Similar studies for GEO DataSets (Select 3951) - GEO DataSets

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Items: 20

Select item 39511.

Analysis of lung tissue from patients with different types of interstitial lung disease (ILD). The ILDs represent a broad category of restrictive lung disorders. These results, together with miRNA profiling results, provide insight into molecular mechanisms underlying ILDs.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 disease state, 7 other, 4 specimen sets

Platform:: GPL570
Series:: GSE21411
29 Samples

Download data: CEL

DataSet

Accession:: GDS3951

ID:: 3951

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000214112.

Systems biology of interstitial lung diseases

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Dataset:: GDS3951
Platforms:: GPL570 GPL8936
54 Samples

Download data: CEL, TXT

Series

Accession:: GSE21411

ID:: 200021411

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000213943.

MicroRNA expression profiles of interstitial lung disease (ILD) patients

(Submitter supplied) The mechanisms and molecular pathways underlying interstitial lung diseases (ILDs) are poorly understood. Systems biology approaches were used to identify perturbed networks in these disease states to gain a better understanding of the underlying mechanisms of disease. Through profiling genes and miRNAs, we found subsets of genes and miRNAs that distinguish different disease stages, ILDs from controls, and idiopathic pulmonary fibrosis (IPF) from non-specific interstitial pneumonitis (NSIP). more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL8936
25 Samples

Download data: TXT

Series

Accession:: GSE21394

ID:: 200021394

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000213694.

Gene expression profiles of interstitial lung disease (ILD) patients

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
29 Samples

Download data: CEL

Series

Accession:: GSE21369

ID:: 200021369

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000861865.

miRNA expression data before and after TGF-β treatment and Ago2-associated transcripts in lung fibroblasts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Other; Non-coding RNA profiling by array

Platforms:: GPL21185 GPL8786
34 Samples

Download data: CEL

Series

Accession:: GSE86186

ID:: 200086186

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000861856.

miRNA expression data in unstimulated and TGF-β1-stimulated lung fibroblasts

(Submitter supplied) Lung fibroblasts play an important role in extracellular matrix homeostasis and this process is mainly regulated by transforming growth factor-beta (TGF-β). Hence, lung fibroblasts are postulated to play a crucial role in aberrant lung tissue repair and remodeling, which is a main factor in lung diseases like COPD. In this study, the effect of TGF-β1 on the miRNA expression in parenchymal lung fibroblasts is investigated.

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL8786
18 Samples

Download data: CEL

Series

Accession:: GSE86185

ID:: 200086185

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000861837.

mRNA expression profiling after Ago2-immunoprecipitation (IP) in unstimulated and TGF-β1-stimulated primary parenchymal lung fibroblasts of two control subjects

(Submitter supplied) To identify the target gene repertoire of miRNAs (i.e. the miRNA-targetome) of unstimulated and TGF-β1-stimulated primary parenchymal lung fibroblasts, Ago2-IP was performed followed by mRNA expression profiling.

Organism:: Homo sapiens

Type:: Other

Platform:: GPL21185
16 Samples

Download data: TXT

Series

Accession:: GSE86183

ID:: 200086183

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000812948.

Lung gene expression

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL18991 GPL16384
40 Samples

Download data: CEL

Series

Accession:: GSE81294

ID:: 200081294

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000812939.

Expression of miRNA from lung tissue from Systemic Sclerosis patients with interstitial lung disease (SSc-ILD) and healthy controls.

(Submitter supplied) Objective: MicroRNAs (miRNAs) control key elements of mRNA stability and likely contribute to the dysregulated lung gene expression observed in systemic sclerosis associated interstitial lung disease (SSc-ILD). We analyzed the miRNA gene expression of tissue and cells from SSc-ILD patients. A chronic lung fibrotic murine model was used. Methods: RNA was isolated from lung tissue of 12 SSc-ILD patients and 5 control lungs. more...

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL16384
20 Samples

Download data: CEL, XLSX

Series

Accession:: GSE81293

ID:: 200081293

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Select item 20008129210.

Expression of mRNA from lung tissue from Systemic Sclerosis patients with interstitial lung disease (SSc-ILD) and healthy controls (HC)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL18991
20 Samples

Download data: CEL, XLSX

Series

Accession:: GSE81292

ID:: 200081292

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20003897411.

