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Links from GEO DataSets

Items: 20

1.

microRNA expression profiling of paired primary and lymph node metastatic breast cancer patients, and gene expression profiling of MDA-MB-231 cells transfected with hsa-miR-205-5p and hsa-miR-214-3p compared to scrambled miRNA precursors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array; Expression profiling by array
Platforms:
GPL17077 GPL21576
30 Samples
Download data: TXT
Series
Accession:
GSE148848
ID:
200148848
2.

Gene expression profiling of MDA-MB-231 cells transfected with hsa-miR-205-5p and hsa-miR-214-3p compared to scrambled miRNA precursors

(Submitter supplied) We have employed whole genome microarray to identify changes in gene expression in MDA-MB-231 cells transfected with hsa-miR-205-5p and hsa-miR-214-3p compared to scrambled miRNA precursors at 72 hours after transfection.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17077
6 Samples
Download data: TXT
Series
Accession:
GSE148847
ID:
200148847
3.

microRNA expression profiling of paired primary and lymph node metastatic breast cancer patients

(Submitter supplied) Extracted total RNA from FFPE tissue were used for RNA labeling and hybridization on to the Agilent Human SurePrint 8 × 60k v16 miRNA microarray chip according to the manufacturer's protocol.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL21576
24 Samples
Download data: TXT
Series
Accession:
GSE148846
ID:
200148846
4.

New global miRSeq analysis of “miRNome”: the example of PTC and nodal metastases

(Submitter supplied) The set of expressed microRNAs in a given cell type, or “miRNome”, can be explored under many different aspects. Many studies report modulations of the miRNome in a wide variety of cancers. Papillary thyroid cancer is the most prevalent type of endocrine cancer. The presence of nodal metastases increases the risk of recurrence and mortality. In our study, we performed microRNA deep sequencing (miRSeq) of 3 PTC, their matching normal tissues and nodal metastases and designed a new bioinformatic framework to analyze variations of the different aspects of the miRNome: expression profile, isomiRs and non-templated additions distributions, mutation or A-to-I RNA-editing. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL11154
9 Samples
Download data: FA, TXT
5.

miRNA sequencing analysis of miRNAs expression in peripheral blood from pediatric patients with β-thalassemia

(Submitter supplied) To explore the relationship between miRNAs expression and pediatric patients with β-thalassemia, we analyzed abnormal expressed miRNAs in peripheral blood of pediatric β-thalassemia by miRNA sequencing.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL18573
10 Samples
Download data: XLSX
Series
Accession:
GSE241765
ID:
200241765
6.

Differentially expressed genes after miRNA or siRNA transfection in human cancer cell lines II

(Submitter supplied) To identify differentially expressed genes by anti cancer treatments (microRNAs or siRNAs) in human cancer, several cell lines (pancreatic cancer, esophageal cancer, bladder cancer, prostate cancer, renal cell carcinoma and lung squamous cell carcinoma) were subjected to Agilent whole genome microarrays.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL20844
32 Samples
Download data: TXT, XLSX
Series
Accession:
GSE77790
ID:
200077790
7.

Differentially expressed genes after miRNA or siRNA transfection in human cancer cell lines (II)

(Submitter supplied) To identify differentially expressed genes by anti cancer treatments (microRNAs or siRNAs) in human cancer, several cell lines (bladder cancer, prostate cancer, renal cell carcinoma, oral squamous cell carcinoma and lung squamous cell carcinoma) were subjected to Agilent whole genome microarrays.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL16699
32 Samples
Download data: TXT
Series
Accession:
GSE66498
ID:
200066498
8.

microRNA expression profile in retina and choroid in oxygen-induced retinopathy model

(Submitter supplied) Using Next Generation Sequencing (NGS) we profiled miRNA expression in the retina and choroid during degenerative and NV phases of oxygen-induced retinopathy (OIR).
Organism:
Rattus norvegicus
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL20084
12 Samples
Download data: XLSX
Series
Accession:
GSE129995
ID:
200129995
9.

miRNA profile of single hormone receptor positive breast cancer patients

(Submitter supplied) In the current pilot study we aimed to identify differentially expressed miRNAs in two types of single hormone receptor-positive breast cancer [ER(+)/PgR(-) and ER(-)/PgR(+)] with further distinction into HER2-overexpressing/amplified and HER2-negative tumors in a well-established cohort collected at Medical University of Gdańsk.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL28943
32 Samples
Download data: RCC
Series
Accession:
GSE155362
ID:
200155362
10.

Gene expression analysis of THP-1 cells (monocytic cell line) transfected with microRNA mimics: let-7d-3p, let-7e-5p,miR-146a-5p,miR-130a-3p, miR-151a-3p.

(Submitter supplied) In our previous study, hsa-let-7d-3p, hsa-let-7e-5p,hsa-miR-146a-5p,hsa-miR-130a-3p, hsa-miR-151a-3p,were significantly upregulated in the plasma of atopic patients. To study the each function of let-7d-3p, let-7e-5p,miR-146a-5p,miR-130a-3p, miR-151a-3p which are significantly upregulated in the plasma of atopic patients, we performed mimic-transfected THP-1 cells, a mononuclear cell line, and performed comprehensive genetic analysis.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL23159
6 Samples
Download data: CEL
Series
Accession:
GSE217971
ID:
200217971
11.

Gene expression analysis of THP-1 cells (monocytic cell line) transfected with microRNA mimics: let-7d-5p, miR-27b-3p, miR-151a-5p.

