U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 8

1.

Transcriptional profiles of venous and lymphatic endothelial cells from tie1 mutant zebrafish

(Submitter supplied) To investigate what kind of gene expression is regulated downstream of Tie1 signaling, we performed RNA-seq analyses on venous and lymphatic endothelial cells (ECs) between homozygous tie1 mutant embryos and their wild-type and heterozygous siblings during secondary sprouting, respectively. Our analyses indicate that Tie1 signaling controls a series of gene expression involved in lymphatic development including EC migration, proliferation, and differentiation.
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20828
4 Samples
Download data: CSV
Series
Accession:
GSE240329
ID:
200240329
2.

mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish.

(Submitter supplied) 48hpf kdrl:egfp zebrafish brains were dissociated using Liberase and pdgfr beta egfp postive cells FAC sorted into Trizol LS. RNA was extracted and amplified before sequencing. Samples were prepared in triplicate, with 6 brains used per samples.
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20828
6 Samples
Download data: CSV, TXT
Series
Accession:
GSE97649
ID:
200097649
3.

The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53-p21 signalling

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Danio rerio
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL14875 GPL18573
20 Samples
Download data
Series
Accession:
GSE180330
ID:
200180330
4.

The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53-p21 signalling [human]

(Submitter supplied) The development of a differentiated and functional vasculature requires coordinated control of cell fate specification, lineage differentiation and vascular network growth. Cellular proliferation is spatiotemporally regulated in developing vessel networks but how this is achieved and differentially controlled in specific lineages is unknown. Using a zebrafish forward genetic screen for mutants that form blood vessels but fail to form lymphatic vessels, we uncovered a mutant for the RNA helicase Ddx21. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
12 Samples
Download data: CSV
Series
Accession:
GSE179868
ID:
200179868
5.

Transcriptome profiling of endothelial cells from wild-type, hhex mutants and hhex-overexpression zebrafish embryos

(Submitter supplied) We used high throughput sequencing to identify differential expression in siblings, hhex mutants and hhex-overexpression endothelial cells at 48 hpf.
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20828
6 Samples
Download data: TXT
Series
Accession:
GSE111963
ID:
200111963
6.

PI3K-mediated crosstalk between angiopoietin and vascular endothelial growth factor C signaling pathways is required for lymphangiogenesis

(Submitter supplied) The aim of the study was to invetigate the crosstalk between VEGF-C/VEGFR3 and Ang2/Tie pathway
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL21493
10 Samples
Download data: MTX, TSV, TXT
Series
Accession:
GSE202989
ID:
200202989
7.

Specific fibroblast subpopulations and neuronal structures serve as local sources of Vegfc-processing components during lymphangiogenesis

(Submitter supplied) Proteolytical processing of the growth factor VEGFC through the concerted activity of CCBE1 and ADAMTS3 is required for lymphatic development to occur. How these factors act together in time and space, and which cell types produce these factors is not understood. Here we assess the function of Adamts3 and the related protease Adamts14 during zebrafish lymphangiogenesis and show both proteins to be able to process Vegfc. more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23274
1109 Samples
Download data: TXT
Series
Accession:
GSE146923
ID:
200146923
8.

Endothelial TIE1 restricts angiogenic sprouting to coordinate vein assembly in synergy with its homologue TIE2

(Submitter supplied) To investigate the receptor tyrosine kinase TIE1 in the regulation of vein development, we generated Tie1 knockout mouse line in which Tie1 expression is completely ablated.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23479
6 Samples
Download data: TXT
Series
Accession:
GSE229118
ID:
200229118
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=14|qty=4|blobid=MCID_6723f6b5b9e6a62f8e6c2606|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Support Center