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Rectal Conventional Adenoma

MedGen UID:
1773894
•Concept ID:
C5419785
•
Neoplastic Process

Definition

A benign, premalignant rectal neoplasm composed of dysplastic epithelium. The descriptor ""conventional"" distinguishes this from lesions in the serrated pathway. (WHO 2019) [from NCI]

Professional guidelines

PubMed

ACR Appropriateness Criteria pretreatment staging of colorectal cancer.
Dewhurst C, Rosen MP, Blake MA, Baker ME, Cash BD, Fidler JL, Greene FL, Hindman NM, Jones B, Katz DS, Lalani T, Miller FH, Small WC, Sudakoff GS, Tulchinsky M, Yaghmai V, Yee J
J Am Coll Radiol 2012 Nov;9(11):775-81. doi: 10.1016/j.jacr.2012.07.025. PMID: 23122343
Minimal invasive surgery in the local treatment of rectal cancer.
Said S, Stippel D, Zieren J
Ann Chir Gynaecol 1994;83(2):167-73. PMID: 7944219
Villous adenomas of the rectum. Results of endoscopic treatment with argon and Nd:YAG lasers.
Brunetaud JM, Mosquet L, Houcke M, Scopelliti JA, Rance FA, Cortot A, Paris JC
Gastroenterology 1985 Oct;89(4):832-7. PMID: 4029563

Recent clinical studies

Etiology

Robotic transanal minimally invasive surgery: a case series.
Lo KW, Blitzer DN, Shoucair S, Lisle DM
Surg Endosc 2022 Jan;36(1):793-799. Epub 2021 Jan 8 doi: 10.1007/s00464-020-08257-1. PMID: 33416992
Simple Sugar and Sugar-Sweetened Beverage Intake During Adolescence and Risk of Colorectal Cancer Precursors.
Joh HK, Lee DH, Hur J, Nimptsch K, Chang Y, Joung H, Zhang X, Rezende LFM, Lee JE, Ng K, Yuan C, Tabung FK, Meyerhardt JA, Chan AT, Pischon T, Song M, Fuchs CS, Willett WC, Cao Y, Ogino S, Giovannucci E, Wu K
Gastroenterology 2021 Jul;161(1):128-142.e20. Epub 2021 Mar 19 doi: 10.1053/j.gastro.2021.03.028. PMID: 33753105Free PMC Article
Impact of medical therapies on inflammatory bowel disease complication rate.
Reenaers C, Belaiche J, Louis E
World J Gastroenterol 2012 Aug 7;18(29):3823-7. doi: 10.3748/wjg.v18.i29.3823. PMID: 22876033Free PMC Article
Narrow band imaging versus conventional white light colonoscopy for the detection of colorectal polyps.
Nagorni A, Bjelakovic G, Petrovic B
Cochrane Database Syst Rev 2012 Jan 18;1:CD008361. doi: 10.1002/14651858.CD008361.pub2. PMID: 22258983
Laparoscopic colonic resection.
Lezoche E, Feliciotti F, Paganini AM, Guerrieri M, De Sanctis A, Campagnacci R
J Laparoendosc Adv Surg Tech A 2001 Dec;11(6):401-8. doi: 10.1089/10926420152761932. PMID: 11814132

Diagnosis

Simple Sugar and Sugar-Sweetened Beverage Intake During Adolescence and Risk of Colorectal Cancer Precursors.
Joh HK, Lee DH, Hur J, Nimptsch K, Chang Y, Joung H, Zhang X, Rezende LFM, Lee JE, Ng K, Yuan C, Tabung FK, Meyerhardt JA, Chan AT, Pischon T, Song M, Fuchs CS, Willett WC, Cao Y, Ogino S, Giovannucci E, Wu K
Gastroenterology 2021 Jul;161(1):128-142.e20. Epub 2021 Mar 19 doi: 10.1053/j.gastro.2021.03.028. PMID: 33753105Free PMC Article
Antibiotic Use Associated With Risk of Colorectal Polyps in a Nationwide Study.
Song M, Nguyen LH, Emilsson L, Chan AT, Ludvigsson JF
Clin Gastroenterol Hepatol 2021 Jul;19(7):1426-1435.e6. Epub 2020 May 23 doi: 10.1016/j.cgh.2020.05.036. PMID: 32454258Free PMC Article
The third pathway of colorectal carcinogenesis.
Rubio CA, Puppa G, de Petris G, Kis L, Schmidt PT
J Clin Pathol 2018 Jan;71(1):7-11. Epub 2017 Jul 27 doi: 10.1136/jclinpath-2017-204660. PMID: 28751521
Narrow band imaging versus conventional white light colonoscopy for the detection of colorectal polyps.
Nagorni A, Bjelakovic G, Petrovic B
Cochrane Database Syst Rev 2012 Jan 18;1:CD008361. doi: 10.1002/14651858.CD008361.pub2. PMID: 22258983
Radioimmunodetection of colorectal cancer.
Kim EE, Deland FH, Casper S, Corgan RL, Primus FJ, Goldenberg DM
Cancer 1980 Mar 15;45(5 Suppl):1243-7. doi: 10.1002/1097-0142(19800315)45:5+<1243::aid-cncr2820451334>3.0.co;2-1. PMID: 7357516

