U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal volitional state

MedGen UID:
1053648
•Concept ID:
CN378236
•
Finding
Synonyms: Abnormal energy; Abnormal motivation
 
HPO: HP:0025780

Definition

An abnormality of internal states of motivation or drive that compromise, or interfere with, the ability of the person to attend to basic personal, social, or vocational activities. [from HPO]

Professional guidelines

PubMed

Treatment Associated Changes of Functional Connectivity of Midbrain/Brainstem Nuclei in Major Depressive Disorder.
Wagner G, de la Cruz F, Köhler S, Bär KJ
Sci Rep 2017 Aug 17;7(1):8675. doi: 10.1038/s41598-017-09077-5. PMID: 28819132Free PMC Article

Recent clinical studies

Etiology

The Association of Intra-Abdominal Adhesions with Peritoneal Dialysis Catheter-Related Complications.
Qureshi MA, Maierean S, Crabtree JH, Clarke A, Armstrong S, Fissell R, Jain AK, Jassal SV, Hu SL, Kennealey P, Liebman S, McCormick B, Momciu B, Pauly RP, Pellegrino B, Perl J, Pirkle JL Jr, Plumb TJ, Seshasai R, Shah A, Shah N, Shen J, Singh G, Tennankore K, Uribarri J, Vasilevsky M, Yang R, Quinn RR, Nadler A, Oliver MJ; North American Peritoneal Dialysis Registry
Clin J Am Soc Nephrol 2024 Apr 1;19(4):472-482. Epub 2024 Jan 8 doi: 10.2215/CJN.0000000000000404. PMID: 38190176Free PMC Article
Obesity and risk of female reproductive conditions: A Mendelian randomisation study.
Venkatesh SS, Ferreira T, Benonisdottir S, Rahmioglu N, Becker CM, Granne I, Zondervan KT, Holmes MV, Lindgren CM, Wittemans LBL
PLoS Med 2022 Feb;19(2):e1003679. Epub 2022 Feb 1 doi: 10.1371/journal.pmed.1003679. PMID: 35104295Free PMC Article
Goal-directed action planning in infants with Down syndrome.
Schworer EK, Fidler DJ, Kaur M, Needham AW, Prince MA, Daunhauer LA
J Intellect Disabil Res 2020 Sep;64(9):713-724. Epub 2020 Jul 15 doi: 10.1111/jir.12763. PMID: 32666591
Age-related changes in motor cortical properties and voluntary activation of skeletal muscle.
Clark BC, Taylor JL
Curr Aging Sci 2011 Dec;4(3):192-9. doi: 10.2174/1874609811104030192. PMID: 21529329Free PMC Article
Common neural circuitry supporting volitional saccades and its disruption in schizophrenia patients and relatives.
Camchong J, Dyckman KA, Austin BP, Clementz BA, McDowell JE
Biol Psychiatry 2008 Dec 15;64(12):1042-50. Epub 2008 Aug 9 doi: 10.1016/j.biopsych.2008.06.015. PMID: 18692173Free PMC Article

Diagnosis

Facial synkinesis: A distressing sequela of facial palsy.
Shokri T, Patel S, Ziai K, Harounian J, Lighthall JG
Ear Nose Throat J 2024 Jun;103(6):NP382-NP391. Epub 2021 Nov 26 doi: 10.1177/01455613211054627. PMID: 34836457
Obesity and risk of female reproductive conditions: A Mendelian randomisation study.
Venkatesh SS, Ferreira T, Benonisdottir S, Rahmioglu N, Becker CM, Granne I, Zondervan KT, Holmes MV, Lindgren CM, Wittemans LBL
PLoS Med 2022 Feb;19(2):e1003679. Epub 2022 Feb 1 doi: 10.1371/journal.pmed.1003679. PMID: 35104295Free PMC Article
Canadian Association of Neuroscience Review: Respiratory control and behavior in humans: lessons from imaging and experiments of nature.
Moss IR
Can J Neurol Sci 2005 Aug;32(3):287-97. doi: 10.1017/s0317167100004157. PMID: 16225168
Cognitive impairment in schizophrenia is the core of the disorder.
Elvevåg B, Goldberg TE
Crit Rev Neurobiol 2000;14(1):1-21. PMID: 11253953
The imbalanced brain: from normal behavior to schizophrenia.
Grossberg S
Biol Psychiatry 2000 Jul 15;48(2):81-98. doi: 10.1016/s0006-3223(00)00903-3. PMID: 10903405

