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Links from GEO DataSets

Items: 20

1.

Characterizing Pneumocystis carinii centromeres with ChIP-seq (pc_210927)

(Submitter supplied) Pneumocystis is a relevant genetic system to study centromere formation in relation with host adaptation. How centromeres are formed and maintained in strongly host adapted fungal pathogens is poorly investigated. Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. more...
Organism:
Pneumocystis carinii
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL33206
8 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE232355
ID:
200232355

PubMed Full text in PMC Similar studies

2.

Regional Centromere Configuration in the Fungal Pathogens of Pneumocystis Genus

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Pneumocystis carinii; Pneumocystis murina
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
35 Samples
Download data: BED, BEDGRAPH, BROADPEAK, BW, NARROWPEAK
Series
Accession:
GSE255275
ID:
200255275

PubMed Full text in PMC Similar studies

3.

RNA-seq analysis of Pneumocystis murina in short term culture

(Submitter supplied) RNA-Seq analysis of Pneumocystis murina in culture at three time points post inoculation
Organism:
Pneumocystis murina
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34169
3 Samples
Download data: BW
Series
Accession:
GSE255235
ID:
200255235

PubMed Full text in PMC Similar studies

4.

DNA methylation analysis in Pneumocystis carinii using bisulfite sequencing

(Submitter supplied) Pneumocystis carinii bisulfite_seq
Organism:
Pneumocystis carinii
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL34166
1 Sample
Download data: BEDGRAPH
Series
Accession:
GSE255176
ID:
200255176

PubMed Full text in PMC Similar studies

5.

Characterizing Pneumocystis murina centromeres with ChIP-seq (pm_191010)

(Submitter supplied) Pneumocystis is a relevant genetic system to study centromere formation in relation with host adaptation. How centromeres are formed and maintained in strongly host adapted fungal pathogens is poorly investigated. Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. more...
Organism:
Pneumocystis murina
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL33410
3 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE232454
ID:
200232454

PubMed Full text in PMC Similar studies

6.

Characterizing Pneumocystis carinii centromeres with ChIP-seq (pm_211220)

(Submitter supplied) Pneumocystis is a relevant genetic system to study centromere formation in relation with host adaptation. How centromeres are formed and maintained in strongly host adapted fungal pathogens is poorly investigated. Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. more...
Organism:
Pneumocystis murina
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL33410
5 Samples
Download data: BROADPEAK, BW, NARROWPEAK
Series
Accession:
GSE232453
ID:
200232453

PubMed Full text in PMC Similar studies

7.

Characterizing Pneumocystis carinii centromeres with ChIP-seq (pc_210506)

(Submitter supplied) Pneumocystis is a relevant genetic system to study centromere formation in relation with host adaptation. How centromeres are formed and maintained in strongly host adapted fungal pathogens is poorly investigated. Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. more...
Organism:
Pneumocystis carinii
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL33206
4 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE232357
ID:
200232357

PubMed Full text in PMC Similar studies

8.

Characterizing Pneumocystis carinii centromeres with ChIP-seq III

(Submitter supplied) Pneumocystis is a relevant genetic system to study centromere formation in relation with host adaptation. How centromeres are formed and maintained in strongly host adapted fungal pathogens is poorly investigated. Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. more...
Organism:
Pneumocystis carinii
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL33206
3 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE232225
ID:
200232225

PubMed Full text in PMC Similar studies

9.

Characterizing Pneumocystis carinii centromeres with ChIP-seq II

(Submitter supplied) Pneumocystis is a relevant genetic system to study centromere formation in relation with host adaptation. How centromeres are formed and maintained in strongly host adapted fungal pathogens is poorly investigated. Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. more...
Organism:
Pneumocystis carinii
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL33206
4 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE230598
ID:
200230598

PubMed Full text in PMC Similar studies

10.

Characterizing Pneumocystis carinii centromeres with ChIP-seq

(Submitter supplied) Pneumocystis is a relevant genetic system to study centromere formation in relation with host adaptation. How centromeres are formed and maintained in strongly host adapted fungal pathogens is poorly investigated. Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. more...
Organism:
Pneumocystis carinii
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL33206
4 Samples
Download data: BED, NARROWPEAK
Series
Accession:
GSE226536
ID:
200226536

PubMed Full text in PMC Similar studies

11.

Fission yeasts CENPA and H3K9me Chip-seq

(Submitter supplied) Centromeres are the regions of eukaryotic chromosomes where kinetochores are assembled and direct the correct segregation of chromosomes. Active centromeres are defined by presence of nucleosomes containing CENP-A, a histone H3 variant, which alone is sufficient to direct kinetochore assembly. Once assembled at a location CENP-A chromatin and the kinetochore is maintained at that location though a positive feedback loop where kinetochore proteins recruited by CENP-A promote deposition of new CENP-A following replication. more...
Organism:
Schizosaccharomyces pombe; Schizosaccharomyces octosporus; Schizosaccharomyces japonicus; Schizosaccharomyces cryophilus
Type:
Genome binding/occupancy profiling by high throughput sequencing
6 related Platforms
26 Samples
Download data: BW
Series
Accession:
GSE112454
ID:
200112454

PubMed Full text in PMC Similar studies SRA Run Selector

12.