Gene expression networks in COPD: microRNA and mRNA regulation

(Submitter supplied) 70 miRNAs and 2667 mRNAs were differentially expressed between lung tissue from subjects with COPD and smokers without COPD. miRNA and mRNA expression profiles enriched for biological pathways that may be relevant to the pathogenesis of COPD including the transforming growth factor b, Wnt and focal adhesion pathways. miR-223 and miR-1274a were the most affected miRNAs in subjects with COPD compared with smokers without obstruction. more...

Organism:: Mus musculus; Human gammaherpesvirus 8; Rattus norvegicus; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Homo sapiens; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Human alphaherpesvirus 1; human gammaherpesvirus 4; Betapolyomavirus macacae

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL4133 GPL7723
59 Samples

Download data

Series

Accession:: GSE38974

ID:: 200038974

Select item 20014630612.

A Network of Sputum MicroRNAs is Associated with Neutrophilic Airway Inflammation in Asthma

(Submitter supplied) Background: MicroRNAs are potent regulators of biologic systems that are critical to tissue homeostasis. Individual microRNAs have been identified in airway samples. However, a systems analysis of the microRNA-mRNA networks present in the sputum that contribute to airway inflammation in asthma has not been published. Methods: We conducted a genome-wide analysis of microRNA and messenger RNA (mRNA) in the sputum from patients with asthma and correlated expression with clinical phenotypes. more...

Organism:: Homo sapiens

Type:: Other

Platform:: GPL26945
89 Samples

Download data: RCC

Series

Accession:: GSE146306

ID:: 200146306

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Select item 20005822013.

Expression data from primary term human decidual cells treated with interleukin-1-beta for 6 hours.

(Submitter supplied) Preterm birth is an important unsolved clinical problem. Despite advanced treatments, infants who survive prematurity remain at increased risk for permanent disabilities. In approximately one-third of cases, prematurity is related to infection and/or inflammation, which renders hostile the normally receptive intrauterine environment. Proinflammatory cytokines provoke up-regulation of genes that promote uterine contractions. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16686
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE58220

ID:: 200058220

Select item 20006759714.

Identifying microRNAs targeting WNT/β-catenin pathway in end-stage idiopathic pulmonary arterial hypertension

(Submitter supplied) Whole genome microRNA microarray expression profiling was employed as a discovery platform to identify microRNAs dysregulated in end-stage idiopathic pulmonary arterial hypertension (IPAH) patients. Lung tissue from seven IPAH patients and eight failed donor controls were subjected to microarray screening. Twenty-one miRNAs were identified dyeregulated in IPAH patients compared to controls. In miRNA real-time PCR validation, 22 IPAH patients and 22 control subjects were enrolled, including the 7 IPAH and 8 controls in microarray screening. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL18402
15 Samples

Download data: TXT

Series

Accession:: GSE67597

ID:: 200067597

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Select item 20006958015.

Differential miRNA expression profiles betweenHBV-related HCC tumor versus non-tumor liver tissue

(Submitter supplied) miRNA played an important role in the process of carcinogenesis in HBV related hepatocellular carcinoma. Therefore, we performed miRNA microarray to evaluate the miRNAs that expressed differentially between HCC tumor versus non-tumor liver tissues.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL10850
10 Samples

Download data: TXT

Series

Accession:: GSE69580

ID:: 200069580

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Select item 20001538716.

microRNA and mRNA expression in human hepatitis C Virus

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL887 GPL6955
153 Samples

Download data: TXT

Series

Accession:: GSE15387

ID:: 200015387

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001533117.

mRNA expression in human hepatitis c virus (HCV) liver biopsy samples

(Submitter supplied) In order to infer the inverse expression relationships between microRNAs and mRNAs during HCV infection, we profiled both microRNA and mRNA expressions in HCV positive (HCV+) and HCV negative (HCV-) human liver biopsy tissue samples. This series includes all mRNA profiles.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL887
117 Samples

Download data: TXT

Series

Accession:: GSE15331

ID:: 200015331

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001528818.

microRNA expression in human hepatitis c virus (HCV) liver biopsy samples

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
36 Samples

Download data: TXT

Series

Accession:: GSE15288

ID:: 200015288

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008318919.

PyMT 4 stages tumor progression microRNA sequencing

(Submitter supplied) We sequenced mammary gland samples of MMTV-PyMT mouse from 4 stages (hyperplasia at week 6, adenoma/MIN at week 8, early carcinoma at week 10, and late carcinoma with lung metastasis at week 12) during tumor progression.