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Rectal Conventional Adenoma

MedGen UID:
1773894
Concept ID:
C5419785
Neoplastic Process

Definition

A benign, premalignant rectal neoplasm composed of dysplastic epithelium. The descriptor ""conventional"" distinguishes this from lesions in the serrated pathway. (WHO 2019) [from NCI]

Professional guidelines

PubMed

Dewhurst C, Rosen MP, Blake MA, Baker ME, Cash BD, Fidler JL, Greene FL, Hindman NM, Jones B, Katz DS, Lalani T, Miller FH, Small WC, Sudakoff GS, Tulchinsky M, Yaghmai V, Yee J
J Am Coll Radiol 2012 Nov;9(11):775-81. doi: 10.1016/j.jacr.2012.07.025. PMID: 23122343
Said S, Stippel D, Zieren J
Ann Chir Gynaecol 1994;83(2):167-73. PMID: 7944219
Brunetaud JM, Mosquet L, Houcke M, Scopelliti JA, Rance FA, Cortot A, Paris JC
Gastroenterology 1985 Oct;89(4):832-7. PMID: 4029563

Recent clinical studies

Etiology

Lo KW, Blitzer DN, Shoucair S, Lisle DM
Surg Endosc 2022 Jan;36(1):793-799. Epub 2021 Jan 8 doi: 10.1007/s00464-020-08257-1. PMID: 33416992
Joh HK, Lee DH, Hur J, Nimptsch K, Chang Y, Joung H, Zhang X, Rezende LFM, Lee JE, Ng K, Yuan C, Tabung FK, Meyerhardt JA, Chan AT, Pischon T, Song M, Fuchs CS, Willett WC, Cao Y, Ogino S, Giovannucci E, Wu K
Gastroenterology 2021 Jul;161(1):128-142.e20. Epub 2021 Mar 19 doi: 10.1053/j.gastro.2021.03.028. PMID: 33753105Free PMC Article
Reenaers C, Belaiche J, Louis E
World J Gastroenterol 2012 Aug 7;18(29):3823-7. doi: 10.3748/wjg.v18.i29.3823. PMID: 22876033Free PMC Article
Nagorni A, Bjelakovic G, Petrovic B
Cochrane Database Syst Rev 2012 Jan 18;1:CD008361. doi: 10.1002/14651858.CD008361.pub2. PMID: 22258983
Burghardt J, Buess G
Surg Technol Int 2005;14:131-7. PMID: 16525965

Diagnosis

Joh HK, Lee DH, Hur J, Nimptsch K, Chang Y, Joung H, Zhang X, Rezende LFM, Lee JE, Ng K, Yuan C, Tabung FK, Meyerhardt JA, Chan AT, Pischon T, Song M, Fuchs CS, Willett WC, Cao Y, Ogino S, Giovannucci E, Wu K
Gastroenterology 2021 Jul;161(1):128-142.e20. Epub 2021 Mar 19 doi: 10.1053/j.gastro.2021.03.028. PMID: 33753105Free PMC Article
Song M, Nguyen LH, Emilsson L, Chan AT, Ludvigsson JF
Clin Gastroenterol Hepatol 2021 Jul;19(7):1426-1435.e6. Epub 2020 May 23 doi: 10.1016/j.cgh.2020.05.036. PMID: 32454258Free PMC Article
Rubio CA, Puppa G, de Petris G, Kis L, Schmidt PT
J Clin Pathol 2018 Jan;71(1):7-11. Epub 2017 Jul 27 doi: 10.1136/jclinpath-2017-204660. PMID: 28751521
Nagorni A, Bjelakovic G, Petrovic B
Cochrane Database Syst Rev 2012 Jan 18;1:CD008361. doi: 10.1002/14651858.CD008361.pub2. PMID: 22258983
Burghardt J, Buess G
Surg Technol Int 2005;14:131-7. PMID: 16525965

