Similar studies for GEO DataSets (Select 200100369) - GEO DataSets

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Items: 19

Select item 2001003691.

SYSTEMS ANALYSIS OF THE LIVER TRANSCRIPTOME IN ADULT MALE ZEBRAFISH EXPOSED TO THE NON-IONIC SURFACTANT NONYLPHENOL (NP).

(Submitter supplied) We report the effects of exposure to the endocrine disruptor nonylphenol (NP) on transcriptome modification in the livers of in vivo Zebrafish. Our data indicate changes in fatty acid metabolism and inflammation, pathways associated with the development of Non-Alcoholic Fatty Liver Disease (NAFLD).

Organism:: Danio rerio

Type:: Expression profiling by high throughput sequencing

Platform:: GPL15583
6 Samples

Download data: TXT

Series

Accession:: GSE100369

ID:: 200100369

PubMed Similar studies SRA Run Selector

Select item 2000010832.

Alterations in gene expression in FVB/NJ mouse liver following 4-nonylphenol (4-NP) treatment for 32 weeks

(Submitter supplied) Alterations in gene expression in FVB/NJ mouse liver following 4-nonylphenol (4-NP) treatment for 32 weeks. Mice were treated with 45 mg/kg/day 4-NP for 32 weeks, livers excised and differential gene expression determined. Samples 1 and 2 are controls and samples 3 and 4 are mice treated with 4-NP. Arrays were visualized from the K-screen, and analyzed and quantified with a phosphoimager (Molecular Imager FX, Bio-Rad, Hercules, CA) and the ResGen PathwaysTM Universal Microarray Analysis SoftwareTM (Research Genetics, Carlsbad, CA). more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS677
Platform:: GPL144
4 Samples

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Series

Accession:: GSE1083

ID:: 200001083

Select item 6773.

4-nonylphenol effect on liver

Analysis of FVB/NJ liver treated with 45 mg/kg/day 4-nonylphenol (4-NP) for 32 weeks. 4-NP is an industrial waste and elicits estrogen-like responses. Results provide insight into molecular events altered by 4-NP.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL144
Series:: GSE1083
4 Samples

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DataSet

Accession:: GDS677

ID:: 677

Select item 2001003674.

SYSTEMS ANALYSIS OF THE LIVER TRANSCRIPTOME IN ADULT MALE ZEBRAFISH EXPOSED TO THE PLASTICIZER (2-ETHYLHEXYL) PHTHALATE (DEHP).

(Submitter supplied) We report the effects of exposure to the endocrine disurptor (2-ethylhexyl) phthalate (DEHP) on transcriptome modification in the livers of in vivo Zebrafish. Our data indicate changes in fatty acid metabolism and insulin resistance, pathways associated with the development of Non-Alcoholic Fatty Liver Disease (NAFLD).

Organism:: Danio rerio

Type:: Expression profiling by high throughput sequencing

Platform:: GPL15583
6 Samples

Download data: TXT

Series

Accession:: GSE100367

ID:: 200100367

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001082275.

Hepatic transcriptomic profiles in zebrafish exposed to surface water with pollution gradients and different industrial discharge - Part2

(Submitter supplied) To assess the impact of surface water across the Hun River, several sampling sites located in the mainstream and the tributary were selected representative of pollution gradient and different pollution source. Male adult zebrafish were exposed to surface water from seven sites for 4 days. The obiectives of the study was to evaluate the ability of transcriptomic profiles exposed to surface water to determine the potential biological effects, to differentiate different pollution source, and to identify the toxic components.

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL14664
8 Samples

Download data: TXT

Series

Accession:: GSE108227

ID:: 200108227

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000923306.

Hepatic transcriptomic profiles in zebrafish exposed to surface water with pollution gradients and different industrial discharge

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL14664
8 Samples

Download data: TXT

Series

Accession:: GSE92330

ID:: 200092330

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000387267.

Toxicity of atrazine and nonylphenol in juvenile rainbow trout (Oncorhynchus mykiss): Effects on general health, disease susceptibility and gene expression

(Submitter supplied) Atrazine (ATZ) and nonylphenol (NP) are commonly identified contaminants in aquatic habitats; however, relatively few studies have considered the impact of these endocrine disrupters on immune function. This study examined the immunotoxicological effects of ATZ and NP at multiple levels of biological organization. Juvenile rainbow trout (Oncorhynchus mykiss) were exposed to a solvent control (0.00625 % v/v anhydrous ethanol), 59 µg/L ATZ, 555 µg/L ATZ, 2.3 µg/L NP or 18 µg/L NP (measured concentrations) for 4 d. more...

