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Locally Advanced Breast Carcinoma

MedGen UID:
1703295
•Concept ID:
C5205659
•
Neoplastic Process

Definition

A breast carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Surgical management of locally advanced breast cancer: Recommendations of the Brazilian Society of Surgical Oncology.
da Costa Vieira RA, Andrade WP, Vieira SC, Romano M, Iglesias G, Oliveira AF
J Surg Oncol 2022 Jul;126(1):57-67. doi: 10.1002/jso.26890. PMID: 35689588
Treatment failure following sequential thermoradiotherapy of locally advanced breast carcinoma occurs primarily in poorly vascularized tumors.
Lyng H, Rofstad EK
Oncology 1995 Nov-Dec;52(6):443-7. doi: 10.1159/000227508. PMID: 7478428
Multimodality treatment of locally advanced breast carcinoma.
Hobar PC, Jones RC, Schouten J, Leitch AM, Hendler F
Arch Surg 1988 Aug;123(8):951-5. doi: 10.1001/archsurg.1988.01400320037006. PMID: 3395238

Recent clinical studies

Therapy

Clinical Internal Dosimetry and Biodistribution of 177 Lu-DOTA-Trastuzumab in HER2-Positive Metastatic and Locally Advanced Breast Carcinoma.
Narwadkar YS, Parghane RV, Sahu S, Lad S, Deep K, Wanage G, Suralkar T, Banerjee S, Gupta S, Basu S, Badwe RA
Clin Nucl Med 2024 Apr 1;49(4):e149-e155. Epub 2024 Feb 1 doi: 10.1097/RLU.0000000000005067. PMID: 38350067
Label-free multiphoton imaging to assess neoadjuvant therapy responses in breast carcinoma.
Li L, Han Z, Qiu L, Kang D, Zhan Z, Tu H, Chen J
Int J Biol Sci 2020;16(8):1376-1387. Epub 2020 Feb 21 doi: 10.7150/ijbs.41579. PMID: 32210726Free PMC Article
Axillary reverse mapping: Is it feasible in locally advanced breast cancer patients?
Khandelwal R, Poovamma CU, Shilpy C, Prema M, Anthony P
Breast Dis 2014 Jan 1;34(4):151-5. doi: 10.3233/BD-140371. PMID: 24934169
Locally advanced breast carcinoma: evaluation of mammography in the prediction of residual disease after induction chemotherapy.
Huber S, Wagner M, Zuna I, Medl M, Czembirek H, Delorme S
Anticancer Res 2000 Jan-Feb;20(1B):553-8. PMID: 10769724
Multimodal therapy in locally advanced breast carcinoma.
Lopez MJ, Andriole DP, Kraybill WG, Khojasteh A
Am J Surg 1990 Dec;160(6):669-74; discussion 674-5. doi: 10.1016/s0002-9610(05)80772-x. PMID: 2252134

Prognosis

Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy.
Yuan L, Li JJ, Li CQ, Yan CG, Cheng ZL, Wu YK, Hao P, Lin BQ, Xu YK
Cancer Imaging 2018 Oct 29;18(1):38. doi: 10.1186/s40644-018-0173-5. PMID: 30373679Free PMC Article
Association between mammographic features and response to neoadjuvant chemotherapy in locally advanced breast carcinoma.
Castaneda CA, Flores R, Rojas K, Flores C, Castillo M, Milla E
Hematol Oncol Stem Cell Ther 2014 Dec;7(4):149-56. Epub 2014 Oct 6 doi: 10.1016/j.hemonc.2014.09.001. PMID: 25300565
Inflammatory breast carcinoma and noninflammatory locally advanced breast carcinoma: distinct clinicopathologic entities?
Anderson WF, Chu KC, Chang S
J Clin Oncol 2003 Jun 15;21(12):2254-9. doi: 10.1200/JCO.2003.07.082. PMID: 12805323
Multimodal therapy in locally advanced breast carcinoma.
Lopez MJ, Andriole DP, Kraybill WG, Khojasteh A
Am J Surg 1990 Dec;160(6):669-74; discussion 674-5. doi: 10.1016/s0002-9610(05)80772-x. PMID: 2252134
Locally advanced breast carcinoma: results with combined regional therapy.
Toonkel LM, Fix I, Jacobson LH, Bamberg N, Wallach CB
Int J Radiat Oncol Biol Phys 1986 Sep;12(9):1583-7. doi: 10.1016/0360-3016(86)90281-6. PMID: 3759583

Clinical prediction guides

Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy.
Yuan L, Li JJ, Li CQ, Yan CG, Cheng ZL, Wu YK, Hao P, Lin BQ, Xu YK
Cancer Imaging 2018 Oct 29;18(1):38. doi: 10.1186/s40644-018-0173-5. PMID: 30373679Free PMC Article
Association between mammographic features and response to neoadjuvant chemotherapy in locally advanced breast carcinoma.
Castaneda CA, Flores R, Rojas K, Flores C, Castillo M, Milla E
Hematol Oncol Stem Cell Ther 2014 Dec;7(4):149-56. Epub 2014 Oct 6 doi: 10.1016/j.hemonc.2014.09.001. PMID: 25300565
Axillary reverse mapping: Is it feasible in locally advanced breast cancer patients?
Khandelwal R, Poovamma CU, Shilpy C, Prema M, Anthony P
Breast Dis 2014 Jan 1;34(4):151-5. doi: 10.3233/BD-140371. PMID: 24934169
Clinical and radiological predictors of nipple-areola complex involvement in breast cancer patients.
D'Alonzo M, Martincich L, Biglia N, Pisacane A, Maggiorotto F, Rosa GD, Montemurro F, Kubatzki F, Sismondi P, Ponzone R
Eur J Cancer 2012 Oct;48(15):2311-8. Epub 2012 May 28 doi: 10.1016/j.ejca.2012.04.017. PMID: 22647686
Inflammatory breast carcinoma and noninflammatory locally advanced breast carcinoma: distinct clinicopathologic entities?
Anderson WF, Chu KC, Chang S
J Clin Oncol 2003 Jun 15;21(12):2254-9. doi: 10.1200/JCO.2003.07.082. PMID: 12805323

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