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Pyriform Fossa Neoplasm

MedGen UID:
138025
•Concept ID:
C0345704
•
Neoplastic Process
Synonyms: Neoplasm of Pyriform Fossa; Neoplasm of pyriform sinus; Neoplasm of Pyriform Sinus; Neoplasm of the Pyriform Fossa; Neoplasm of the Pyriform Sinus; Pyriform Fossa Tumor; Pyriform Sinus Neoplasm; Pyriform Sinus Tumor; Tumor of pyriform fossa; Tumor of Pyriform Fossa; Tumor of Pyriform Sinus; Tumor of the Pyriform Fossa; Tumor of the Pyriform Sinus
SNOMED CT: Neoplasm of pyriform sinus (126688006); Tumor of pyriform fossa (126688006)

Definition

A benign or malignant neoplasm that affects the pyriform sinus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPyriform Fossa Neoplasm

Professional guidelines

PubMed

Integrated cone-beam CT and fluoroscopic navigation in treatment of head and neck vascular malformations and tumors.
Nesbit GM, Nesbit EG, Hamilton BE
J Neurointerv Surg 2011 Jun;3(2):186-90. Epub 2010 Dec 16 doi: 10.1136/jnis.2010.003376. PMID: 21990816
Hypopharyngeal cancer: results of treatment based on radiation therapy and salvage surgery.
Godballe C, Jørgensen K, Hansen O, Bastholt L
Laryngoscope 2002 May;112(5):834-8. doi: 10.1097/00005537-200205000-00011. PMID: 12150614
Carcinoma of the pyriform sinus a comparison of treatment modalities.
Eisbach KJ, Krause CJ
Laryngoscope 1977 Nov;87(11):1904-10. doi: 10.1002/lary.1977.87.11.1904. PMID: 916786

Recent clinical studies

Etiology

Low-grade myofibroblastic sarcoma of the piriform fossa: a case report with a literature review of a tumour with a predilection for the head and neck.
Coyne JD
Br J Oral Maxillofac Surg 2007 Jun;45(4):335-7. Epub 2006 Jan 6 doi: 10.1016/j.bjoms.2005.10.015. PMID: 16406178
Third and fourth branchial pouch anomalies.
Rea PA, Hartley BE, Bailey CM
J Laryngol Otol 2004 Jan;118(1):19-24. doi: 10.1258/002221504322731574. PMID: 14979967
Cancer of the pyriform fossa: hyperfractionated radiotherapy as a primary treatment modality.
Conlon BJ, Walsh M, McShane D, Corcoran N, Moriarty M, Healy JB, Fraser I, O'Dwyer TP
Clin Otolaryngol Allied Sci 1997 Aug;22(4):327-31. doi: 10.1046/j.1365-2273.1997.00016.x. PMID: 9298607
Lymph node invasion in hypopharynx and lateral epilarynx carcinoma: a prognostic factor.
Lefebvre JL, Castelain B, De la Torre JC, Delobelle-Deroide A, Vankemmel B
Head Neck Surg 1987 Sep-Oct;10(1):14-8. doi: 10.1002/hed.2890100104. PMID: 3449476
The incidence of hypopharyngeal stenosis after surgery for laryngeal cancer.
Kaplan JN, Dobie RA, Cummings CW
Otolaryngol Head Neck Surg 1981 Nov-Dec;89(6):956-9. doi: 10.1177/019459988108900615. PMID: 6801597

Diagnosis

Nerve afflictions of maxillofacial region: a report of two cases.
Thada SR, Gadda R, Pai K
BMJ Case Rep 2013 Oct 21;2013 doi: 10.1136/bcr-2013-201002. PMID: 24145506Free PMC Article
Low-grade myofibroblastic sarcoma of the piriform fossa: a case report with a literature review of a tumour with a predilection for the head and neck.
Coyne JD
Br J Oral Maxillofac Surg 2007 Jun;45(4):335-7. Epub 2006 Jan 6 doi: 10.1016/j.bjoms.2005.10.015. PMID: 16406178
Third and fourth branchial pouch anomalies.
Rea PA, Hartley BE, Bailey CM
J Laryngol Otol 2004 Jan;118(1):19-24. doi: 10.1258/002221504322731574. PMID: 14979967
Cartilaginous tumors of the trachea and larynx.
Neis PR, McMahon MF, Norris CW
Ann Otol Rhinol Laryngol 1989 Jan;98(1 Pt 1):31-6. doi: 10.1177/000348948909800107. PMID: 2642679
Cervical metastasis from an unknown primary.
Fried MP, Diehl WH Jr, Brownson RJ, Sessions DG, Ogura JH
Ann Otol Rhinol Laryngol 1975 Mar-Apr;84(2 PART 1):152-7. doi: 10.1177/000348947508400202. PMID: 1124902

