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Locally Advanced Basal Cell Carcinoma

MedGen UID:
1652163
Concept ID:
C4745056
Neoplastic Process

Definition

A basal cell carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Basal Cell Carcinoma

Professional guidelines

PubMed

Sanmartín O, Llombart B, Carretero Hernández G, Flórez Menéndez Á, Botella-Estrada R, Herrera Ceballos E, Puig S
Actas Dermosifiliogr (Engl Ed) 2021 Apr;112(4):295-301. Epub 2020 Nov 13 doi: 10.1016/j.ad.2020.11.002. PMID: 33197438
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414
Gutzmer R, Solomon JA
Target Oncol 2019 Jun;14(3):253-267. doi: 10.1007/s11523-019-00648-2. PMID: 31243642

Recent clinical studies

Etiology

Damsin T, Lebas E, Marchal N, Rorive A, Nikkels AF
Expert Rev Anticancer Ther 2022 Mar;22(3):243-248. Epub 2022 Feb 22 doi: 10.1080/14737140.2022.2043748. PMID: 35175882
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414
Burness CB, Scott LJ
Target Oncol 2016 Apr;11(2):239-46. doi: 10.1007/s11523-016-0418-9. PMID: 26867946
Amici JM, Battistella M, Beylot-Barry M, Chatellier A, Dalac-Ra S, Dreno B, Falandry C, Froget N, Giacchero D, Grob JJ, Guerreschir P, Leccia MT, Malard O, Mortier L, Routier E, Stefan A, Stefan D, Stoebner PE, Basset-Seguin N
Eur J Dermatol 2015 Nov-Dec;25(6):586-94. doi: 10.1684/ejd.2015.2641. PMID: 26574792

Diagnosis

Mesti T, Sever M, Ocvirk J
Dermatology 2023;239(1):158-164. Epub 2022 Jul 27 doi: 10.1159/000525612. PMID: 35896082Free PMC Article
Gupta N, Ruiz ES
Drug Des Devel Ther 2022;16:183-190. Epub 2022 Jan 14 doi: 10.2147/DDDT.S325852. PMID: 35058688Free PMC Article
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Campione E, Di Prete M, Lozzi F, Lanna C, Spallone G, Mazzeo M, Cosio T, Rapanotti C, Dika E, Gaziano R, Orlandi A, Bianchi L
Chemotherapy 2020;65(1-2):2-10. Epub 2020 Aug 10 doi: 10.1159/000509156. PMID: 32777789
Gutzmer R, Solomon JA
Target Oncol 2019 Jun;14(3):253-267. doi: 10.1007/s11523-019-00648-2. PMID: 31243642

Therapy

Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Sanmartín O, Llombart B, Carretero Hernández G, Flórez Menéndez Á, Botella-Estrada R, Herrera Ceballos E, Puig S
Actas Dermosifiliogr (Engl Ed) 2021 Apr;112(4):295-301. Epub 2020 Nov 13 doi: 10.1016/j.ad.2020.11.002. PMID: 33197438
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414
Burness CB, Scott LJ
Target Oncol 2016 Apr;11(2):239-46. doi: 10.1007/s11523-016-0418-9. PMID: 26867946
Sekulic A, Migden MR, Oro AE, Dirix L, Lewis KD, Hainsworth JD, Solomon JA, Yoo S, Arron ST, Friedlander PA, Marmur E, Rudin CM, Chang AL, Low JA, Mackey HM, Yauch RL, Graham RA, Reddy JC, Hauschild A
N Engl J Med 2012 Jun 7;366(23):2171-9. doi: 10.1056/NEJMoa1113713. PMID: 22670903Free PMC Article

Prognosis

Véron M, Chevret S, Grob JJ, Beylot-Barry M, Saiag P, Fléchon A, You B, Maubec E, Jouary T, Toulemonde E, Jamme P, Gambotti L, Lamrani-Ghaouti A, Dupuy A, Lebbe C, Seguin NB, Houede N, Leccia MT, Le Du F, de Pontville M, Gaudy-Marquestre C, Guillot B, Simon C, Marabelle A, Mortier L
Eur J Cancer 2022 Dec;177:103-111. Epub 2022 Oct 11 doi: 10.1016/j.ejca.2022.09.013. PMID: 36335780
Sekulic A, Yoo S, Kudchadkar R, Guillen J, Rogers G, Chang ALS, Guenthner S, Raskin B, Dawson K, Mun Y, Chu L, McKenna E, Lacouture M
PLoS One 2022;17(1):e0262151. Epub 2022 Jan 14 doi: 10.1371/journal.pone.0262151. PMID: 35030185Free PMC Article
Marescassier H, Dousset L, Beylot-Barry M, Célérier P, Vaillant L, Bedane C, Leclère F, Wierzbicka-Hainaut E, Masson Regnault M
Dermatology 2021;237(6):1023-1028. Epub 2021 Jan 20 doi: 10.1159/000512889. PMID: 33472195
Curragh DS, Huilgol SC, Selva D
Eye (Lond) 2021 Oct;35(10):2740-2745. Epub 2020 Nov 24 doi: 10.1038/s41433-020-01291-2. PMID: 33235336Free PMC Article
Brown L, David J, Skopit S
J Drugs Dermatol 2018 Mar 1;17(3):358-362. PMID: 29537455

Clinical prediction guides

Herms F, Baroudjian B, Delyon J, Laly P, Tetu P, Lebbe C, Basset-Seguin N
Acta Derm Venereol 2022 May 23;102:adv00740. doi: 10.2340/actadv.v102.1995. PMID: 35604234Free PMC Article
Damsin T, Lebas E, Marchal N, Rorive A, Nikkels AF
Expert Rev Anticancer Ther 2022 Mar;22(3):243-248. Epub 2022 Feb 22 doi: 10.1080/14737140.2022.2043748. PMID: 35175882
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Curragh DS, Huilgol SC, Selva D
Eye (Lond) 2021 Oct;35(10):2740-2745. Epub 2020 Nov 24 doi: 10.1038/s41433-020-01291-2. PMID: 33235336Free PMC Article
Khoo AB, Ali FR, Lear JT
Curr Opin Oncol 2016 Mar;28(2):180-4. doi: 10.1097/CCO.0000000000000259. PMID: 26780190

Recent systematic reviews

Patel A, Kim JS, Liss J, Howard L, Jung SH, Kheterpal M
Dermatol Ther 2021 Nov;34(6):e15172. Epub 2021 Oct 28 doi: 10.1111/dth.15172. PMID: 34676633
Jacobsen AA, Aldahan AS, Hughes OB, Shah VV, Strasswimmer J
JAMA Dermatol 2016 Jul 1;152(7):816-24. doi: 10.1001/jamadermatol.2016.0780. PMID: 27096888

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