|
| Status |
Public on Dec 08, 2011 |
| Title |
Gene expression profile of developing adipose tissue in vivo |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Obesity is characterized by an increase in the size and the number of adipocytes. However, the mechanisms responsible for the formation of adipocytes during development and the molecular mechanisms regulating their increase and maintenance in adulthood are poorly understood. Here, we report the use of leptin-luciferase BAC transgenic mice to track white adipose tissue (WAT) development and guide the isolation and molecular characterization of adipocytes during development using DNA microarrays. These data reveal distinct transcriptional programs that are regulated during murine WAT development in vivo.
|
| |
|
| Overall design |
Developing mouse adipose tissue from at least 3 embryos were pooled for embryonic and postnatal time points.
|
| |
|
| Contributor(s) |
Birsoy K, Rodeheffer M, Friedman JM |
| Citation(s) |
21989915 |
| |
| Submission date |
May 24, 2011 |
| Last update date |
Jun 14, 2018 |
| Contact name |
kivanc birsoy |
| E-mail(s) |
kbirsoy@wi.mit.edu
|
| Organization name |
Rockefeller University
|
| Street address |
1230 Rockefeller University
|
| City |
new york |
| ZIP/Postal code |
10065 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA141385 |
Less...
More...