Organism:: Oncorhynchus mykiss; Salmo salar

Type:: Expression profiling by array

Platform:: GPL8904
24 Samples

Download data: TXT

Series

Accession:: GSE38726

ID:: 200038726

Select item 2000072208.

Microarray analysis in the zebrafish liver and telencephalon after exposure to low concentration of 17a-EE2

(Submitter supplied) Experiment exposed adult male zebrafish to 10ng/L 17-alpha ethinylestradiol for three weeks. Gene expression profiling of liver and telencephalon following exposure. Keywords: estrogenic exposure

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL3548
8 Samples

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Series

Accession:: GSE7220

ID:: 200007220

Select item 2000676009.

Differential hepatic gene expression in zebrafish (Danio rerio) exposed to the fungicide chlorothalonil reveals estrogenicity

(Submitter supplied) Chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile) is a broad spectrum fungicide used extensively in agricultural crops . The aim of this study is to analyse the effects of Chorothalonil on the gene expression profiles in zebrafish (Danio rerio), exposed to two concentrations of the fungicide in the water. Nominal concentrations were 1) Low 0.007mg/l (environmentally relevent) and 2) High 0.035mg/ml . more...

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL14688
15 Samples

Download data: TXT

Series

Accession:: GSE67600

ID:: 200067600

Select item 20011227210.

Development of gene expression signatures during fasting and refeeding (compensatory growth) for zebrafish liver

(Submitter supplied) Here, we certified zebrafish to be a suitable model for the compensatory growth study. After a 3-weeks fasting, recovered for 3 days, 10 days and 15 days were chose as the initial, middle and late sampling sites for compensatory growth analysis, and liver samples of each time point were chose for the microarray analysis.At the same time, zebrafish fed ad libitum, as well as fasting for 3 weeks were also added to the microarray research.

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL14664
16 Samples

Download data: TXT

Series

Accession:: GSE112272

ID:: 200112272

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001886111.

Mercury-Induced Hepatotoxicity in Zebrafish

(Submitter supplied) Full title: Mercury-Induced Hepatotoxicity in Zebrafish: In Vivo Mechanistic Insights from Transcriptome Analysis, Phenotype Anchoring and Targeted Gene Expression Validation In this study, we performed microarray-based expression profiling on liver of zebrafish exposed to 200 µg/L of mercuric chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in mercury-induced adaptive responses under in vivo environment.

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL2715
24 Samples

Download data: TXT

Series

Accession:: GSE18861

ID:: 200018861

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Select item 20001110712.

Effect of starvation on the transcriptomes of the brain and liver in adult female zebrafish (Danio rerio)

(Submitter supplied) We used microarray analyses in adult female zebrafish (Danio rerio) to identify metabolic pathways regulated by starvation in two key organs that 1) serve biosynthetic and energy mobilizing functions (liver) and 2) consume energy and direct behavioral responses (brain). Starvation affected the expression of 574 transcripts in the liver, indicating an overall decrease in metabolic activity, reduced lipid metabolism, protein biosynthesis and proteolysis, and cellular respiration, and increased gluconeogenesis. more...

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL1319
18 Samples

Download data: CEL

Series

Accession:: GSE11107

ID:: 200011107

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Select item 20003872913.

Brain transcriptome variation among behaviorally distinct strains of zebrafish (Danio rerio)

(Submitter supplied) Domesticated animal populations often show profound reductions in predator avoidance and fear-related behavior compared to wild populations. These reductions are remarkably consistent and have been observed in a diverse array of taxa including fish, birds, and mammals. Experiments conducted in common environments indicate that these behavioral differences have a genetic basis. In this study, we quantified differences in fear-related behavior between wild and domesticated zebrafish strains and used microarray analysis to identify genes that may be associated with this variation. more...

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL1319
16 Samples

Download data: CEL

Series

Accession:: GSE38729

ID:: 200038729

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Select item 20015812414.

Transcriptomic Analysis of Nonylphenol Effect on Saccharomyces cerevisiae

(Submitter supplied) Nonylphenol (NP), is a bioaccumulative environmental estrogen that is widely used as a nonionic surfactant. We have previously examined short-term effects of NP on yeast cells using microarray technology. In the present study, we investigated the long-term impacts of NP on Saccharomyces cerevisiae BY4742 cells by analyzing genome-wide transcriptional profiles using RNA-sequencing. We used 2 mg/L NP concentration exposure for 40 days. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing

Platform:: GPL25927
6 Samples

Download data: XLSX

Series

Accession:: GSE158124

ID:: 200158124

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20010323215.

Deep sequencing of endogenous mRNA from Homo sapiens from four age categories in blood

(Submitter supplied) Comparison of temporal gene expression profiles to identify genes/pathways changing during ageing. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)