Similar studies for GEO DataSets (Select 200084641) - GEO DataSets

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Items: 20

Select item 2000846411.

Evaluation of ccpA deletion on global gene expression of three M serotype strains of group A streptococcus

(Submitter supplied) We sought to determine how deletion of ccpA affects the gene expression profile in three M serotype strains of group A streptococcus

Organism:: Streptococcus sp. 'group A'

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19691
24 Samples

Download data: TXT

Series

Accession:: GSE84641

ID:: 200084641

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Select item 2000113282.

MGAS5005 vs MGAS5005∆ccpA

(Submitter supplied) The aim of this study was to determine the extent of the CcpA regulon in the M1 serotype MGAS5005. Kinkel and McIver, 2008 Infection and Immunity Keywords: group A streptococcus, CcpA

Organism:: Streptococcus pyogenes

Type:: Expression profiling by array

Platform:: GPL1482
6 Samples

Download data: GPR

Series

Accession:: GSE11328

ID:: 200011328

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Select item 2000101563.

Analysis of the group A Streptococcus CcpA Transcriptome

(Submitter supplied) This study evaluate how catabolite control protein A (CcpA) inactivation affected gene transcript levels in the group A Streptococcus serotype M1 strain MGAS5005 during growth in standard laboratory medium. Keywords: transcriptome analysis

Organism:: Streptococcus pyogenes; Streptococcus sp. 'group A'

Type:: Expression profiling by array

Platform:: GPL6186
16 Samples

Download data: CEL

Series

Accession:: GSE10156

ID:: 200010156

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Select item 2000252534.

Expression profiling of S. pyogenes in response to Glucose and mutation of the regulators CcpA and LacD.1

(Submitter supplied) Transcriptome changes were measured in S. pyogenes strain HSC5 in response to glucose availability, taking samples from the wild type strain (HSC5) grown in carbohydrate poor medium (C medium) versus this same medium with 1% (w/v) Glucose added. Furthermore, the effects of deletion of glucose responsive regulators CcpA and LacD.1 were measured by using isogenic mutants in these genes (Delta CcpA and Delta LacD.1 respectively) compared to the wild type parent strain (HSC5), both grown in C medium with 1% glucose.

Organism:: Streptococcus pyogenes

Type:: Expression profiling by array

Platform:: GPL11190
12 Samples

Download data: TXT

Series

Accession:: GSE25253

ID:: 200025253

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Select item 2000126145.

Analysis of the CcpA regulon in Staphylococcus aureus

(Submitter supplied) Background The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram positive bacteria. It functions as a catabolite repressor or activator, allowing the bacteria to utilize the preferred carbon source over secondary carbon sources. This study is the first CcpA-dependent transcriptome and proteome analysis in S. more...

Organism:: Staphylococcus aureus; Staphylococcus aureus subsp. aureus str. Newman

Type:: Expression profiling by array

Platform:: GPL3931
6 Samples

Download data

Series

Accession:: GSE12614

ID:: 200012614

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Select item 2000202126.

Comparison of the CcpA and CovR Transcriptomes in Group A Streptococcus

(Submitter supplied) The goal of this study were to compare the transcriptoms of CcpA and CovR in group A Streptococcus. Isogenic mutant strains were created in which CcpA and CovR were inactivated alone and in combination. The transcriptomes of the four strains (wild-type, CcpA mutant, CovR mutant, and ccpA-covR double mutant) were then compared.

Organism:: Streptococcus sp. 'group A'; Streptococcus pyogenes

Type:: Expression profiling by array

Platform:: GPL9080
32 Samples

Download data: CEL

Series

Accession:: GSE20212

ID:: 200020212

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Select item 2000113887.

M1 MGAS5005 TrxR+ vs. TrxR- mutant

(Submitter supplied) The aim of this study was to determine the extent of the trxR regulon in the M1 serotype MGAS5005. Gold, Leday, McIver 2008 Keywords: Wild-type vs trxR-

Organism:: Streptococcus pyogenes

Type:: Expression profiling by array

Platform:: GPL1482
6 Samples

Download data: GPR

Series

Accession:: GSE11388

ID:: 200011388

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Select item 2000675338.

Transcriptome study of the covS-regulation of a Group A Streptococcus pyogenes M23ND

(Submitter supplied) We investigated the covS-regulation of S. pyogenes in a hypervirulent M23 strain using RNA-sequencing. The differential gene expression comparison between the covS- mutant and isogenic wild type covS+ identified altered expression of 349 (18%) genes, including a broad spectrum of virulence genes and diverse metabolic genes. The data showed that the strain achieved hypervirulence by enhancing the expression of genes responsible for invasiveness and antiphagocytosis (i.e., hasABC), by abrogating the expression of toxic genes (i.e., speB), and by compromising gene products with dispensable functions (i.e., sfb1). more...

Organism:: Streptococcus pyogenes

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19982
8 Samples

Download data: XLS

Series

Accession:: GSE67533

ID:: 200067533

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Select item 2000652269.

