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Unresectable Bile Duct Carcinoma

MedGen UID:
1771049
Concept ID:
C5419081
Neoplastic Process

Definition

Bile duct carcinoma that is not amenable to surgical resection. [from NCI]

Professional guidelines

PubMed

Tamada K, Sugano K
J Gastroenterol 2000;35(5):319-25. doi: 10.1007/s005350050355. PMID: 10832665

Recent clinical studies

Etiology

Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł, Scripcariu V, Grazi GL, Landa-Magdalena A, Ijzermans JN, Evert K, Erdmann JI, López-López F, Saborowski A, Scheiter A, Santos-Laso A, Carpino G, Andersen JB, Marin JJ, Alvaro D, Bujanda L, Forner A, Valle JW, Koerkamp BG, Banales JM
J Hepatol 2022 May;76(5):1109-1121. Epub 2022 Feb 12 doi: 10.1016/j.jhep.2021.12.010. PMID: 35167909
Mazzaferro V, Gorgen A, Roayaie S, Droz Dit Busset M, Sapisochin G
J Hepatol 2020 Feb;72(2):364-377. doi: 10.1016/j.jhep.2019.11.020. PMID: 31954498
El-Diwany R, Pawlik TM, Ejaz A
Surg Oncol Clin N Am 2019 Oct;28(4):587-599. doi: 10.1016/j.soc.2019.06.002. PMID: 31472907
Zhang H, Yang T, Wu M, Shen F
Cancer Lett 2016 Sep 1;379(2):198-205. Epub 2015 Sep 25 doi: 10.1016/j.canlet.2015.09.008. PMID: 26409434

Diagnosis

Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł, Scripcariu V, Grazi GL, Landa-Magdalena A, Ijzermans JN, Evert K, Erdmann JI, López-López F, Saborowski A, Scheiter A, Santos-Laso A, Carpino G, Andersen JB, Marin JJ, Alvaro D, Bujanda L, Forner A, Valle JW, Koerkamp BG, Banales JM
J Hepatol 2022 May;76(5):1109-1121. Epub 2022 Feb 12 doi: 10.1016/j.jhep.2021.12.010. PMID: 35167909
Dondossola D, Ghidini M, Grossi F, Rossi G, Foschi D
World J Gastroenterol 2020 Jul 7;26(25):3542-3561. doi: 10.3748/wjg.v26.i25.3542. PMID: 32742125Free PMC Article
Mazzaferro V, Gorgen A, Roayaie S, Droz Dit Busset M, Sapisochin G
J Hepatol 2020 Feb;72(2):364-377. doi: 10.1016/j.jhep.2019.11.020. PMID: 31954498
Zhang H, Yang T, Wu M, Shen F
Cancer Lett 2016 Sep 1;379(2):198-205. Epub 2015 Sep 25 doi: 10.1016/j.canlet.2015.09.008. PMID: 26409434

Therapy

Goyal L, Meric-Bernstam F, Hollebecque A, Valle JW, Morizane C, Karasic TB, Abrams TA, Furuse J, Kelley RK, Cassier PA, Klümpen HJ, Chang HM, Chen LT, Tabernero J, Oh DY, Mahipal A, Moehler M, Mitchell EP, Komatsu Y, Masuda K, Ahn D, Epstein RS, Halim AB, Fu Y, Salimi T, Wacheck V, He Y, Liu M, Benhadji KA, Bridgewater JA; FOENIX-CCA2 Study Investigators
N Engl J Med 2023 Jan 19;388(3):228-239. doi: 10.1056/NEJMoa2206834. PMID: 36652354
Moris D, Palta M, Kim C, Allen PJ, Morse MA, Lidsky ME
CA Cancer J Clin 2023 Mar;73(2):198-222. Epub 2022 Oct 19 doi: 10.3322/caac.21759. PMID: 36260350
Weaver A, Bossaer JB
J Oncol Pharm Pract 2021 Apr;27(3):702-710. Epub 2020 Dec 29 doi: 10.1177/1078155220983425. PMID: 33375902
Dondossola D, Ghidini M, Grossi F, Rossi G, Foschi D
World J Gastroenterol 2020 Jul 7;26(25):3542-3561. doi: 10.3748/wjg.v26.i25.3542. PMID: 32742125Free PMC Article
Mazzaferro V, Gorgen A, Roayaie S, Droz Dit Busset M, Sapisochin G
J Hepatol 2020 Feb;72(2):364-377. doi: 10.1016/j.jhep.2019.11.020. PMID: 31954498

