GEO DataSets

(Submitter supplied) Whole blood was collected as part of monthly veterinary checkups of bottlenose dolphins housed at Dolphing Quest in Waikoloa, Hawaii, USA. Gene expression from 5 samples was analyzed for comparison to the blood transcriptome of the beluga whale.

Organism:

Tursiops truncatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL21538

5 Samples

Download data: FASTA, XLSX

(Submitter supplied) Whole blood was collected as part of annual health assessments of beluga whales from the healthy Bristol Bay, Alaska stock during 2012-2014. Gene expression from 24 animals (8 from each year) was analyzed to establish baseline information on the content and variation of the beluga whale blood transcriptome.

Organism:

Delphinapterus leucas

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23455

24 Samples

Download data: FASTA, XLSX

(Submitter supplied) Four captive bottlenose dolpins housed in Kona, Hawaii, were serially sampled at approximately monthly intervals over the course of one year, in order to establish baseline information on the content and variation of the dolphin blood transcriptome.

Organism:

Tursiops truncatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL21538

31 Samples

Download data: FASTA, PDF, XLS, XLSX

(Submitter supplied) Common bottlenose dolphins serve as sentinels for the health of their coastal environments as they are susceptible to health impacts from anthropogenic inputs through both direct exposure and food web magnification. Remote biopsy samples have been widely used to reveal contaminant burdens in free-ranging bottlenose dolphins, but do not address the health consequences of this exposure. To gain insight into whether remote biopsies can also identify health impacts associated with contaminant burdens, we employed RNA sequencing (RNA-seq) to interrogate the transcriptomes of remote skin biopsies from 116 bottlenose dolphins from the northern Gulf of Mexico and southeastern U.S. more...

Organism:

Tursiops truncatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL21538

116 Samples

Download data: TXT, XLSX

(Submitter supplied) As apex predators, cetaceans are recognized as sentinels for the health of marine ecosystems. The ability to identify the impacts of anthropogenic contamination on the health of a species requires long term monitoring to establish baseline health parameters. This makes health measurements that can be sampled from free ranging animals highly desirable. In the current study, we investigate the utility of skin gene expression profiling to monitor the physiological, health, and contaminant exposure status in bottlenose dolphins. more...

Organism:

Tursiops truncatus

Type:

Expression profiling by array

Platform:

GPL18797

94 Samples

Download data: TXT

(Submitter supplied) Archived blood samples collected during common bottlenose dolphin health assessments in the northern Gulf of Mexico from 2013 to 2018 were analyzed by RNA-seq to support and enhance the assessment of animal health. The transcriptomic data were analyzed in conjunction with the substantial pool of health and environmental data collected during health assessments to investigate the utility of transcriptomic data in overall assessment of dolphin health and/or as markers of specific health concerns.

Organism:

Tursiops truncatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL27600

76 Samples

Download data: XLSX

(Submitter supplied) To assess the impact of emerging contaminats on dolphin transcriptome

Organism:

Tursiops truncatus

Type:

Expression profiling by array

Platform:

GPL17696

8 Samples

Download data: TXT

(Submitter supplied) The goal of this study is to compare NGS-derived transcriptome profiling (RNA-seq) from three tissues of L. boringii between two critical periods of the spine growth cycle, and to identify potential genes regulating the seasonal development of nuptial spines in L. boringii. We obtained 94,900 unigenes and 2,131 differentially expressed genes among three tissues between two different spine growh periods. more...

Organism:

Leptobrachium boringii

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22593

18 Samples

Download data: FASTA, TXT

(Submitter supplied) Here we provided the first single-base resolution DNA methylatome in chicken lungs by whole-genome bisulfite sequencing (MethylC-seq). In addition, two genetically distinct highly inbred chicken lines, Leghorn and Fayoumi, were used to examine how DNA methylation regulates mRNA gene expression between two lines. The methylation profile demonstrated that methylcytosines in the chicken were more likely to occur in CG dinucleotides than in non-CG sites. more...