Evaluation of covS polymorphisms on group A streptococcal global gene expression

(Submitter supplied) We sought to determine how single amino acid changes in the active site of CovS autophosphorylation and subsequent phosphorylation of the response regulator CovR affect the gene expression profile of group A streptococcus

Organism:: Streptococcus sp. 'group A'

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19691
24 Samples

Download data: TXT

Series

Accession:: GSE65226

ID:: 200065226

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Select item 20012131310.

Evaluating the effect of CovR phosphorylation on group A streptococcus global gene expression

(Submitter supplied) We sought to determine how CovRS mutations varying CovR phosphorylation levels affect the gene expression profile of group A streptococcus

Organism:: Streptococcus sp. 'group A'

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19691
32 Samples

Download data: TXT

Series

Accession:: GSE121313

ID:: 200121313

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Select item 20003039711.

GAS M49: wild type vs Δralp3 mutant

(Submitter supplied) GAS is a highly virulent Gram-positive bacterium. For the successful infection GAS express many virulence factors, which are clustered together with transcriptional regulators in distinct genomic regions. Ralp3 is a central regulator of the ERES region. In this study, we investigated the role of Ralp3 in GAS pathogenesis. To characterize the Ralp3 regulatory function on the whole genome level, GAS M49 wild type and Äralp3 mutant strains were comprehensively compared by two colour microarray analysis. more...

Organism:: Streptococcus pyogenes M49 591; Streptococcus pyogenes NZ131

Type:: Expression profiling by array

Platform:: GPL13816
16 Samples

Download data: TXT

Series

Accession:: GSE30397

ID:: 200030397

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Select item 20013320312.

Polymorphisms in RocA contribute to the molecular pathogenesis of serotype M28 group A streptococcus

(Submitter supplied) RNA-seq experiments of serotype M28 group A streptococcus strains with mutations in rocA at two time points

Organism:: Streptococcus pyogenes

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24880
257 Samples

Download data: XLSX

Series

Accession:: GSE133203

ID:: 200133203

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Select item 20011860913.

RocA has serotype-specific gene regulatory and pathogenesis activity in serotype M28 group A streptococcus

(Submitter supplied) RNA-seq experiments of a wild-type and isogenic rocA deletion mutant serotype M28 group A streptococcus strain at two time points

Organism:: Streptococcus pyogenes

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24880
12 Samples

Download data: XLSX

Series

Accession:: GSE118609

ID:: 200118609

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Select item 20003515214.

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Clostridioides difficile

Type:: Expression profiling by array

Platform:: GPL10556
16 Samples

Download data: GPR

Series

Accession:: GSE35152

ID:: 200035152

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Select item 20003507315.

Clostridium difficile mutant ccpA CD630E JIR8094: growth 10h with 0.5% glucose in TY vs growth 10h in TY

(Submitter supplied) transcriptionnal profiling of a ccpA mutant of C. difficile strain JIR8094 comparing growth 10h in 0.5% TY medium with growth 10h in TY medium

Organism:: Clostridioides difficile

Type:: Expression profiling by array

Platform:: GPL10556
8 Samples

Download data: GPR

Series

Accession:: GSE35073

ID:: 200035073

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Select item 20003507216.

Clostridium difficile CD630E JIR8094: growth 10h with 0.5% glucose in TY vs growth 10h in TY

(Submitter supplied) transcriptionnal profiling of a C. difficile strain JIR8094 comparing growth 10h in 0.5% TY medium with growth 10h in TY medium

Organism:: Clostridioides difficile

Type:: Expression profiling by array

Platform:: GPL10556
8 Samples

Download data: GPR

Series

Accession:: GSE35072

ID:: 200035072

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Select item 20003507117.

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY.

(Submitter supplied) Transcriptionnal profiling of C. difficile 630E JIR8094 strain vs a ccpA mutant after 10h of growth in TY

Organism:: Clostridioides difficile

Type:: Expression profiling by array

Platform:: GPL10556
8 Samples

Download data: GPR

Series

Accession:: GSE35071

ID:: 200035071

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Select item 20003507018.

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY with 0.5% glucose.

(Submitter supplied) Transcriptionnal profiling of C. difficile 630E JIR8094 strain vs a ccpA mutant after 10h of growth in TY with 0.5% glucose

Organism:: Clostridioides difficile

Type:: Expression profiling by array

Platform:: GPL10556
16 Samples

Download data: GPR

Series

Accession:: GSE35070

ID:: 200035070

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Select item 20003497119.

ccpA Chromatin immunoprecipitation on chip of JIR8094 (CD630E) WT strain and a ccpA mutant after 6h of growth in TY

(Submitter supplied) Comparison of ccpA Chromatine immunoprecipitation on chip using 2 strains : JIR8094 (CD630E) wild type strain and a ccpA mutant after 6h of growth in TYG. This experimental procedure was designed to investigate the consensus binding site, CRE, of pleiotropic regulator ccpA.