Similar studies for GEO DataSets (Select 387) - GEO DataSets

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Items: 18

Select item 3871.

Evaluation of in vivo models of cardiac remodeling. Mice underwent transverse aortic constriction (TAC); myocardial infarction (MI) or sham operation. Left ventricle free wall and septum tissues examined 1 week later.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 3 protocol, 2 tissue sets

Platform:: GPL75
Series:: GSE415
18 Samples

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DataSet

Accession:: GDS387

ID:: 387

Select item 2000004152.

Mouse models of cardiac remodeling

(Submitter supplied) We employed the Affymetrix GeneChip technology to evaluate the patterns of expression in two different in vivo models of cardiac remodeling and in two different regions (left ventricle free wall and septum) of the heart. Mice underwent transverse aortic constriction (TAC); myocardial infarction (MI) or Sham operation and RNA from the left ventricle free wall and the septum was isolated 1 week later. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Datasets:: GDS387 GDS388
Platforms:: GPL75 GPL76
36 Samples

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Series

Accession:: GSE415

ID:: 200000415

Select item 3883.

Cardiac remodeling (Mu11K-B)

Organism:: Mus musculus

Type:: Expression profiling by array, count, 3 protocol, 2 tissue sets

Platform:: GPL76
Series:: GSE415
18 Samples

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DataSet

Accession:: GDS388

ID:: 388

Select item 2000017954.

Expression Profiling of DA, COP, and F1(COPxDA) rat left ventricles

(Submitter supplied) We used high density oligonucleotide arrays to measure the relative expression levels of ~27,000 probe sets in the left ventricles of inbred rat strains; DA (high performing), Copenhagen (COP, low performing), as well as F1(COPxDA) rats bred from these two strains whose performance was intermediate relative to both parental strains. DA and COP rats differ for both intrinsic aerobic running capacity (assessed with a treadmill exercise test to exhaustion) and intrinsic cardiac performance (as assessed by the Langendorff-Neeley working heart model). more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Datasets:: GDS778 GDS779 GDS780
Platforms:: GPL86 GPL87 GPL85
36 Samples

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Series

Accession:: GSE1795

ID:: 200001795

Select item 7805.

Aerobic running capacity: expression profiling of heart ventricles from various strains (RG-U34C)

Expression profiling of heart left ventricles from 15 week old inbred COP, DA, and COP x DA F1 offspring (low, high, and intermediate performers respectively). Results provide insight into mechanisms underlying aerobic capacity.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 3 strain sets

Platform:: GPL87
Series:: GSE1795
12 Samples

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DataSet

Accession:: GDS780

ID:: 780

Select item 7796.

Aerobic running capacity: expression profiling of heart ventricles from various strains (RG-U34B)

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 3 strain sets

Platform:: GPL86
Series:: GSE1795
12 Samples

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DataSet

Accession:: GDS779

ID:: 779

Select item 7787.

Aerobic running capacity: expression profiling of heart ventricles from various strains (RG-U34A)

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 3 strain sets

Platform:: GPL85
Series:: GSE1795
12 Samples

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DataSet

Accession:: GDS778

ID:: 778

Select item 2000036758.

Gene expression profiles during the development of compensated or decompensated hypertrophy during pressure overload

(Submitter supplied) We recently introduced a modification of the established monocrotaline (MCT) model for pulmonary hypertension (PH) and subsequent right ventricular (RV) hypertrophy, which allows for the selective induction of either a compensate or decompensated RV hypertrophic phenotype within four weeks after a single subcutaneous MCT injection. Both doses of 30 or 80 mg/kg body weight lead to an intermediate phase of compensated RV hypertrophy (day 14-19), while the former dose leads to a stable compensated phenotype (HYP) and the latter dose progresses towards decompensated ventricular hypertrophy and RV failure (CHF) around day 25-28 (Buermans et. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS1928
Platform:: GPL1397
27 Samples

Download data: IMAGENE

Series

Accession:: GSE3675

ID:: 200003675

Select item 2000016529.

Compensated and decompensated hypertrophy after monocrotaline injection

(Submitter supplied) 14 days after a single subcutaneous monocrotaline (MCT) injection we isolated the left and right ventricles from wistar rats. Factor1: Comparison between control (CON), compensated hypertrophy (HYP), and decompensated hypertrophy (CHF). Factor2: Comparison between left ventricle (LV) and right ventricle (RV). Keywords: dose response

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS742
Platform:: GPL1397
24 Samples

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Series

Accession:: GSE1652

ID:: 200001652

Select item 192810.