Therapy

Joh HK, Lee DH, Hur J, Nimptsch K, Chang Y, Joung H, Zhang X, Rezende LFM, Lee JE, Ng K, Yuan C, Tabung FK, Meyerhardt JA, Chan AT, Pischon T, Song M, Fuchs CS, Willett WC, Cao Y, Ogino S, Giovannucci E, Wu K
Gastroenterology 2021 Jul;161(1):128-142.e20. Epub 2021 Mar 19 doi: 10.1053/j.gastro.2021.03.028. PMID: 33753105Free PMC Article
Song M, Nguyen LH, Emilsson L, Chan AT, Ludvigsson JF
Clin Gastroenterol Hepatol 2021 Jul;19(7):1426-1435.e6. Epub 2020 May 23 doi: 10.1016/j.cgh.2020.05.036. PMID: 32454258Free PMC Article
Wanebo HJ, LeGolvan M, Paty PB, Saha S, Zuber M, D'Angelica MI, Kemeny NE
Clin Exp Metastasis 2012 Oct;29(7):821-39. Epub 2012 Oct 10 doi: 10.1007/s10585-012-9517-x. PMID: 23053740
Reenaers C, Belaiche J, Louis E
World J Gastroenterol 2012 Aug 7;18(29):3823-7. doi: 10.3748/wjg.v18.i29.3823. PMID: 22876033Free PMC Article
Nagorni A, Bjelakovic G, Petrovic B
Cochrane Database Syst Rev 2012 Jan 18;1:CD008361. doi: 10.1002/14651858.CD008361.pub2. PMID: 22258983

Prognosis

Rex DK, Adler SN, Aisenberg J, Burch WC Jr, Carretero C, Chowers Y, Fein SA, Fern SE, Fernandez-Urien Sainz I, Fich A, Gal E, Horlander JC Sr, Isaacs KL, Kariv R, Lahat A, Leung WK, Malik PR, Morgan D, Papageorgiou N, Romeo DP, Shah SS, Waterman M
Gastroenterology 2015 May;148(5):948-957.e2. Epub 2015 Jan 22 doi: 10.1053/j.gastro.2015.01.025. PMID: 25620668
Guerrieri M, Baldarelli M, Rimini M, Gesuita R, Lezoche G, Romiti C, Lezoche E
Minerva Chir 2013 Jun;68(3):289-98. PMID: 23774094
Wanebo HJ, LeGolvan M, Paty PB, Saha S, Zuber M, D'Angelica MI, Kemeny NE
Clin Exp Metastasis 2012 Oct;29(7):821-39. Epub 2012 Oct 10 doi: 10.1007/s10585-012-9517-x. PMID: 23053740
Reenaers C, Belaiche J, Louis E
World J Gastroenterol 2012 Aug 7;18(29):3823-7. doi: 10.3748/wjg.v18.i29.3823. PMID: 22876033Free PMC Article
Stipa S, Chiavellati L, Nicolanti V, Stipa F
Dis Colon Rectum 1994 Feb;37(2 Suppl):S81-5. doi: 10.1007/BF02048437. PMID: 8313799

Clinical prediction guides

Song M, Nguyen LH, Emilsson L, Chan AT, Ludvigsson JF
Clin Gastroenterol Hepatol 2021 Jul;19(7):1426-1435.e6. Epub 2020 May 23 doi: 10.1016/j.cgh.2020.05.036. PMID: 32454258Free PMC Article
Starý L, Mezerová K, Vysloužil K, Zbořil P, Skalický P, Stašek M, Raclavský V
Folia Microbiol (Praha) 2020 Dec;65(6):989-994. Epub 2020 Jun 29 doi: 10.1007/s12223-020-00807-3. PMID: 32602070
Guerrieri M, Baldarelli M, Rimini M, Gesuita R, Lezoche G, Romiti C, Lezoche E
Minerva Chir 2013 Jun;68(3):289-98. PMID: 23774094
Lezoche E, Feliciotti F, Paganini AM, Guerrieri M, De Sanctis A, Campagnacci R
J Laparoendosc Adv Surg Tech A 2001 Dec;11(6):401-8. doi: 10.1089/10926420152761932. PMID: 11814132
Stipa S, Chiavellati L, Nicolanti V, Stipa F
Dis Colon Rectum 1994 Feb;37(2 Suppl):S81-5. doi: 10.1007/BF02048437. PMID: 8313799

Recent systematic reviews

DE Vincenti R, Cianchi F, Coratti F
Minerva Surg 2022 Apr;77(2):147-156. Epub 2021 May 28 doi: 10.23736/S2724-5691.21.08774-8. PMID: 34047531
Nagorni A, Bjelakovic G, Petrovic B
Cochrane Database Syst Rev 2012 Jan 18;1:CD008361. doi: 10.1002/14651858.CD008361.pub2. PMID: 22258983

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