Therapy

Endoscopic resection of residual rectal neoplasia after definitive chemoradiotherapy for rectal cancer.
Klimkowski R, Krzyzkowiak J, Pilonis ND, Bujko K, Kaminski MF
Best Pract Res Clin Gastroenterol 2024 Feb;68:101896. Epub 2024 Feb 28 doi: 10.1016/j.bpg.2024.101896. PMID: 38522889
Simple Sugar and Sugar-Sweetened Beverage Intake During Adolescence and Risk of Colorectal Cancer Precursors.
Joh HK, Lee DH, Hur J, Nimptsch K, Chang Y, Joung H, Zhang X, Rezende LFM, Lee JE, Ng K, Yuan C, Tabung FK, Meyerhardt JA, Chan AT, Pischon T, Song M, Fuchs CS, Willett WC, Cao Y, Ogino S, Giovannucci E, Wu K
Gastroenterology 2021 Jul;161(1):128-142.e20. Epub 2021 Mar 19 doi: 10.1053/j.gastro.2021.03.028. PMID: 33753105Free PMC Article
Impact of medical therapies on inflammatory bowel disease complication rate.
Reenaers C, Belaiche J, Louis E
World J Gastroenterol 2012 Aug 7;18(29):3823-7. doi: 10.3748/wjg.v18.i29.3823. PMID: 22876033Free PMC Article
Narrow band imaging versus conventional white light colonoscopy for the detection of colorectal polyps.
Nagorni A, Bjelakovic G, Petrovic B
Cochrane Database Syst Rev 2012 Jan 18;1:CD008361. doi: 10.1002/14651858.CD008361.pub2. PMID: 22258983
Laparoscopic colonic resection.
Lezoche E, Feliciotti F, Paganini AM, Guerrieri M, De Sanctis A, Campagnacci R
J Laparoendosc Adv Surg Tech A 2001 Dec;11(6):401-8. doi: 10.1089/10926420152761932. PMID: 11814132

Prognosis

A novel tool for case selection in endoscopic mucosal resection training.
O'Sullivan T, Sidhu M, Gupta S, Byth K, Elhindi J, Tate D, Cronin O, Whitfield A, Wang H, Lee E, Williams S, Burgess NG, Bourke MJ
Endoscopy 2023 Dec;55(12):1095-1102. Epub 2023 Jun 30 doi: 10.1055/a-2121-1148. PMID: 37391184
Cost effectiveness of using Faecal Immunochemical Testing (FIT) as an initial diagnostic investigation for patients with lower gastrointestinal symptoms suggestive of malignancy.
Kearsey CC, Graham C, Lobb HS, Chacko J, Weatherburn R, Rooney PS
BMC Fam Pract 2021 May 12;22(1):90. doi: 10.1186/s12875-021-01435-7. PMID: 33980161Free PMC Article
Recurrence rates after EMR of large sessile serrated polyps.
Rex KD, Vemulapalli KC, Rex DK
Gastrointest Endosc 2015 Sep;82(3):538-41. Epub 2015 Apr 4 doi: 10.1016/j.gie.2015.01.025. PMID: 25851161
Impact of medical therapies on inflammatory bowel disease complication rate.
Reenaers C, Belaiche J, Louis E
World J Gastroenterol 2012 Aug 7;18(29):3823-7. doi: 10.3748/wjg.v18.i29.3823. PMID: 22876033Free PMC Article
Review: transanal endoscopic microsurgery (TEM).
Buess G
J R Coll Surg Edinb 1993 Aug;38(4):239-45. PMID: 7693935

Clinical prediction guides

A novel tool for case selection in endoscopic mucosal resection training.
O'Sullivan T, Sidhu M, Gupta S, Byth K, Elhindi J, Tate D, Cronin O, Whitfield A, Wang H, Lee E, Williams S, Burgess NG, Bourke MJ
Endoscopy 2023 Dec;55(12):1095-1102. Epub 2023 Jun 30 doi: 10.1055/a-2121-1148. PMID: 37391184
Cost effectiveness of using Faecal Immunochemical Testing (FIT) as an initial diagnostic investigation for patients with lower gastrointestinal symptoms suggestive of malignancy.
Kearsey CC, Graham C, Lobb HS, Chacko J, Weatherburn R, Rooney PS
BMC Fam Pract 2021 May 12;22(1):90. doi: 10.1186/s12875-021-01435-7. PMID: 33980161Free PMC Article
Antibiotic Use Associated With Risk of Colorectal Polyps in a Nationwide Study.
Song M, Nguyen LH, Emilsson L, Chan AT, Ludvigsson JF
Clin Gastroenterol Hepatol 2021 Jul;19(7):1426-1435.e6. Epub 2020 May 23 doi: 10.1016/j.cgh.2020.05.036. PMID: 32454258Free PMC Article
Candida albicans culture from a rectal swab can be associated with newly diagnosed colorectal cancer.
Starý L, Mezerová K, Vysloužil K, Zbořil P, Skalický P, Stašek M, Raclavský V
Folia Microbiol (Praha) 2020 Dec;65(6):989-994. Epub 2020 Jun 29 doi: 10.1007/s12223-020-00807-3. PMID: 32602070
Laparoscopic colonic resection.
Lezoche E, Feliciotti F, Paganini AM, Guerrieri M, De Sanctis A, Campagnacci R
J Laparoendosc Adv Surg Tech A 2001 Dec;11(6):401-8. doi: 10.1089/10926420152761932. PMID: 11814132

Recent systematic reviews

Non-conventional applications for transanal endoscopic microsurgery. A single center experience and a systematic review of literature.
DE Vincenti R, Cianchi F, Coratti F
Minerva Surg 2022 Apr;77(2):147-156. Epub 2021 May 28 doi: 10.23736/S2724-5691.21.08774-8. PMID: 34047531
Narrow band imaging versus conventional white light colonoscopy for the detection of colorectal polyps.
Nagorni A, Bjelakovic G, Petrovic B
Cochrane Database Syst Rev 2012 Jan 18;1:CD008361. doi: 10.1002/14651858.CD008361.pub2. PMID: 22258983

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