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Links from GEO DataSets

Items: 10

1.

Single-cell RNA-Sequencing maps the hematopoietic landscape in naked mole-rats [Xeno]

(Submitter supplied) Naked mole-rats are a mammalian model organism of exceptional longevity. We mapped the hematopoietic hierarchy and used functional characterizations to define a purified stem and progenitor cell (HSPC) compartment similar to mouse LIN-/Sca-1+/Kit+ HSPCs or human LIN-/CD34+/CD38lo HSPCs.
Organism:
Heterocephalus glaber
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30845
8 Samples
Download data: RDATA
Series
Accession:
GSE185722
ID:
200185722
2.

Single-cell RNA-Sequencing maps the hematopoietic landscape in naked mole-rats [unfractionated PB]

(Submitter supplied) Naked mole-rats are a mammalian model organism of exceptional longevity. We mapped the hematopoietic hierarchy and used functional characterizations to define a purified stem and progenitor cell (HSPC) compartment similar to mouse LIN-/Sca-1+/Kit+ HSPCs or human LIN-/CD34+/CD38lo HSPCs.
Organism:
Heterocephalus glaber
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30845
7 Samples
Download data: RDATA
Series
Accession:
GSE202903
ID:
200202903
3.

Single-cell RNA-Sequencing maps the hematopoietic landscape in naked mole-rats.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Heterocephalus glaber; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL30845
42 Samples
Download data
Series
Accession:
GSE185724
ID:
200185724
4.

Single-cell RNA-Sequencing maps the hematopoietic landscape in naked mole-rats [sorted_BM_PB_THY]

(Submitter supplied) Naked mole-rats are a mammalian model organism of exceptional longevity. We mapped the hematopoietic hierarchy and used functional characterizations to define a purified stem and progenitor cell (HSPC) compartment similar to mouse LIN-/Sca-1+/Kit+ HSPCs or human LIN-/CD34+/CD38lo HSPCs.
Organism:
Heterocephalus glaber
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30845
5 Samples
Download data: RDATA
Series
Accession:
GSE185723
ID:
200185723
5.

Single-cell RNA-Sequencing maps the hematopoietic landscape in naked mole-rats [unfractionated LY]

(Submitter supplied) Naked mole-rats are a mammalian model organism of exceptional longevity. We mapped the T cell developmental landscape in Naked mole-rats and showed
Organism:
Mus musculus; Heterocephalus glaber
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL30845
14 Samples
Download data: RDATA
Series
Accession:
GSE185721
ID:
200185721
6.

Single-cell RNA-Sequencing maps the hematopoietic landscape in naked mole-rats [unfractionated BM]

(Submitter supplied) Naked mole-rats are a mammalian model organism of exceptional longevity. We mapped the hematopoietic hierarchy and used functional characterizations to define a purified stem and progenitor cell (HSPC) compartment similar to mouse LIN-/Sca-1+/Kit+ HSPCs or human LIN-/CD34+/CD38lo HSPCs.
Organism:
Mus musculus; Heterocephalus glaber
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL30845
8 Samples
Download data: RDATA
Series
Accession:
GSE185720
ID:
200185720
7.

Transcriptome sequencing of naked mole rat, Heterocephalus glaber

(Submitter supplied) Deep sequencing of mRNA from naked mole rat
Organism:
Heterocephalus glaber
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13793
13 Samples
Download data: BEDGRAPH
Series
Accession:
GSE30337
ID:
200030337
8.

The evolution of the naked mole-rat T cells

(Submitter supplied) The immune system consists of a network of specialized cells and processes that protect the organism from diseases and regulates tissue repair. Natural killer (NK) cells and the αβ and γδ T cells comprise the cytotoxic arm of the immune system and have evolved to detect and eradicate cells infected with pathogens and affected by malignancies, in order to prevent their spread and subsequent tissue damage. more...
Organism:
Heterocephalus glaber; Mus musculus
Type:
Expression profiling by high throughput sequencing
4 related Platforms
66 Samples
Download data: MTX, TSV
Series
Accession:
GSE214390
ID:
200214390
9.

RNA sequencing of the spleen of naked mole-rat and mouse

(Submitter supplied) Heathly naked mole-rats kept under normal housing conditions harbor either a small or enlarged spleen. The aim of the study is to compare RNAseq of naked mole-rat (NM-R) small and enlarged spleens between them and to compare them with RNAseq of mouse spleen.
Organism:
Mus musculus; Heterocephalus glaber
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21195 GPL17021
9 Samples
Download data: TXT
Series
Accession:
GSE179350
ID:
200179350
10.

RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.

(Submitter supplied) The goal was to find genes which are differentially expressed between the naked mole-rat (Heterocephalus glaber) and the wild-type mice liver tissue. The genes which are most differentially expressed may provide a clue for the remarkable differences between naked mole-rat and mouse in terms of longevity, cancer resistance and adaptation to subterranean environments.
Organism:
Mus musculus; Heterocephalus glaber
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL9185 GPL13940
2 Samples
Download data: TXT
Series
Accession:
GSE30764
ID:
200030764
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