Therapy

Nerve afflictions of maxillofacial region: a report of two cases.
Thada SR, Gadda R, Pai K
BMJ Case Rep 2013 Oct 21;2013 doi: 10.1136/bcr-2013-201002. PMID: 24145506Free PMC Article
Pitfalls in the surgical management of cancer of the larynx and hypopharynx.
Thabet MH, Talaat M, Rizk AM
Otolaryngol Head Neck Surg 2000 Oct;123(4):482-7. doi: 10.1067/mhn.2000.105062. PMID: 11020190
Cancer of the pyriform fossa: hyperfractionated radiotherapy as a primary treatment modality.
Conlon BJ, Walsh M, McShane D, Corcoran N, Moriarty M, Healy JB, Fraser I, O'Dwyer TP
Clin Otolaryngol Allied Sci 1997 Aug;22(4):327-31. doi: 10.1046/j.1365-2273.1997.00016.x. PMID: 9298607
The incidence of hypopharyngeal stenosis after surgery for laryngeal cancer.
Kaplan JN, Dobie RA, Cummings CW
Otolaryngol Head Neck Surg 1981 Nov-Dec;89(6):956-9. doi: 10.1177/019459988108900615. PMID: 6801597
Osteonecrosis of hyoid bone and thyroid cartilage.
Bhatia PL, Dutta NK, Sanasam JC
Arch Otolaryngol 1979 Sep;105(9):553-4. doi: 10.1001/archotol.1979.00790210051011. PMID: 475654

Prognosis

Early detection of isolated pleural metastasis from carcinoma pyriform fossa: Can it be steered away from doom?
Vashistha B, Garg P, Negi P, Kingsley PA
J Cancer Res Ther 2022 Jan-Mar;18(1):280-281. doi: 10.4103/jcrt.JCRT_1739_20. PMID: 35381801
A giant esophageal liposarcoma radically resected by the cervical approach: a case report.
Furukawa H, Tanemura M, Matsuda H, Uotani T, Matsumoto K, Okuno J, Higashi S, Nonaka R, Tsunashima R, Wakasugi M, Miyake M, Iiboshi Y
Clin J Gastroenterol 2022 Feb;15(1):71-76. Epub 2021 Nov 7 doi: 10.1007/s12328-021-01550-z. PMID: 34743312
Pitfalls in the surgical management of cancer of the larynx and hypopharynx.
Thabet MH, Talaat M, Rizk AM
Otolaryngol Head Neck Surg 2000 Oct;123(4):482-7. doi: 10.1067/mhn.2000.105062. PMID: 11020190
Cancer of the pyriform fossa: hyperfractionated radiotherapy as a primary treatment modality.
Conlon BJ, Walsh M, McShane D, Corcoran N, Moriarty M, Healy JB, Fraser I, O'Dwyer TP
Clin Otolaryngol Allied Sci 1997 Aug;22(4):327-31. doi: 10.1046/j.1365-2273.1997.00016.x. PMID: 9298607
Supraglottic cancer.
Bocca E
Laryngoscope 1975 Aug;85(8):1318-26. doi: 10.1288/00005537-197508000-00007. PMID: 1160463

Clinical prediction guides

Swallowing in advanced oral cancers: A prospective observational study.
Malik A, Sharin F, Balaji A, Mathur Y, Nair S, Chaturvedi P, Nair D
J Cancer Res Ther 2024 Jan 1;20(1):340-348. Epub 2024 Mar 29 doi: 10.4103/jcrt.jcrt_1499_22. PMID: 38554344
Surgical approach of laryngofissure combined with epiglottis valley in treating locally-advanced pyriform sinus carcinoma.
Wu P, Tang Y, Fang X, Zhao S
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2021 Aug 28;46(8):843-850. doi: 10.11817/j.issn.1672-7347.2021.200996. PMID: 34565728Free PMC Article
Hypopharynx and larynx defect repair after resection for pyriform fossa cancer with a platysma skin flap.
Cai Q, Liang F, Huang X, Han P, Pan Y, Zheng Y
Otolaryngol Head Neck Surg 2015 Feb;152(2):374-6. Epub 2014 Nov 26 doi: 10.1177/0194599814559508. PMID: 25428776
Laryngeal carcinoma--modifications in surgical technique based on an understanding of tumor growth characteristics.
van Nostrand AW, Brodarec I
J Otolaryngol 1982 Jun;11(3):186-90. PMID: 7109016
The efficacy of combining radiation therapy with a surgical procedure in patients with cervical metastasis from squamous cancer of the oropharynx and hypopharynx.
Jesse RH, Lindberg RD
Cancer 1975 Apr;35(4):1163-6. doi: 10.1002/1097-0142(197504)35:4<1163::aid-cncr2820350422>3.0.co;2-c. PMID: 1116107

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