Therapy

The Association of Intra-Abdominal Adhesions with Peritoneal Dialysis Catheter-Related Complications.
Qureshi MA, Maierean S, Crabtree JH, Clarke A, Armstrong S, Fissell R, Jain AK, Jassal SV, Hu SL, Kennealey P, Liebman S, McCormick B, Momciu B, Pauly RP, Pellegrino B, Perl J, Pirkle JL Jr, Plumb TJ, Seshasai R, Shah A, Shah N, Shen J, Singh G, Tennankore K, Uribarri J, Vasilevsky M, Yang R, Quinn RR, Nadler A, Oliver MJ; North American Peritoneal Dialysis Registry
Clin J Am Soc Nephrol 2024 Apr 1;19(4):472-482. Epub 2024 Jan 8 doi: 10.2215/CJN.0000000000000404. PMID: 38190176Free PMC Article
Facial synkinesis: A distressing sequela of facial palsy.
Shokri T, Patel S, Ziai K, Harounian J, Lighthall JG
Ear Nose Throat J 2024 Jun;103(6):NP382-NP391. Epub 2021 Nov 26 doi: 10.1177/01455613211054627. PMID: 34836457
Obesity and risk of female reproductive conditions: A Mendelian randomisation study.
Venkatesh SS, Ferreira T, Benonisdottir S, Rahmioglu N, Becker CM, Granne I, Zondervan KT, Holmes MV, Lindgren CM, Wittemans LBL
PLoS Med 2022 Feb;19(2):e1003679. Epub 2022 Feb 1 doi: 10.1371/journal.pmed.1003679. PMID: 35104295Free PMC Article
Strategies to augment volitional and reflex function may improve locomotor capacity following incomplete spinal cord injury.
Leech KA, Kim HE, Hornby TG
J Neurophysiol 2018 Mar 1;119(3):894-903. Epub 2017 Nov 1 doi: 10.1152/jn.00051.2017. PMID: 29093168Free PMC Article
Reflexive and volitional saccades: biomarkers of Huntington disease severity and progression.
Patel SS, Jankovic J, Hood AJ, Jeter CB, Sereno AB
J Neurol Sci 2012 Feb 15;313(1-2):35-41. Epub 2011 Oct 21 doi: 10.1016/j.jns.2011.09.035. PMID: 22018763Free PMC Article

Prognosis

Obesity and risk of female reproductive conditions: A Mendelian randomisation study.
Venkatesh SS, Ferreira T, Benonisdottir S, Rahmioglu N, Becker CM, Granne I, Zondervan KT, Holmes MV, Lindgren CM, Wittemans LBL
PLoS Med 2022 Feb;19(2):e1003679. Epub 2022 Feb 1 doi: 10.1371/journal.pmed.1003679. PMID: 35104295Free PMC Article
Cingulate role in Tourette syndrome.
O'Neill J, Piacentini JC, Peterson BS
Handb Clin Neurol 2019;166:165-221. doi: 10.1016/B978-0-444-64196-0.00011-X. PMID: 31731911
Reflexive and volitional saccades: biomarkers of Huntington disease severity and progression.
Patel SS, Jankovic J, Hood AJ, Jeter CB, Sereno AB
J Neurol Sci 2012 Feb 15;313(1-2):35-41. Epub 2011 Oct 21 doi: 10.1016/j.jns.2011.09.035. PMID: 22018763Free PMC Article
Cognitive impairment in schizophrenia is the core of the disorder.
Elvevåg B, Goldberg TE
Crit Rev Neurobiol 2000;14(1):1-21. PMID: 11253953
The imbalanced brain: from normal behavior to schizophrenia.
Grossberg S
Biol Psychiatry 2000 Jul 15;48(2):81-98. doi: 10.1016/s0006-3223(00)00903-3. PMID: 10903405

Clinical prediction guides

The Association of Intra-Abdominal Adhesions with Peritoneal Dialysis Catheter-Related Complications.
Qureshi MA, Maierean S, Crabtree JH, Clarke A, Armstrong S, Fissell R, Jain AK, Jassal SV, Hu SL, Kennealey P, Liebman S, McCormick B, Momciu B, Pauly RP, Pellegrino B, Perl J, Pirkle JL Jr, Plumb TJ, Seshasai R, Shah A, Shah N, Shen J, Singh G, Tennankore K, Uribarri J, Vasilevsky M, Yang R, Quinn RR, Nadler A, Oliver MJ; North American Peritoneal Dialysis Registry
Clin J Am Soc Nephrol 2024 Apr 1;19(4):472-482. Epub 2024 Jan 8 doi: 10.2215/CJN.0000000000000404. PMID: 38190176Free PMC Article
Obesity and risk of female reproductive conditions: A Mendelian randomisation study.
Venkatesh SS, Ferreira T, Benonisdottir S, Rahmioglu N, Becker CM, Granne I, Zondervan KT, Holmes MV, Lindgren CM, Wittemans LBL
PLoS Med 2022 Feb;19(2):e1003679. Epub 2022 Feb 1 doi: 10.1371/journal.pmed.1003679. PMID: 35104295Free PMC Article
Cingulate role in Tourette syndrome.
O'Neill J, Piacentini JC, Peterson BS
Handb Clin Neurol 2019;166:165-221. doi: 10.1016/B978-0-444-64196-0.00011-X. PMID: 31731911
Reflexive and volitional saccades: biomarkers of Huntington disease severity and progression.
Patel SS, Jankovic J, Hood AJ, Jeter CB, Sereno AB
J Neurol Sci 2012 Feb 15;313(1-2):35-41. Epub 2011 Oct 21 doi: 10.1016/j.jns.2011.09.035. PMID: 22018763Free PMC Article
Cognitive impairment in schizophrenia is the core of the disorder.
Elvevåg B, Goldberg TE
Crit Rev Neurobiol 2000;14(1):1-21. PMID: 11253953

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...