Factors that promote H3 chromatin integrity during transcription prevent promiscuous deposition of CENP-A(Cnp1) in fission yeast

(Submitter supplied) Specialized chromatin containing CENP-A nucleosomes instead of H3 nucleosomes is found at all centromeres. However, the mechanisms that specify the locations at which CENP-A chromatin is assembled remain elusive in organisms with regional, epigenetically regulated centromeres. It is known that normal centromeric DNA is transcribed in several systems including the fission yeast, Schizosaccharomyces pombe. more...
Organism:
Schizosaccharomyces pombe
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL7715
24 Samples
Download data: BAR, CEL
Series
Accession:
GSE66106
ID:
200066106

PubMed Full text in PMC Similar studies

13.

The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3

(Submitter supplied) Centromere is the chromosomal locus at which kinetochore is assembled to direct chromosome segregation. Histone H3 variant CENP-A epigenetically marks active centromeres; however, the mechanism by which CENP-A propagates at the centromere, replacing histone H3, remains poorly understood. Using fission yeast, we find that CENP-ACnp1 chromatin assembly at the centromere requires the Ino80 ATP-dependent chromatin remodeling complex which removes histone H3-containing nucleosomes from associated chromatin. more...
Organism:
Schizosaccharomyces pombe
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17225
98 Samples
Download data
Series
Accession:
GSE99589
ID:
200099589

PubMed Full text in PMC Similar studies SRA Run Selector

14.

The N-terminal Tail of CENP-A Confers Epigenetic Stability to Centromeres via the CENP-T Branch of the CCAN in Fission Yeast

(Submitter supplied) We employ the well-studied fission yeast centromere to investigate the function of the CENP-A (Cnp1) N-tail. We show that alteration of the N-tail did not affect Cnp1 loading at centromeres, outer kinetochore formation, or spindle checkpoint signaling, but nevertheless elevated chromosome loss. N-Tail mutants exhibited synthetic lethality with an altered centromeric DNA sequence, with rare survivors harboring chromosomal fusions in which the altered centromere was epigenetically inactivated. more...
Organism:
Schizosaccharomyces pombe
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL9854
4 Samples
Download data: BW
Series
Accession:
GSE63350
ID:
200063350

PubMed Full text in PMC Similar studies SRA Run Selector

15.

Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle (part 3)

(Submitter supplied) Centromeres are the regions of eukaryotic chromosomes where kinetochores are assembled and direct the correct segregation of chromosomes. Active centromeres are defined by presence of nucleosomes containing CENP-A, a histone H3 variant, which alone is sufficient to direct kinetochore assembly. Once assembled at a location CENP-A chromatin and the kinetochore is maintained at that location though a positive feedback loop where kinetochore proteins recruited by CENP-A promote deposition of new CENP-A following replication. more...
Organism:
Schizosaccharomyces pombe
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL23689 GPL25575
15 Samples
Download data: BW
Series
Accession:
GSE119922
ID:
200119922

PubMed Full text in PMC Similar studies SRA Run Selector

16.

Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Schizosaccharomyces pombe
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL23689 GPL25575 GPL17225
59 Samples
Download data: BW
Series
Accession:
GSE106494
ID:
200106494

PubMed Full text in PMC Similar studies

17.

Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle (part 2)

(Submitter supplied) Centromeres are the regions of eukaryotic chromosomes where kinetochores are assembled and direct the correct segregation of chromosomes. Active centromeres are defined by presence of nucleosomes containing CENP-A, a histone H3 variant, which alone is sufficient to direct kinetochore assembly. Once assembled at a location CENP-A chromatin and the kinetochore is maintained at that location though a positive feedback loop where kinetochore proteins recruited by CENP-A promote deposition of new CENP-A following replication. more...
Organism:
Schizosaccharomyces pombe
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17225
40 Samples
Download data: BW
Series
Accession:
GSE106492
ID:
200106492

PubMed Full text in PMC Similar studies SRA Run Selector

18.

Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle (part 1)

(Submitter supplied) Centromeres are the regions of eukaryotic chromosomes where kinetochores are assembled and direct the correct segregation of chromosomes. Active centromeres are defined by presence of nucleosomes containing CENP-A, a histone H3 variant, which alone is sufficient to direct kinetochore assembly. Once assembled at a location CENP-A chromatin and the kinetochore is maintained at that location though a positive feedback loop where kinetochore proteins recruited by CENP-A promote deposition of new CENP-A following replication. more...
Organism:
Schizosaccharomyces pombe
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17225
4 Samples
Download data: BW
Series
Accession:
GSE106491
ID:
200106491

PubMed Full text in PMC Similar studies SRA Run Selector

19.

Mediator promotes CENP-A incorporation at fission yeast centromeres

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Schizosaccharomyces pombe
Type:
Expression profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13988 GPL7715
5 Samples
Download data: BAR, BED, CEL, WIG
Series
Accession:
GSE35527
ID:
200035527

PubMed Full text in PMC Similar studies

20.

Mediator promotes CENP-A incorporation at fission yeast centromeres [ChIP-seq]

(Submitter supplied) At Schizosaccharomyces pombe centromeres, heterochromatin formation is required for de novo incorporation of the histone H3 variant CENP-A/Cnp1, which in turn directs kinetochore assembly and ultimately chromosome segregation during mitosis. Noncoding RNAs (ncRNAs) transcribed by RNA polymerase II (Pol II) directs heterochromatin formation via the RNAi machinery, but also through RNAiindependent RNA processing factors. more...
Organism:
Schizosaccharomyces pombe
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13988
3 Samples
Download data: BED, WIG
Series
Accession:
GSE35524
ID:
200035524

PubMed Full text in PMC Similar studies SRA Run Selector

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