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Links from GEO DataSets

Items: 19

1.

Sub-chronic pulmonary transcriptional response to a mixture of 4 PAHs in adult male MutaTMMouse.

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
18 Samples
Download data: TXT
Series
Accession:
GSE87688
ID:
200087688
2.

Sub-chronic pulmonary transcriptional response to mixtures of polycyclic aromatic hydrocarbons (PAHs)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
57 Samples
Download data: TXT
Series
Accession:
GSE87691
ID:
200087691
3.

Sub-chronic pulmonary transcriptional response to coal tar, a PAH-containing complex mixture, in adult male MutaTMMouse.

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
20 Samples
Download data: TXT
Series
Accession:
GSE87690
ID:
200087690
4.

Sub-chronic pulmonary transcriptional response to a mixture of 8 polycyclic aromatic hydrocarbons in adult male MutaTMMouse.

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
19 Samples
Download data: TXT
Series
Accession:
GSE87689
ID:
200087689
5.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to 7 individual PAHs in the lung, liver, and forestomach tissues

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
371 Samples
Download data: TXT
Series
Accession:
GSE51321
ID:
200051321
6.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to indeno(123,cd)pyrene in lung, liver, and forestomach tissues [IP]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
58 Samples
Download data: TXT
Series
Accession:
GSE51320
ID:
200051320
7.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to dibenz(ah)anthracene in lung and forestomach tissues [DBahA]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
38 Samples
Download data: TXT
Series
Accession:
GSE51319
ID:
200051319
8.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to chrysene in lung, liver, and forestomach tissues [Chr]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
56 Samples
Download data: TXT
Series
Accession:
GSE51318
ID:
200051318
9.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benzo(k)fluoranthene in lung, liver, and forestomach tissues [BkF]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
42 Samples
Download data: TXT
Series
Accession:
GSE51317
ID:
200051317
10.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benzo(ghi)perylene in lung, liver, and forestomach tissues [BghiP]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
60 Samples
Download data: TXT
Series
Accession:
GSE51316
ID:
200051316
11.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benzo(b)fluoranthene in lung, liver, and forestomach tissues [BbF]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
59 Samples
Download data: TXT
Series
Accession:
GSE51315
ID:
200051315
12.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benz(a)anthracene in lung, liver, and forestomach tissues

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
58 Samples
Download data: TXT
Series
Accession:
GSE51314
ID:
200051314
13.

Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

(Submitter supplied) The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH mixtures (coal tar, diesel particulate and cigarette smoke condensate) using a two stage, FVB/N mouse skin tumor model. DBC (4 nmol) was most potent, reaching 100% tumor incidence with a shorter latency to tumor formation, less than 20 weeks of 12-O-tetradecanoylphorbol-13-acetate (TPA) promotion compared to all other treatments. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
25 Samples
Download data: TXT
Series
Accession:
GSE39455
ID:
200039455
14.

Coupling genome-wide transcriptomics and developmental toxicity profiles in zebrafish to characterize polycyclic aromatic hydrocarbon (PAH) hazard

(Submitter supplied) Polycyclic Aromatic Hydrocarbons (PAHs) are diverse environmental pollutants associated with adverse human health effects. Many studies focus on the carcinogenic effects of a limited number of PAHs and there is an increasing need to understand mechanisms of developmental toxicity of more varied yet environmentally relevant PAHs. A previous study characterized the developmental toxicity of 123 PAHs in zebrafish. more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23274
72 Samples
Download data: CSV
Series
Accession:
GSE156656
ID:
200156656
15.

Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures

(Submitter supplied) In this study, we compare genomic signature safter treatment ofprimary human bronchial epithelial cells (HBEC) cultured in 3D with polycyclic aromatic hydrocarbons (PAHs) and identify genesets predictive of cancer risk.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
29 Samples
Download data: TXT
16.

Benzo[a]pyrene and dibenzo[def,p]chrysene in 3D primary human bronchial epithelial cells [RNA-seq]

(Submitter supplied) In this study, we assess potential differences in mechanism of action for two PAHs, benzo[a]pyrene (BAP) and dibenzo-[def,p]chrysene (DBC), in a primary human 3D bronchial epithelial culture (HBEC) model based on short-term biosignatures identified from global transcriptional profiling.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
12 Samples
Download data: TXT
17.

Gene expression in C57BL/6 mice intratracheally instilled with Printex 90 carbon black nanoparticles

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL4134
97 Samples
Download data: TXT
Series
Accession:
GSE35284
ID:
200035284
18.

Pulmonary gene expression in C57BL/6 mice intratracheally instilled with Printex 90 carbon black nanoparticles

(Submitter supplied) We investigated pulmonary mRNA profiles of female mice exposed to 0.018, 0.054 and 0.162 mg Printex 90 carbon black nanoparticles by single intra-tracheal instillation. We examined responses to these doses 1, 3 and 28 days after exposure, alongside respective controls. This study demonstrates widespread changes in inflammatory and acute phase response genes that persisted to 28 days at the highest exposure dose. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL4134
67 Samples
Download data: TXT
Series
Accession:
GSE35193
ID:
200035193
19.

Hepatic gene expression in C57BL/6 mice intratracheally instilled with Printex 90 carbon black nanoparticles

(Submitter supplied) We investigated hepatic mRNA profiles of female mice exposed to 0.162 mg Printex 90 carbon black nanoparticles by single intra-tracheal instillation. We examined responses to this dose 1, 3 and 28 days after exposure, alongside respective controls. We show that genes part of the 3-hydroxy-3-methyl-glutaryl-CoA reductase pathway to be up-regulated by exposure to Printex 90.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL4134
30 Samples
Download data: TXT
Series
Accession:
GSE35192
ID:
200035192
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