single-cell RNA-seq of AML patient bone marrow treated with INCB059872, azacitidine, or combination
Single-cell RNA-seq: INCB059872 in wild-type murine bone marrow
RNA-seq of murine megakaryocyte progenitor cells treated with LSD1 inhibitor INCB059872
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