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Metastatic Malignant Germ Cell Tumor

MedGen UID:
1386262
•Concept ID:
C4330674
•
Neoplastic Process
Synonyms: Metastatic Germ Cell Neoplasm; Metastatic Germ Cell Tumor

Definition

A malignant germ cell tumor that has spread from its original site of growth to another anatomic site. [from NCI]

Professional guidelines

PubMed

European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics: Update 2022.
Garbe C, Amaral T, Peris K, Hauschild A, Arenberger P, Basset-Seguin N, Bastholt L, Bataille V, Del Marmol V, Dréno B, Fargnoli MC, Forsea AM, Grob JJ, Höller C, Kaufmann R, Kelleners-Smeets N, Lallas A, Lebbé C, Lytvynenko B, Malvehy J, Moreno-Ramirez D, Nathan P, Pellacani G, Saiag P, Stratigos AJ, Van Akkooi ACJ, Vieira R, Zalaudek I, Lorigan P; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO), and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2022 Jul;170:236-255. Epub 2022 May 12 doi: 10.1016/j.ejca.2022.03.008. PMID: 35570085
Current state of melanoma diagnosis and treatment.
Davis LE, Shalin SC, Tackett AJ
Cancer Biol Ther 2019;20(11):1366-1379. Epub 2019 Aug 1 doi: 10.1080/15384047.2019.1640032. PMID: 31366280Free PMC Article
Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.
Lenders JW, Duh QY, Eisenhofer G, Gimenez-Roqueplo AP, Grebe SK, Murad MH, Naruse M, Pacak K, Young WF Jr; Endocrine Society
J Clin Endocrinol Metab 2014 Jun;99(6):1915-42. doi: 10.1210/jc.2014-1498. PMID: 24893135

Recent clinical studies

Diagnosis

Long-term disease-free survival in a child with refractory metastatic malignant germ cell tumor treated by high-dose chemotherapy with autologous bone marrow rescues.
Devalck C, Tempels D, Ferster A, De Laet MH, Bujan W, Heiman P, Sariban E
Med Pediatr Oncol 1994;22(3):208-10. doi: 10.1002/mpo.2950220311. PMID: 8272012

Therapy

Long-term disease-free survival in a child with refractory metastatic malignant germ cell tumor treated by high-dose chemotherapy with autologous bone marrow rescues.
Devalck C, Tempels D, Ferster A, De Laet MH, Bujan W, Heiman P, Sariban E
Med Pediatr Oncol 1994;22(3):208-10. doi: 10.1002/mpo.2950220311. PMID: 8272012

Prognosis

False-positive serum human chorionic gonadotropin (HCG) in a male patient with a malignant germ cell tumor of the testis: a case report and review of the literature.
Ballieux BE, Weijl NI, Gelderblom H, van Pelt J, Osanto S
Oncologist 2008 Nov;13(11):1149-54. Epub 2008 Nov 4 doi: 10.1634/theoncologist.2008-0159. PMID: 18984875
Long-term disease-free survival in a child with refractory metastatic malignant germ cell tumor treated by high-dose chemotherapy with autologous bone marrow rescues.
Devalck C, Tempels D, Ferster A, De Laet MH, Bujan W, Heiman P, Sariban E
Med Pediatr Oncol 1994;22(3):208-10. doi: 10.1002/mpo.2950220311. PMID: 8272012

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