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Links from GEO DataSets

Items: 6

1.

ATAC-seq and RNA-seq for MDCKII 3D and 2D epithelial morphogenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Canis lupus familiaris
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21400 GPL20988
36 Samples
Download data: BW, TXT
Series
Accession:
GSE129824
ID:
200129824
2.

RNA-seq for MDCKII 3D and 2D epithelial morphogenesis.

(Submitter supplied) We performed time-course RNA-seq experiments for MDCKII 3D cell culture, and included seeding day0 cells and over-confluent 2D cells. To study how intracellular trafficking affects transcriptome changes, we also profiled trancriptome of DENND5A and AVL9 KD MDCKII cells by RNA-seq.
Organism:
Canis lupus familiaris
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21400 GPL20988
29 Samples
Download data: TXT
Series
Accession:
GSE129823
ID:
200129823
3.

ATAC-seq for MDCKII 3D and 2D epithelial morphogenesis

(Submitter supplied) We performed ATAC-seq experiments for MDCKII 3D cells, confluent 2D cells as well as seeding day0 cells to study if transcriptome changes during epithelial morphogenesis is associated with chromatin changes.
Organism:
Canis lupus familiaris
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21400
7 Samples
Download data: BW
Series
Accession:
GSE129822
ID:
200129822
4.

HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis

(Submitter supplied) Kidney development depends critically on proper ureteric bud branching giving rise to the entire collecting duct system. The transcription factor HNF1B is required for the early steps of ureteric bud branching. Yet, the molecular and cellular events regulated by HNF1B are poorly understood. We report that specific removal of Hnf1b from the ureteric bud leads to defective cell-cell contacts and apico-basal polarity during the early branching events. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18635
4 Samples
Download data: TXT
Series
Accession:
GSE106085
ID:
200106085
5.

Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin

(Submitter supplied) Skin and its appendages such as hair follicle and sweat gland are formed by Keratin-5 expressing (Krt5+) epidermal cells that are specified from primitive, Keratin-8 expressing (Krt8+) ectodermal progenitors shortly after gastrulation. Here we show that transcription factor ∆Np63 is required for converting Krt8+ ectodermal progenitors to Krt5+ epidermal progenitors and priming the underlying dermal cells to form dermal condensate by activating the Wnt/ß-Catenin pathway. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
8 Samples
Download data: MTX, TSV
Series
Accession:
GSE102086
ID:
200102086
6.

Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin

(Submitter supplied) Skin and its appendages such as hair follicle and sweat gland are formed by Keratin-5 expressing (Krt5+) epidermal cells that are specified from primitive, Keratin-8 expressing (Krt8+) ectodermal progenitors shortly after gastrulation. Here we show that transcription factor ∆Np63 is required for converting Krt8+ ectodermal progenitors to Krt5+ epidermal progenitors and priming the underlying dermal cells to form dermal condensate by activating the Wnt/ß-Catenin pathway. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13112 GPL17021
20 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE97213
ID:
200097213
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Supplemental Content

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