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Links from GEO DataSets

Items: 20

1.

Methylation data from stored peripheral blood leukocytes from African American participants in the GENOA study with Infinium HumanMethylation450 BeadChip

(Submitter supplied) African-American individuals of the GENOA study
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
418 Samples
Download data: IDAT, TXT
Series
Accession:
GSE210254
ID:
200210254
2.

Methylation data from stored peripheral blood leukocytes from African American participants in the GENOA study

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platforms:
GPL21145 GPL13534
1812 Samples
Download data: IDAT
Series
Accession:
GSE210256
ID:
200210256
3.

Methylation data from stored peripheral blood leukocytes from African American participants in the GENOA study with Infinium HumanMethylationEPIC BeadChip

(Submitter supplied) African-American individuals of the GENOA study
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL21145
1394 Samples
Download data: IDAT, TXT
Series
Accession:
GSE210255
ID:
200210255
4.

Gene expression data from lymphoblastoid cell lines from African American participants in the GENOA study

(Submitter supplied) African-American individuals of the GENOA cohort
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL20932
1205 Samples
Download data: CEL
Series
Accession:
GSE138914
ID:
200138914
5.

Cell-type specific meQTL extends melanoma GWAS annotation beyond eQTL and identifies a melanocyte gene regulatory network

(Submitter supplied) To explore the roles of cell-type specific methylation QTL (meQTL) for melanoma GWAS annotation, we generated DNA methylation data from the same sample set as our previouse eQTL study including 106 primary melanocyte cultures. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 480,000 CpGs in 106 primary melanocyte cultures. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13534
106 Samples
Download data: IDAT, TXT
Series
Accession:
GSE166069
ID:
200166069
6.

Epigenome analysis of normal lung tissue samples

(Submitter supplied) Genome wide DNA methylation profiling of normal lung tissue samples. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs in nor mal lung tissue samples. Samples included 244 normal lung tissue samples from lung cancer patients.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
244 Samples
Download data: TXT
Series
Accession:
GSE52401
ID:
200052401
7.

Genome-wide gene expression profiles of primary prostate cancer

(Submitter supplied) Prognostic biomarkers are useful to screen patients with clinically localized prostate cancer (PCa) who are at high risk of metastatic progression. The tumor transcriptome can be used to evaluate the aggressiveness of PCa and predict adverse patient outcomes. Genomewide gene expression levels were measured in primary tumor samples of 503 patients in a population‐based cohort.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL14951
503 Samples
Download data: IDAT, TXT
Series
Accession:
GSE141551
ID:
200141551
8.

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

(Submitter supplied) The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in whole blood samples from 172 normal female twins. See Bell, Tsai et al. Plos Genet. 2012;8(4):e1002629.
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
172 Samples
Download data: TXT
Series
Accession:
GSE58045
ID:
200058045
9.

Healthy, adjacent normal and tumor colon cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by genome tiling array
Platforms:
GPL13534 GPL13667
486 Samples
Download data: CEL, IDAT
Series
Accession:
GSE166427
ID:
200166427
10.

Methylation data from healthy, adjacent normal and tumor colon cells

(Submitter supplied) Methylation profiles of paired normal adjacent mucosa and tumor samples from 96 individuals and 48 healthy colon mucosae, were obtained through Illumina Infinium Human Methylation 450K BeadChip. This dataset is in the context of the COLONOMICS project and to query additional information you can visit the project website www.colonomics.org.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
240 Samples
Download data: IDAT, TXT
Series
Accession:
GSE131013
ID:
200131013
11.

Gene expression data from healthy, adjacent normal and tumor colon cells

(Submitter supplied) Gene expression profiles of paired normal adjacent mucosa and tumor samples from 98 individuals and 50 healthy colon mucosae, were obtained through Affymetrix Human Genome U219 Arrays. This dataset is in the context of the COLONOMICS project and to query additional information you can visit the project website www.colonomics.org.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13667
246 Samples
Download data: CEL
Series
Accession:
GSE44076
ID:
200044076
12.

ZNF333 ChIP-seq in HCT116

(Submitter supplied) ZNF333 ChIP-seq in HCT116
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
6 Samples
Download data: BED
Series
Accession:
GSE183847
ID:
200183847
13.

A longitudinal and transancestral analysis of DNA methylation patterns and disease activity in lupus patients

(Submitter supplied) Epigenetic dysregulation is implicated in the pathogenesis of lupus. We performed a longitudinal analysis to assess changes in DNA methylation in neutrophils collected from 54 lupus patients over 4 years of follow up and across disease activity levels using 229 patient samples.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL21145
229 Samples
Download data: IDAT
Series
Accession:
GSE161476
ID:
200161476
14.

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils

(Submitter supplied) We identified genome-wide DNA methylation patterns within neutrophils and low-density granulocytes of Lupus patients and demographically matched controls
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
38 Samples
Download data: TXT
Series
Accession:
GSE65097
ID:
200065097
15.

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we collected methylation data at ~300,000 loci in lymphoblastoid cell lines (LCLs) from 64 HapMap Yoruba individuals, and genome-wide bisulfite sequence data in ten of these individuals. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array; Methylation profiling by high throughput sequencing
Platforms:
GPL13534 GPL11154
74 Samples
Download data: TXT
Series
Accession:
GSE57483
ID:
200057483
16.

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels [Bisulfite-array]

(Submitter supplied) DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we collected methylation data at ~300,000 loci in lymphoblastoid cell lines (LCLs) from 64 HapMap Yoruba individuals, and genome-wide bisulfite sequence data in ten of these individuals. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
64 Samples
Download data: TXT
Series
Accession:
GSE57481
ID:
200057481
17.

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels [Bisulfite-Seq]

(Submitter supplied) DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we collected methylation data at ~300,000 loci in lymphoblastoid cell lines (LCLs) from 64 HapMap Yoruba individuals, and genome-wide bisulfite sequence data in ten of these individuals. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL11154
10 Samples
Download data: TXT
Series
Accession:
GSE57471
ID:
200057471
18.

Abundant Quantitative Trait Loci for CpG Methylation and Expression Across Human Brain Tissues

(Submitter supplied) A fundamental challenge in the post-genome era is to understand and annotate the consequences of genetic variation, particularly within the context of human tissues. We describe a set of integrated experiments designed to investigate the effects of common genetic variability on DNA methylation, mRNA expression and microRNA (miRNA) expression in four distinct human brain regions. We show that brain tissues may be readily distinguished based on methylation status or expression profile. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array; Methylation profiling by array
Platforms:
GPL8490 GPL8178 GPL6104
1658 Samples
Download data: TXT
Series
Accession:
GSE15745
ID:
200015745
19.

Genome-wide DNA methylation and SNP genotyping of ǂKhomani San

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Methylation profiling by array; SNP genotyping by SNP array
4 related Platforms
105 Samples
Download data
Series
Accession:
GSE99091
ID:
200099091
20.

SNP genotyping of ǂKhomani San

(Submitter supplied) 48 ǂKhomani San living in the South African Kalahari were genotyped using the Illumina OmniExpress, OmniExpress Plus, and HumanHap550 arrays
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array
Platforms:
GPL18900 GPL6982 GPL20333
48 Samples
Download data: BIM, DATA, FAM, MAP, PED
Series
Accession:
GSE99090
ID:
200099090
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