Organism:

Gallus gallus

Type:

Methylation profiling by high throughput sequencing

Platform:

GPL9385

2 Samples

Download data: TXT

(Submitter supplied) Analysis of gene expression changes during mouse salivary gland development using RNA-Seq

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17021

13 Samples

Download data: CSV

(Submitter supplied) Vitiligo Blood Transcriptomics Provides New Insights into Disease Mechanisms and Identifies Potential Novel Therapeutic Targets Abstract Background: Significant gaps remain regarding the pathomechanisms underlying the autoimmune response in vitiligo (VL), where the loss of self-tolerance leads to the targeted killing of melanocytes. Specifically, there is incomplete information regarding alterations in the systemic environment that are relevant to the disease state. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL8300

14 Samples

Download data: CEL

(Submitter supplied) In this study we aimed to assess technical variability associated with globin depletion in addition to assessing general technical variability in RNA-Seq from whole blood derived samples. We compared technical and biological replicates having undergone globin depletion or not and found that globin depletion removed approximately 80% of globin transcripts, improved the correlation of technical replicates, allowed for reliable detection of thousands of additional transcripts and generally increased transcript abundance measures.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL11154

47 Samples

Download data: TXT

(Submitter supplied) oligo-dT and random primed RNA-seq libraries were used to test an improved annotation of the zebrafish transcriptome

Organism:

Danio rerio

Type:

Expression profiling by high throughput sequencing

Platform:

GPL14875

12 Samples

Download data: CSV

(Submitter supplied) Background: In bovines, the development and growth of skeletal muscle involves many physiological processes and plays an extremely important role in the quality of beef, however, the regulatory mechanisms underlying the differences in meat quality are largely unknown. Therefore, a cattle muscle transcriptome analysis was performed to compare gene expression profiles between embryonic stage and adult stage. more...

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19172

6 Samples

Download data: XLSX

(Submitter supplied) We examined gene expression differences associated with changes in light cycle in Drosophila montana

Organism:

Drosophila montana

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18881

12 Samples

Download data: TXT

(Submitter supplied) Purpose: Next-generation sequencing (NGS) was used to select genes potentially associated with exercise adaptation in Arabian horses. Methods: Whole transcriptome profiling of blood was performed for untrained horses and horses from which samples were collected during at 3 different periods of training procedure (T1-during intense training period - March, T2- before starts - May and T3 -after flat racing season - October). more...

Organism:

Equus caballus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22019

37 Samples

Download data: CSV

(Submitter supplied) An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from skin samples of beluga whales, Maui's dolphin, and humpback whale. Tissue: Skin

Organism:

Balaenoptera musculus; Megaptera novaeangliae; Homo sapiens; Physeter catodon; Delphinapterus leucas; Mus musculus; Rattus norvegicus; Cephalorhynchus hectori maui

Type:

Methylation profiling by genome tiling array

Platform:

GPL28271

143 Samples

Download data: IDAT

(Submitter supplied) The goal of this study was to conduct an in-depth analysis of the human placental transcriptome. RNA was extracted from 16 placental samples using TRIzol following the manufacturer’s protocol. All samples were spiked with 96 External RNA Controls Consortium (ERCC) ExFold RNA transcripts. Ribosomal RNAs were depleted from samples using Ribo-Zero Gold and sequencing libraries were prepared using Illumina TruSeq Stranded Total RNA Sample Preparation kits. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16791

16 Samples

Download data: CSV

(Submitter supplied) Metformin is a commonly used antihyperglycaemic agent for the treatment of type 2 diabetes. Nevertheless, the exact mechanisms of action, underlying the various therapeutic effects of metformin, remain elusive. The goal of this study was to evaluate the alterations in longitudinal whole-blood transcriptome profiles of healthy individuals after a one-week metformin intervention in order to identify the novel molecular targets and further prompt the discovery of predictive biomarkers of metformin response. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17303

74 Samples

Download data: TXT

(Submitter supplied) Purpose: The aim of this study was to evaluate the effect of essentail oil dietary supplementation on gene expression in liver and muscle tissue.

Organism:

Ovis aries

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24603

32 Samples

Download data: TXT