Prognosis

Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł, Scripcariu V, Grazi GL, Landa-Magdalena A, Ijzermans JN, Evert K, Erdmann JI, López-López F, Saborowski A, Scheiter A, Santos-Laso A, Carpino G, Andersen JB, Marin JJ, Alvaro D, Bujanda L, Forner A, Valle JW, Koerkamp BG, Banales JM
J Hepatol 2022 May;76(5):1109-1121. Epub 2022 Feb 12 doi: 10.1016/j.jhep.2021.12.010. PMID: 35167909
Mazzaferro V, Gorgen A, Roayaie S, Droz Dit Busset M, Sapisochin G
J Hepatol 2020 Feb;72(2):364-377. doi: 10.1016/j.jhep.2019.11.020. PMID: 31954498
El-Diwany R, Pawlik TM, Ejaz A
Surg Oncol Clin N Am 2019 Oct;28(4):587-599. doi: 10.1016/j.soc.2019.06.002. PMID: 31472907
Zhang H, Yang T, Wu M, Shen F
Cancer Lett 2016 Sep 1;379(2):198-205. Epub 2015 Sep 25 doi: 10.1016/j.canlet.2015.09.008. PMID: 26409434

Clinical prediction guides

Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł, Scripcariu V, Grazi GL, Landa-Magdalena A, Ijzermans JN, Evert K, Erdmann JI, López-López F, Saborowski A, Scheiter A, Santos-Laso A, Carpino G, Andersen JB, Marin JJ, Alvaro D, Bujanda L, Forner A, Valle JW, Koerkamp BG, Banales JM
J Hepatol 2022 May;76(5):1109-1121. Epub 2022 Feb 12 doi: 10.1016/j.jhep.2021.12.010. PMID: 35167909
El-Diwany R, Pawlik TM, Ejaz A
Surg Oncol Clin N Am 2019 Oct;28(4):587-599. doi: 10.1016/j.soc.2019.06.002. PMID: 31472907
Hong TS, Wo JY, Yeap BY, Ben-Josef E, McDonnell EI, Blaszkowsky LS, Kwak EL, Allen JN, Clark JW, Goyal L, Murphy JE, Javle MM, Wolfgang JA, Drapek LC, Arellano RS, Mamon HJ, Mullen JT, Yoon SS, Tanabe KK, Ferrone CR, Ryan DP, DeLaney TF, Crane CH, Zhu AX
J Clin Oncol 2016 Feb 10;34(5):460-8. Epub 2015 Dec 14 doi: 10.1200/JCO.2015.64.2710. PMID: 26668346Free PMC Article
Zhang H, Yang T, Wu M, Shen F
Cancer Lett 2016 Sep 1;379(2):198-205. Epub 2015 Sep 25 doi: 10.1016/j.canlet.2015.09.008. PMID: 26409434
Padia SA
Tech Vasc Interv Radiol 2015 Dec;18(4):227-35. Epub 2015 Jul 15 doi: 10.1053/j.tvir.2015.07.006. PMID: 26615163

Recent systematic reviews

Holster JJ, El Hassnaoui M, Franssen S, IJzermans JNM, de Jonge J, Mostert B, Polak WG, de Wilde RF, Homs MYV, Groot Koerkamp B
Ann Surg Oncol 2022 Sep;29(9):5528-5538. Epub 2022 Mar 16 doi: 10.1245/s10434-022-11439-x. PMID: 35294656Free PMC Article
Schartz DA, Porter M, Schartz E, Kallas J, Gupta A, Butani D, Cantos A
J Vasc Interv Radiol 2022 Jun;33(6):679-686. Epub 2022 Feb 25 doi: 10.1016/j.jvir.2022.02.016. PMID: 35219834
Mosconi C, Solaini L, Vara G, Brandi N, Cappelli A, Modestino F, Cucchetti A, Golfieri R
Cardiovasc Intervent Radiol 2021 May;44(5):728-738. Epub 2021 Mar 11 doi: 10.1007/s00270-021-02800-w. PMID: 33709272
Ku D, Tang R, Pang T, Pleass H, Richardson A, Yuen L, Lam V
ANZ J Surg 2020 Sep;90(9):1604-1614. Epub 2019 Dec 15 doi: 10.1111/ans.15531. PMID: 31840387
Mattiucci GC, Autorino R, D'Agostino GR, Deodato F, Macchia G, Perri V, Tringali A, Morganti AG, Mutignani M, Valentini V
Crit Rev Oncol Hematol 2014 Apr;90(1):58-67. Epub 2013 Nov 2 doi: 10.1016/j.critrevonc.2013.10.007. PMID: 24289902

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