(Submitter supplied) In our previous study, hsa-let-7d-5p,hsa-miR-27b-3p,hsa-miR-151-5p were significantly upregulated in the plasma of atopic patients. To study the each function of hsa-let-7d-5p,hsa-miR-27b-3p,hsa-miR-151-5p, which are significantly upregulated in the plasma of atopic patients, we performed mimic-transfected THP-1 cells, a mononuclear cell line, and performed comprehensive genetic analysis.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL23159
4 Samples
Download data: CEL
Series
Accession:
GSE217969
ID:
200217969
12.

comprehensive miRNA analysis of human atopic plasma

(Submitter supplied) miRNAs are kown to be deeply involved in the progression of chronic inflammatory diseases. We comprehensively analyzed miRNAs in human plasma from AD(atopic dermatitis) and ACD(allergic conjunctival disease) patients. We performed a comprehensive human plasma miRNA analysis and identified significantly up-regulated miRNAs in both AD (atopic dermatitis) and ACD (allergic conjunctival disease).
Organism:
Homo sapiens; synthetic construct
Type:
Non-coding RNA profiling by array
Platform:
GPL21572
9 Samples
Download data: CEL, XLSX
Series
Accession:
GSE217232
ID:
200217232
13.

Global gene expression analysis of THP-1 cells (a monocytic cell line) transfected with hsa-let-7a-5p mimics.

(Submitter supplied) In our previous study, HAS-Let-7A-5P was significantly upregulated in the plasma of atopic patients. To study the function of hsa-let-7a-5p, which is significantly upregulated in the plasma of atopic patients, we performed mimic-transfected THP-1 cells, a mononuclear cell line, and performed comprehensive genetic analysis.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL23159
2 Samples
Download data: CEL, XLSX
Series
Accession:
GSE217224
ID:
200217224
14.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
synthetic construct; Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL14613
30 Samples
Download data: CEL
Series
Accession:
GSE183227
ID:
200183227
15.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before Transplantation and Unpaired Bone Marrow Donors

(Submitter supplied) Fanconi anemia (FA) is a rare genetic disorder characterized by genomic instability, developmental defects and bone marrow failure. Homeostasis of hematopoietic stem cells (HSCs) in the bone marrow partly relies on their direct or indirect interactions with the mesenchymal stem/stromal cells (MSCs). miRNAs can play a critical role during these interactions. There is no study available so far addressing the miRNA profile of bone marrow (BM-) MSCs in the FA disease state. more...
Organism:
Homo sapiens; synthetic construct
Type:
Non-coding RNA profiling by array
Platform:
GPL14613
9 Samples
Download data: CEL
Series
Accession:
GSE183226
ID:
200183226
16.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before and After Bone Marrow Transplantation, and their Allogeneic Bone Marrow Donors

(Submitter supplied) Fanconi anemia (FA) is a rare genetic disorder characterized by genomic instability, developmental defects and bone marrow failure. Homeostasis of hematopoietic stem cells (HSCs) in the bone marrow partly relies on their direct or indirect interactions with the mesenchymal stem/stromal cells (MSCs). miRNAs can play a critical role during these interactions. There is no study available so far addressing the miRNA profile of bone marrow (BM-) MSCs in FA disease state. more...
Organism:
synthetic construct; Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL14613
9 Samples
Download data: CEL
Series
Accession:
GSE183225
ID:
200183225
17.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before Transplantation and their Allogeneic Bone Marrow Donors

(Submitter supplied) Fanconi anemia (FA) is a rare genetic disorder characterized by genomic instability, developmental defects and bone marrow failure. Homeostasis of hematopoietic stem cells (HSCs) in the bone marrow partly relies on their direct or indirect interactions with the mesenchymal stem/stromal cells (MSCs). miRNAs can play a critical role during these interactions. There is no study available so far addressing the miRNA profile of bone marrow (BM-) MSCs in the FA disease state. more...
Organism:
Homo sapiens; synthetic construct
Type:
Non-coding RNA profiling by array
Platform:
GPL14613
12 Samples
Download data: CEL
Series
Accession:
GSE183224
ID:
200183224
18.

Tannerella forsythia intraoral infection and periodontitis in C57BL/6J mice

(Submitter supplied) Individual miRNA analyzed were successfully constructed through nanostring technology of a total of 577 mouse miRNAs in 20 number of SHAM mice and 20 number of Tannerella forsythia infected mice, which have been euthanized on the end of 16 weeks infection study.
Organism:
Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL23053
40 Samples
Download data: RCC, TXT
Series
Accession:
GSE239421
ID:
200239421
19.

EV-miRNAs as biomarkers of breast cancer recurrence

(Submitter supplied) To evaluate the miRNAs expression related to breast cancer recurrence
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL33556
23 Samples
Download data: RCC
Series
Accession:
GSE236845
ID:
200236845
20.

Microarray profiling identifies extracellular circulating miRNAs dysregulated in cystic fibrosis

(Submitter supplied) Extracellular circulating miRNAs (ECmiRNAs) play a crucial role in cell-to-cell communication and serve as non-invasive biomarkers in a wide range of diseases, but their abundance and functional relevance in cystic fibrosis (CF) remain poorly understood. Microarray technology was employed to identify aberrantly expressed plasma ECmiRNAs in CF and elucidate the functional relevance of their targets.
Organism:
Homo sapiens; synthetic construct
Type:
Non-coding RNA profiling by array
Platform:
GPL19117
10 Samples
Download data: CEL, TXT
Series
Accession:
GSE135119
ID:
200135119
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