Compensated and decompensated right ventricular hypertrophy at onset: time course

Temporal analysis of right ventricles at the onset of compensated or decompensated right ventricular hypertrophy. Compensated and decompensated phenotypes induced by injection with 30 and 80 mg/kg monocrotaline, respectively. Results identify potential prognostic markers and therapeutic targets.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, log2 ratio, 3 disease state, 3 time sets

Platform:: GPL1397
Series:: GSE3675
27 Samples

Download data: IMAGENE

DataSet

Accession:: GDS1928

ID:: 1928

Select item 74211.

Compensated and decompensated hypertrophies induced by monocrotaline

Analysis of compensated and decompensated hypertrophies induced by monocrotaline in Wistar. Left and right heart ventricles examined 14 days after monocrotaline injection. Decompensated hypertrophy is a prelude to chronic heart failure.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, log ratio, 3 disease state, 2 tissue sets

Platform:: GPL1397
Series:: GSE1652
24 Samples

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DataSet

Accession:: GDS742

ID:: 742

Select item 20003640712.

mRNA Expression data from transverse aortic constriction hearts (cardiovascular disease) and sham hearts in mice.

(Submitter supplied) We used transverse aortic constraction pressure overload hypertrophy mouse hearts as a model of cardiovascular disease to study the genetic changes between TAC and SHAM (normal) mouse hearts and over 1 circadian cycle (24h). This is one approach to identify diurnal genetic biomarkers of cardiovascular disease. The micorarray approach allowed to see the gene expression in all genes in cardiovascular disease and sham hearts.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL339
36 Samples

Download data: CEL, CHP

Series

Accession:: GSE36407

ID:: 200036407

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000077513.

Mouse model of myocardial infarction

(Submitter supplied) This dataset is a time series (1 hour [h], 4 hours, 24 hours, 48 hours, 1 week [w], and 8 weeks) intended to compare normal functioning left ventricles [lv + lv2] with infarcted [ilv] and non-infarcted left ventricles [nilv]. Ilv samples are taken from the region between the LAD artery and the apex on a mouse with myocardial infarction. Lv2 samples are from the same region in a sham operated mouse. Nilv samples are taken from the region above the infartion and the left ventricle [lv] samples mimic that region in a sham mouse. The lv and lv2 samples can be compared as both are from normal functioning hearts. For more information visit http://cardiogenomics.med.harvard.edu/groups/proj1/pages/mi_home.html Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS488
Platform:: GPL81
59 Samples

Download data: CEL

Series

Accession:: GSE775

ID:: 200000775

Select item 48814.

Myocardial infarction time course

Temporal analysis of acute myocardial infarction (AMI) induced by left coronary artery ligation. Left ventricle above and below left anterior descending (LAD) artery examined at 1 hour to 8 week time points.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 disease state, 6 time, 2 tissue sets

Platform:: GPL81
Series:: GSE775
59 Samples

Download data: CEL

DataSet

Accession:: GDS488

ID:: 488

Select item 20000162115.

Differential expression of genes after 48 hrs, 10 d, and 3 wks of TAC

(Submitter supplied) Microarray analysis of gene expression after transverse aortic constriction in mice: comparison of TAC vs. sham group at 48 hours, 10 days, and 3 weeks. Keywords: time-course

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS794
Platform:: GPL81
26 Samples

Download data: CEL, EXP

Series

Accession:: GSE1621

ID:: 200001621

Select item 79416.

Cardiac hypertrophy progression: time course

Expression profiling of hearts from FVB males subjected to cardiac pressure overload by transverse aortic constriction (TAC). TAC performed on 3 month old males. Hearts examined 2, 10, and 21 days after surgery. Results provide insight into the progression of cardiac hypertrophy.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 protocol, 3 time sets

Platform:: GPL81
Series:: GSE1621
26 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS794

ID:: 794

Select item 20000245917.

Pressure overload cardiac hypertrophy

(Submitter supplied) Expression profiling of hearts from FVB males subjected to cardiac pressure overload by transverse aortic constriction (TAC). TAC performed on 8-10 weeks month old males and females. Hearts examined 30 weeks after surgery. Keywords: ordered

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2258
Platform:: GPL81
15 Samples

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Series

Accession:: GSE2459

ID:: 200002459

Select item 225818.

Cardiac left ventricular hypertrophy model

Analysis of heart left ventricles (LVs) of animals with pressure overload LV hypertrophy (LVH) caused by transverse aortic constriction. Pressure overload on the heart resulting from chronic hypertension or aortic stenosis is a stimulus for LVH. Results provide insight into the pathogenesis of LVH.